Under Development

Information

 

ü Professors and key members

ü Strategic Plan

 

Perspective

Our ultimate goal is to be recognized as a national academic and research hub in pharmaceutical sciences through executing various basic and practical researches in the field of pharmaceutical sciences.

 

Mission

  1. Basic researches in the field of pharmaceutical sciences in order to promote and develop science
  2. Practical researches relative to pharmaceutical sciences in the fields of industry, health, and treatment.
  3. Providing an appropriate environment with necessary equipment and laboratory facilities and inspired and motivated researches in order to perform different researches.
  4. Strong communication with other science centers and attraction of credits from outside the organization.

 

Overall goals

G1. Development and promotion of science through increasing the number of authentic national and international articles.

G2. Performing different practical researches deemed necessary by the society in the fields of treatment, health, and related industries.

G3. Promoting the centers ranking amongst other national science centers.

 

 

ü  Equipment and Facilities

 

Department of Nanomedicine

Supervisor: Dr. Mohammadreza Ramazani (Professor of Medicinal Biotechnology)

Equipment include: MPLC, refrigerated centrifuge, optical microscope, UV cabinet, vacuum centrifuge, ELISA reader, freeze dryer, all equipment required for column chromatography and TLC, sonicator, solvent removal device, and soxhlet device. Four computers with high-speed internet along with scanner and printer.

 

Department of Analysis

Supervisor: Dr. Mohammad Hassanzadeh Khayat (Professor of Medicinal Chemistry)

Equipment include: UV-VIS spectrophotometer, infra-red spectrophotometer, spectrofluorimeter device, high performance liquid chromatography device (HPLC) for analysis of different substances (qualitatively and quantitatively). 2 computers with internet access.

 

Department of Pharmacodynamics

Supervisor: Dr. Hossein Hosseinzadeh (Professor of Pharmacology)

Equipment include: HPLC device, Power Lab device, solvent removal device, hot plate, water maze (MWM), dry heater, oven, microscope with computer connective camera, centrifuge, digital scale, stereotaxy, etc.  Four computers with high-speed internet and one printer.

 

Department of Toxicology and Teratology

Supervisor: Dr. Seyed Adel Moalem (Professor of Toxicology)

Equipment include: tom mice fetus and organ culture device, several stereomicroscopes and digital imaging system for investigating fetal abnormalities, microtome, laminar hood, CO2 incubator and invert microscopes for cell culture, ELISA device, spectrophotometer, PCR gradient device, gel sequencing device, electrophoresis device for studying DNA, RNA, and proteins, and liquid nitrogen tanks for long-term preservation of cells. Two computers with high-speed internet along with two printers.

 

 

 

ü  Research Activities

  • Theses

 

Dr. Imen Shahidi

Effects of Dexrazoxane on aluminum posphide cardiotoxicity in rats

Effects of curcumin on prevention of under chronic cardiovascular damages resulting from Bisphenol A in rats

Protective effects of alcohol extract of lemon verbena leaves and verbascoside effective material on indomethacin-induced peptic ulcer in rat

Protective effect of lemon verbena leaf aqueous extract on indomethacin-induced peptic ulcer in rat

Effects of acute Montmorillonite in acute lithium carbonate–induced toxicity in rat

Dr. Ramazani

DNA aptamer isolation for specific identification of PD-L1(CD274) and performance review

Targeted delivery of irinotecan via Aptamer-PEG-acetylated carboxymethyl cellulose complex to colorectal cancer cells

Electrospun nanofibers containing BMP-2 liposomal peptide to increase mesenchymal stem cell differentiation to bone

PLGA-based nanoparticles loaded with doxorubicin and targeted using PNC-27 peptide as a targeted anti-cancer system

Evaluation of targeted pharmaceuticals to breast cancer cells resistant to MCF/7MX drug using ABCG2 specific aptamer transporter

Effects of crocin and crocetin substances extracted from saffron on mesenchymal cell differentiation in bone cells

Effects of saffron-extracted crocetin and PLGA nanoparticles containing crocetin on incidence of multi-drug resistance phenotype

Procurement of antigen-containing exosomal nanocarriers for tumor treatment

Dr. Abnoos

DNA aptamer isolation for specific identification of PD-L1(CD274) and performance review

Carbon paste electrode-based electrochemical sensors modified using polymer molecule framework nanoparticles for determining Diazinon dosage

Targeted delivery of irinotecan via Aptamer-PEG-acetylated carboxymethyl cellulose complex to colorectal cancer cells

Evaluation of targeted pharmaceuticals to breast cancer cells resistant to MCF/7MX drug using ABCG2 specific aptamer transporter

PLGA-based nanoparticles loaded with doxorubicin and targeted using PNC-27 peptide as a targeted anti-cancer system

Procurement of antigen-containing exosomal nanocarriers for tumor treatment

Dr. Mehri

Effects of tropisetron on oxazaphosphorine-induced hemorrhagic cystic (cyclophosphamide or ifosfamide) in rat

Dr. Hosseinzadeh

Mechanism review of protective effects of crocin on cell toxicity resulting from oxidative stress in isolated hepatocytes in rat

Effects of crocin on human lymphocyte proliferation and Thelper1 and Thelper2 balance

Protective effects of Q10 co-enzyme on acrylamide-induced neurotoxicity in in vivo and in vitro models

Effects of safranal on metabolic disorders resulting from olanzapine consumption in rat

Anti-depressant effects of grape seed extract and resveratrol on postpartum forced swimming and depression model in mice

Effects of crocin on inducing phenotype switching of macrophages to anti-inflammatory M2 state

Effects of thymoquinone on D-galactose induced aging model in rat: memory disorders and its mechanisms

Effects of crocin on nerve damage induced by D-galactose induced aging model in cellular (SH-SS5Y) and animal (rat) environment

Anti-depressant effect of aqueous and ethanol extracts of lemon verbena leaves and its primary substance, verbascoside, on postpartum forced swimming and depression model in mice

Dr. Leila Etemad

Effects of cinnamic aldehyde on methamphetamine-induced nerve damage in PC12 cell

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

in vivo evaluation of aromatase enzyme inhibition using a new composition of 4-(1-imidazole-1-Il)methyl-2-4-methoxy-phenyl benzo quinoline in rat

Anticonvulsant effects of Suvorexant in mice

Effects of acute Montmorillonite on acute lithium carbonate-induced toxicity in rat

Effects of curcumin nanomicelles on phosphine-induced cell damage in HepG2 cell

Effects of pregabalin on nerve evolution using mouse embryonic stem cells

Dr. Seyed Adel Moalem

Effects of cinnamic aldehyde on methamphetamine-induced cell damage in PC12 cell

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

Effects of acute Montmorillonite on acute lithium carbonate-induced toxicity in rat

Effects of pregabalin on nerve evolution using mouse embryonic stem cells

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with potential biomarkers effecting atherosclerosis in patients suffering from chronic cardiac ischemia

Dr. Roohbakhsh

Effects of flavonoid dihydromirestin on expression and acquisition of CPP and symptoms of morphine-induced addiction in mice

Dr. Saeed Islami

 

Anti-depressant effects of saffron stigma in pregnant women suffering from postpartum depression

Anti-depressant effects of saffron stigma tablets on pregnant women suffering from non-major postpartum depression

Study on the relationship between NSAIDS consumption and gastrointestinal bleeding in patients with upper gastrointestinal bleeding referring to Qaem Hospital during 2014

Rational prescription of clozapine and prevalence of agranulocytosis in a sample from Ibn Sina Psychiatry Hospital of Mashhad.

Investigation of doctors prescribing behavior pregnant mothers regarding insurance prescriptions in Razavi Khorasan Province in order to assess inappropriate prescriptions of drugs during pregnancy and establish localized drug prescription instructions for pregnancy consistent with national status.

Relationship between anxiety and educational performance in Mashhad Pharmacy School students

Dr. Mohammad Hasanzadeh Khayat

Carbon paste electrode-based electrochemical sensors modified using polymer molecule framework nanoparticles for determining Diazinon dosage

 

Evaluation of serum concentrations of neopterin as an individual cardiovascular biomarker in patients suffering from coronary artery diseases

Amount of ethanol and methanol in alcohol-free beer brands in Iranian markets

Dr. Afrasiabi

Effects of different types and concentrations of plasticizers on characteristics of microcapsules from three different ethyl cellulose viscosities containing sodium diclophenac procured using emulsion-evaporation of solvent method

Procurement and evaluation of slow-release metoprolol microcapsules using eudragit RS polymers and ethyl cellulose

Performance review of Carr’s Index and Hausner Ratio for determining characteristics of powder flows and evaluating the effects of factors such as powder particle size and type and amount of glidant on these indicators

Comparison of the effects of nerolidol and oleic acid as an enhancer for skin permeability of diclophenac D –ethyl amine in patches provided using R-L eudragit base

Dr. Amir Hooshang Mohamadpoor

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

Evaluation of serum concentrations of neopterin as an individual cardiovascular biomarker in patients suffering from coronary artery diseases

Effects of topical creams containing honey and aloe vera in treatment of radiotherapy-induced dermatitis in breast cancer patients

Dr. Seyed Ahmad Mohajeri

Evaluation of vitamin A suppositories for vaginal use

Protective effects of crocin and corcetin against hyperglycemic damage in retina cells

Procurement of fluorometholone molecular molded hydrogels as ocular drug delivery systems and investigation of binding properties of the drug and its release into the environment

 

 

 

 

  • Articles
    • 2011 publications
  1. Interaction of methylxanthines and gentamicin against Staphylococcus aureus and Pseudomonas aeruginosa: Role of phosphodiesterase inhibition
  2. Euphorbia Microsciadia Percolatio A D Soxhlet Extracts Exhibit A Tiviral Activity
  3. Effects of Aqueous and Ethanolic Leaf Extracts of Mentha Longifolia on Morphine Dependence in Mice
  4. Effects of Crocin on the Acquisition and Reinstatement of Morphine-induced Conditioned Place Preference in Mice
  5. Inhibitory Effect Of Aqueous Extract Of Saffro (Crocus Sativus L.) O Adjuva T-I Duced Arthritis I Wistar Rat
  6. Neuroprotective Effect of Crocin on Acrylamide-induced Cytotoxicity in PC12 cells
  7. Phototoxicity activity of Psoralea drupacea L. using Atremia salina bioassay system
  8. Preparation, Characterization and Evaluation of Sun Protective and Moisturizing Effects of Nanoliposomes Containing Safranal
  9. Study Of A Titumor Effect Of Metha Olic A D Aqueous Extracts Of Allium Stivum L. (Garlic) Cloves Usi G Potato Disc Bioassay
  10. The effect of crocin and safranal, constituents of saffron, against subacute effect of diazinon on hematological and genotoxicity indices in rats
  11. Alginate microspheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN induced partial protection and enhanced immune response against murine model of leishmaniasis
  12. A Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs
  13. Antioxidant activity of the essential oils of different parts of Juniperus excelsa M. Bieb. subsp. excelsa and J. excelsa M. Bieb. subsp. polycarpos (K. Koch) Takhtajan (Cupressaceae)
  14. Correlation between cathepsin D serum concentration and carotid intima-media thickness in hemodialysis patients.
  15. Comparison of physicomechanical properties of films prepared from organic solutions and aqueous dispersion of Eudragit RL
  16. Correlation between heat-shock protein 27 serum concentration and common carotid intima-media thickness in hemodialysis patients
  17. Effect of Zataria multiflora Bois L. on histamine (H1) receptor of guinea pig tracheal chains.
  18. Effects of Saffron (Crocus sativus L.) and its Active Constituent, Crocin, on Recognition and Spatial Memory after Chronic Cerebral Hypoperfusion in Rats
  19. Glutamate racemization and catabolism in Fusobacterium varium
  20. Immunization against leishmaniasis by PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN
  21. Pentoxifylline administration changes protein expression profile of coronary artery disease patients
  22. Prevalence of Exercise Induced Asthma in Female School Students
  23. Pharmacological Effects of Rosa Damascena
  24. Production of Ibuprofen Pellets Containing High Amount of Rate Retarding Eudragit RL Using PEG400 and Investigation of Their Physicomechanical Properties
  25. Pulmonary function tests and respiratory symptoms among smokers in the city of mashhad (north east of Iran)
  26. Quantitative LC Analysis of Cyclosporine A in Ocular Samples
  27. Synthesis of Novel 4-[1-(4-fluorobenzyl)-5-imidazolyl] Dihydropyridines and Studying their Effects on Rat Blood Pressure
  28. The effect of Nigella sativa alone, and in combination with dexamethasone, on tracheal muscle responsiveness and lung inflammation in sulfur mustard exposed guinea pigs
  29. The effect of Crocus sativus extract on human lymphocytes' cytokines and T helper 2/T helper 1 balance.
  30. The effect of carvacrol on muscarinic receptors of guinea-pig tracheal chains.
  31. The effect of Nigella sativa extract on tracheal responsiveness and lung inflammation in ovalbumin-sensitized guinea pigs.
  32. Antioxidant effects of the essential oils of different parts of platycladus orientalis L. (Franco) and their components
  33. Comparison of Valproic acid Clearance between Epileptic Patients and Patients with Acute Mania
  34. Clozapine Recognition via Molecularly Imprinted Polymers; Bulk Polymerization Versus Precipitation Method
  35. Preventive Effect of Vitamin B6 on Developmental Toxicity of Carbamazepine in Mice
  36. Teratogenic effects of HESA-A, a natural anticancer product from Iran, in mice
  37. Zataria multiflora Boiss and Carvacrol Affect beta(2)-Adrenoceptors of Guinea Pig Trachea
  38. Effect of Aqueous-Ethanolic Extract from Rosa damascena on Guinea Pig Isolated Heart
  39. Antioxidant and antimicrobial activity of methanol, dichloromethane, and ethyl acetate extracts of Scutellaria litwinowii
  40. Comparison of Chemical Composition of Achillea eriophora and A. wilhelmsii Grown in Wild and Cultivated Conditions in Iran
  41. Expression of Drug Pump Protein MRP2 in Lipopolysaccharide-Treated Rats and its Impact on the Disposition of Acetaminophen
  42. Identification of Spathulenol in Salvia mirzayanii and the Immunomodulatory Effects
  43. Improvement of cytotoxic and apoptogenic properties of crocin in cancer cell lines by its nanoliposomal form
  44. Liposome-linear polyethyleneimine- DNA Nanocomplexes for Gene Delivery: Preparation, Characterization and In Vitro Transfection Activity
  45. Effect of the two new calcium channel blockers mebudipine and dibudipine on vascular flow of isolated kidney of normal and diabetic rats
  46. Immunoinhibitory effect of teuclatriol a guaiane sesquiterpene from Salvia mirzayanii
  47. Antiviral and antimicrobial activity of Thymus transcaspicus essential oil
  48. New N-aryl-4-(methysulfony)aminobenzenesulfonamid es as selective COX-2 inhibitors
  49. Quantitative LC analysis of Methotrexate and its application in pharmacokinetic study of drug in rat serum samples
  50. Serum vitamin E concentration in Iranian population with angiography defined coronary artery disease
  51. Possible mechanism(s) of the relaxant effect of asafoetida (Ferula assa-foetida) oleo-gum-resin extract on guinea-pig tracheal smooth muscle
  52. Evaluation of nitric oxide or opioid receptors involvement in antinociceptive properties of silymarin
  53. Evaluation of RANKL/OPG Serum Concentration Ratio as a New Biomarker for Coronary Artery Calcification: A Pilot Study
  54. Degradation of Diclofenac in Molecularly Imprinted Polymer Submicron Particles by UV Light Irradiation and HCl Acid Treatment
  55. Effects of sage (Ocimun bacilicum) extract fractions on morphine withdrawal syndrome in mice

 

  • 2012 publications
  1. Virtual screening for finding novel COX-2 inhibitors as antitumor agents
  2. Effect of Erythropoietin on Serum Brain-derived Biomarkers after Carbon Monoxide Poisoning in Rats
  3. Effects of erythropoietin on electrocardiogram changes in carbon monoxide poisoning: An experimental study in rats
  4. Synthesis and Immunomodulation of Human Lymphocyte Proliferation and Cytokine (Interferon-gamma) Production of Four Novel Leflunomide Analogues
  5. Anti-nociceptive and Anti-inflammatory Effects of Cyanocobalamin (Vitamin B12) Against Acute and Chronic Pain and Inflammation in Mice
  6. Epilepsy drugs and effects on fetal development: Potential mechanisms
  7. The effect of granulocyte colony-stimulating factor administration on carbon monoxide neurotoxicity in rats
  8. Anti-cholinergic effect of Zataria multiflora Boiss on guinea pig tracheal chains
  9. The effect of vitamin E on pathological changes in kidney and liver of sulphur mustard-exposed guinea pigs
  10. The effect of the extract of Crocus sativus and its constituent safranal, on lung pathology and lung inflammation of ovalbumin sensitized guinea-pigs
  11. Inhibitory effect of Zataria multiflora Boiss and carvacrol on histamine (H1) receptors of guinea-pig tracheal chains
  12. Exercise induced bronchospasm in physically fit female students of Kerman University and their pulmonary function tests
  13. Relationship between Patient Demographic Characteristics, Valproic Acid Dosage and Clearance in Adult Iranian Patients
  14. Sonodynamic Therapy Using Protoporphyrin IX Conjugated to Gold Nanoparticles: An In Vivo Study on a Colon Tumor Model
  15. Determination of heavy metals in different honey brands from Iranian markets
  16. Nicotine Content of Domestic Cigarettes, Imported Cigarettes and Pipe Tobacco in Iran
  17. Acute and Subacute Toxicity of Safranal, a Constituent of Saffron, in Mice and Rats
  18. Effect of Linalool on Morphine Tolerance and Dependence in Mice
  19. Safranal: From an Aromatic Natural Product to a Rewarding Pharmacological Agent
  20. Safety Evaluation of Crocin (a constituent of saffron) Tablets in Healthy Volunteers
  21. Antioxidant Activity of Pistacia vera Fruits, Leaves and Gum Extracts
  22. Cardioprotective Effect of Saffron Extract and Safranal in Isoproterenol-Induced Myocardial Infarction in Wistar Rats
  23. Crocin Restores Hypotensive Effect of Subchronic Administration of Diazinon in Rats
  24. Development and Validation of HPLC Method for Determination of Crocetin, a constituent of Saffron, in Human Serum Samples
  25. Antinociceptive Evaluation Of Ceftriaxone And Minocycline Alone And In Combination In A Neuropathic Pain Model In Rat
  26. Effect of thymoquinone, a constituent of Nigella sativa L., on ischemia-reperfusion in rat skeletal muscle
  27. Effect of aqueous extract of Crocus sativus L. (saffron) stigma against subacute effect of diazinon on specific biomarkers in rats.
  28. In vitro insulin release from thermosensitive chitosan hydrogel
  29. Affinity-based target deconvolution of safranal
  30. Protective Effect of Silymarin against Acrolein-Induced Cardiotoxicity in Mice
  31. Suppression of MAPKAPK2 during mammalian hibernation
  32. Effects of granulocyte colony-stimulating factor on electrocardiogram changes after carbon monoxide poisoning in rats
  33. Development of a novel histone H1-based recombinant fusion peptide for targeted non-viral gene delivery
  34. Umbelliprenin is cytotoxic against QU-DB large cell lung cancer cell line but anti-proliferative against A549 adenocarcinoma cells
  35. The Effect of Lipopolymer Structure on the Transfection Efficiency of Hydrophobic Polyethylenimine-based Cationic Nanoliposomes
  36. beta-Galactosylated Alkyl-oligoamine Derivatives of Polyethylenimine Enhanced pDNA Delivery into Hepatic Cells with Reduced Toxicity
  37. Pentoxifylline decreases soluble CD40 ligand concentration and CD40 gene expression in coronary artery disease patients
  38. Evaluation of Curcumin Effects on Post-Operative Peritoneal Adhesion in Rats
  39. Determination of parathion, aldicarb, and thiobencarb in tap water and bottled mineral water in Mashhad, Iran
  40. In vitro Leishmanicidal activity of Calotropis gigantea and its fractions against Leishmania major
  41. Application of molecularly imprinted hydrogel for the preparation of lactose-free milk
  42. Preparation and Investigation of Sustained Drug Delivery Systems Using an Injectable, Thermosensitive, In Situ Forming Hydrogel Composed of PLGA-PEG-PLGA
  43. Development of a pH-responsive imprinted polymer for diclofenac and study of its binding properties in organic and aqueous media
  44. The potential effect of the extract of Crocus sativus and safranal on the total and differential white blood cells of ovalbumin-sensitized guinea pigs
  45. Tracheal responsiveness to methacholine and ovalbumin; and lung inflammation in guinea pigs exposed to inhaled lead after sensitization
  46. Respiratory symptoms and pulmonary function testes in lead exposed workers
  47. Evaluation of aqueous and ethanolic extracts of saffron, Crocus sativus L., and its constituents, safranal and crocin in allodynia and hyperalgesia induced by chronic constriction injury model of neuropathic pain in rats
  48. Anxiolytic and Hypnotic Effects of Aqueous and Ethanolic Extracts of Aerial Parts of Echium italicum L. in Mice
  49. Review Of Pharmacological And Toxicological Effects Of Nigella Sativa And Its Active Constituents
  50. Can We Accurately Assess Liver Fibrosis with Fibroscan (R) Using Fewer Valid Measurements?
  51. Prediction of Poor Outcome in Patients with Acute Liver Failure-Systematic Review of Prediction Models
  52. Effect of verapamil on bronchial goblet cells of asthma: An experimental study on sensitized animals
  53. Antiemetic activity of volatile oil from Mentha spicata and Mentha * piperita in chemotherapy-induced nausea and vomiting.
  54. Mucosal Adjuvant Potential of Quillaja saponins and Cross-linked Dextran Microspheres, Co-administered with Liposomes Encapsulated with Tetanus Toxoid
  55. Anticonvulsant effect of Berberis integerrima L. root extracts in mice
  56. Evaluation of RANKL/OPG Serum Concentration Ratio as a New Biomarker for Coronary Artery Calcification: A Pilot Study
  57. The Effect of Cationic Charge Density Change on Transfection Efficiency of Polyethylenimine
  58. The effects of pentoxifylline administration on NFΚB P50 transcription factor expression
  59. Plasmid DNA delivery into hepatocytes using a multifunctional nanocarrier based on sugar-conjugated polyethylenimine
  60. Preparation and analysis of a sustained drug delivery system by PLGA-PEG-PLGA triblock copolymers
  61. Controlled release of prednisolone acetate from molecularly imprinted hydrogel contact lenses
  62. Influence of sepsis on higher daily dose of amikacin pharmacokinetics in critically ill patients
  63. Evaluation Of The Association Between At(1)R1166c Polymorphism And The Incidence Of Cad And Cac Score In The Iranian Population
  64. Organic solution versus aqueous dispersion of Eudragit RS in preparation of sustained release microparticles of theophylline using spray drying

 

  • 2013 publications
  1. Cannabinoid System of the Lateral Septum in the Modulation of Anxiety-like Behaviors in Rats
  2. Traditional Chinese and Indian medicine in the treatment of opioid-dependence: a review
  3. Effect of the Zataria multiflora on systemic inflammation of experimental animals model of COPD.
  4. Protective effect of crocin on diazinon induced cardiotoxicity in rats in subchronic exposure
  5. Co-prescription of Gastroprotective Agents and Their Efficacy in Elderly Patients Taking Nonsteroidal Anti-inflammatory Drugs: A Systematic Review of Observational Studies
  6. Organic solution versus aqueous dispersion of Eudragit RS in preparation of sustained release microparticles of theophylline using spray drying
  7. Preparation of a Molecularly Imprinted Soft Contact Lens as a New Ocular Drug Delivery System for Dorzolamide
  8. Alkylcarboxylate Polyethylenimine-grafted Chitosans as Efficient Gene Vectors with Improved Gene Delivery Activity
  9. Crocetin Attenuates Spatial Learning Dysfunction and Hippocampal Injury in a Model of Vascular Dementia
  10. Effects of rutin on acrylamide-induced neurotoxicity
  11. Synthesis and molecular modeling of six novel monastrol analogues: evaluation of cytotoxicity and kinesin inhibitory activity against HeLa cell line
  12. Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus
  13. Proteomic screening of molecular targets of crocin
  14. Lead exposure affects inflammatory mediators, total and differential white blood cells in sensitized guinea pigs during and after sensitization
  15. Preparation and characterization and release properties of Eudragit RS based ibuprofen pellets prepared by extrusion spheronization: effect of binder type and concentration
  16. Effect of cyanocobalamin (vitamin B12) in the induction and expression of morphine tolerance and dependence in mice
  17. Antiemetic activity of volatile oil from Mentha spicata and Mentha x piperita in chemotherapy-induced nausea and vomiting
  18. Epirubicin loaded super paramagnetic iron oxide nanoparticle-aptamer bioconjugate for combined colon cancer therapy and imaging in vivo
  19. Preparation and Evaluation of Histamine Imprinted Polymer as a Selective Sorbent in Molecularly Imprinted Solid-Phase Extraction Coupled with High Performance Liquid Chromatography Analysis in Canned Fish
  20. Bioactivity assessment and toxicity of crocin: A comprehensive review
  21. Inter-observer and Intra-observer Agreement in Pathological Evaluation of Non-alcoholic Fatty Liver Disease Suspected Liver Biopsies
  22. Umbelliprenin induced production of IFN-gamma and TNF-alpha, and reduced IL-10, IL-4, Foxp3 and TGF-beta in a mouse model of lung cancer
  23. A study on druggability of MIA as a promising approach for inhibition of metastasis
  24. Arginine-rich hydrophobic polyethylenimine: Potent agent with simple components for nucleic acid delivery
  25. From rationally designed polymeric and peptidic systems to sophisticated gene delivery nano-vectors
  26. Non-covalent functionalization of single-walled carbon nanotubes with modified polyethyleneimines for efficient gene delivery
  27. Pentoxifylline Decreases Serum Level of Adhesion Molecules in Atherosclerosis Patients
  28. Synthesis, Anti-Inflammatory and Anti- Nociceptive Activities and Cytotoxic Effect of Novel Thiazolidin-4-ones Derivatives as Selective Cyclooxygenase (COX-2) Inhibitors
  29. Teratogenic Effects of Pregabalin in Mice
  30. Teratogenic Effects of Long Term Consumption of Potassium Benzoate on Eye Development in Balb/c Fetal Mice
  31. The Effects of Low Level Laser Therapy on the Expression of Collagen Type I Gene and Proliferation of Human Gingival Fibroblasts (Hgf3-Pi 53): in vitro Study
  32. Improvement of Physico-mechanical Properties of Partially Amorphous Acetaminophen Developed from Hydroalcoholic Solution Using Spray Drying Technique
  33. The Effect of Carvacrol on Serum Cytokines and Endothelin Levels of Ovalbumin Sensitized Guinea-Pigs
  34. Inter-individual Variability of Coumarin 7-hydroxylation (CYP2A6 activity) in an Iranian Population
  35. Effects of chronic crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats
  36. Failure of Intravenous Lipid Emulsion to Reduce Diazinon-induced Acute Toxicity: a Pilot Study in Rats
  37. Cytotoxic effects of crocin on MOLT-4 human leukemia cells
  38. Targeted delivery of Epirubicin to cancer cells by PEGylated A10 aptamer.
  39. Dummy Template Molecularly Imprinted Polymer for Omeprazole and the Study of Its Drug Binding and Release Properties
  40. Molecular weight-dependent genetic information transfer with disulfide-linked polyethylenimine-based nonviral vectors
  41. Preparation and characterisation of PLGA-PEG-PLGA nanospheres prepared with a new thermogelling method for insulin delivery
  42. Pyrimido 5,4-e tetrazolo 5,1-b 1,3,4 thiadiazines as a new heterocyclic system
  43. Extraction of Lycopene from Tomato Paste by Ursodeoxycholic Acid Using the Selective Inclusion Complex Method
  44. Targeted gene delivery with noncovalent electrostatic conjugates of sgc-8c aptamer and polyethylenimine
  45. Effect of carbamazepine on homocysteine serum level in pregnant mice and fetal malformations outcome
  46. Antihypertensive Effect of Celery Seed on Rat Blood Pressure in Chronic Administration
  47. Saffron: A Herbal Medicine of Third Millennium
  48. Saffron Reduced Toxic Effects of its Constituent, Safranal, in Acute and Subacute Toxicities in Rats
  49. The Effect of Chronic Administration of Saffron (Crocus sativus) Stigma Aqueous Extract on Systolic Blood Pressure in Rats
  50. Antioxidant Activity of Leaves and Fruits of Cultivated Conifers in Iran
  51. Gene Transfer Enhancement by Alkylcarboxylation of Poly(propylenimine)
  52. Evaluation of cyclosporine A eye penetration after administration of liposomal or conventional forms in animal model
  53. A novel label free cocaine assay based on aptamer-wrapped single-walled carbon nanotubes
  54. Tactile Learning within the Early Phase of Experimental Autoimmune Encephalomyelitis in Mice
  55. Hypotensive Effect of a Novel Dihydropyridine with Dual Calcium Channel Blocking and Angiotensin II Antagonistic Properties in a Rat Model
  56. Frequency and nature of drug-drug interactions in the intensive care unit
  57. The effect of intra-ventral hippocampus administration of TRPV1 agonist and antagonist on spatial learning and memory in male rats
  58. Serum Levels of Sodium Valproate in Patients Suffering from Bipolar Disorders: Comparing Acute and Maintenance Phases of Mania
  59. Assessment of Cytotoxic Properties of Safranal and Nanoliposomal Safranal in Various Cancer Cell Lines
  60. Avicenna's (Ibn Sina) the Canon of Medicine and Saffron (Crocus sativus): A Review
  61. Antitumor Activity of PEGylated Nanoliposomes Containing Crocin in Mice Bearing C26 Colon Carcinoma
  62. Promising effects of intravenous lipid emulsion as an antidote in acute tramadol poisoning
  63. Blood Bag emperature Monitoring System
  64. Web-site evaluation tools: a case study in reproductive health information.
  65. Attitudes and Experience of Dutch General Practitioners Regarding Computerized Clinical Decision Support
  66. The consequences of seniors seeking health information using the internet and other sources.
  67. Proteomic analysis of rat cerebral cortex following subchronic acrolein toxicity
  68. Effect of aqueous extract of Crocus sativus L. (saffron) stigma against subacute effect of diazinon on specific biomarkers in rats
  69. From assessment to improvement of elderly care in general practice using decision support to increase adherence to ACOVE quality indicators: study protocol for randomized control trial
  70. Improving stroke prevention in patients with atrial fibrillation
  71. Effect of carbamazepine on homocysteine serum level in pregnant mice and fetal abnormalities
  72. Effect of carbamazepine on homocysteine serum level in pregnant mice and fetal malformations outcome

 

  • 2014 publications
  1. Usability Evaluation of Laboratory and Radiology Information Systems Integrated into a Hospital Information System
  2. Umbelliprenin induced production of IFN-gamma and TNF-alpha, and reduced IL-10, IL-4, Foxp3 and TGF-beta in a mouse model of lung cancer
  3. Ultrasensitive detection of lead (II) based on fluorescent aptamer-functionalized carbon nanotubes
  4. The protective effect of Nigella sativa against liver injury: a review
  5. The impact of computerized decision aid on mode of delivery - a study protocol
  6. The effect of curcumin on some of traditional and non-traditional cardiovascular risk factors: A pilot randomized, double-blind, placebo-controlled trial
  7. The effect of chronic administration of safranal on systolic blood pressure in rats
  8. Targeted Gene Delivery to MCF-7 Cells Using Peptide-Conjugated Polyethylenimine
  9. Synthesis of AS1411-Aptamer-Conjugated CdTe Quantum Dots with High Fluorescence Strength for Probe Labeling Tumor Cells
  10. Synthesis and biological evaluation of novel pyridine derivatives as potential anticancer agents and phosphodiesterase-3 inhibitors
  11. Surelease or organic solution of ethylcellulose in preparation of sustained release theophylline micromatrices or matrices using spray drying technique
  12. Surelease as granulating liquid in preparation of sustained release matrices of ethylcellulose and theophylline
  13. Serum Osteopontin Concentrations in Relation to Coronary Artery Disease
  14. Sensitive and fast detection of tetracycline using an aptasensor
  15. Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid
  16. Review of Plants and Their Constituents in the Therapy of Cerebral Ischemia
  17. Review of Pharmacological Effects of Myrtus communis L. and its Active Constituents
  18. Relationship between serum cytokine and growth factor concentrations and coronary artery disease
  19. Rabbit nasal immunization against influenza by dry-powder form of chitosan nanospheres encapsulated with influenza whole virus and adjuvants
  20. Proteomics screening of molecular targets of granulocyte colony stimulating factor in the mouse brain and PC12 cell line
  21. Protective effects of the aqueous extract of Crocus sativus against ethylene glycol induced nephrolithiasis in rats
  22. Protective effect of crocin on diazinon induced vascular toxicity in subchronic exposure in rat aorta ex-vivo
  23. Promising dissolution enhancement effect of soluplus on crystallized celecoxib obtained through antisolvent precipitation and high pressure homogenization techniques
  24. Preparation, evaluation and application of diazinon imprinted polymers as the sorbent in molecularly imprinted solid-phase extraction and liquid chromatography analysis in cucumber and aqueous samples
  25. Preparation of Effective and Safe Gene Carriers by Grafting Alkyl Chains to Generation 5 Polypropyleneimine
  26. Preparation of a pH-sensitive pantoprazole-imprinted polymer and evaluation of its drug-binding and -releasing properties
  27. Preparation and study of tramadol imprinted micro-and nanoparticles by precipitation polymerization: Microwave irradiation and conventional heating method
  28. Preparation and in-vitro Transfection Efficiency Evaluation of Modified Cationic Liposome-polyethyleneimine-plasmid Nanocomplexes as a Novel Gene Carrier
  29. Preparation and Evaluation of Histamine Imprinted Polymer as a Selective Sorbent in Molecularly Imprinted Solid-Phase Extraction Coupled with High Performance Liquid Chromatography Analysis in Canned Fish
  30. Preparation and characterization of spray-dried powders intended for pulmonary delivery of Insulin with regard to the selection of excipients
  31. Preparation and characterization of celecoxib solid dispersions; comparison of poloxamer-188 and PVP-K30 as carriers
  32. Preparation and characterization of celecoxib dispersions in soluplus((R)): comparison of spray drying and conventional methods
  33. Photochemical Behavior of Sethoxydim in the Presence of Vegetable Oils
  34. Neuroprotective effect of thymoquinone in acrylamide-induced neurotoxicity in Wistar rats
  35. Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin - A mini-review
  36. Morphine Reduces Expression of TRPV1 Receptors in the Amygdala but not in the Hippocampus of Male Rats
  37. Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases
  38. Minocycline potentiates the anti-hyperalgesic effect of ceftriaxone in CCI-induced neuropathic pain in rats
  39. Linalool as a neuroprotective agent against acrylamide-induced neurotoxicity in Wistar rats
  40. Involvement of central TRPV1 receptors in pentylenetetrazole and amygdala-induced kindling in male rats
  41. Inter-observer and Intra-observer Agreement in Pathological Evaluation of Non-alcoholic Fatty Liver Disease Suspected Liver Biopsies
  42. Insecticidal activity of the essential oil of Thymus transcaspicus against Anopheles stephensi
  43. Inhibitory effects of teuclatriol, a sesquiterpene from salvia mirzayanii, on nuclear factor-kappa B activation and expression of inflammatory mediators
  44. Inhibitory effect of Crocus sativus L. ethanol extract on adjuvant-induced arthritis
  45. Inhibitory Effect of Berberis vulgaris Aqueous Extract on Acquisition and Reinstatement Effects of Morphine in Conditioned Place Preferences (CPP) in Mice
  46. In vitro protective effects of Scutellaria litwinowii root extract against H2O2-induced DNA damage and cytotoxicity
  47. Health information-seeking behavior of seniors who use the internet: A survey
  48. Haloperidol imprinted polymer: preparation, evaluation, and application for drug assay in brain tissue
  49. Glutathione-S-Transferase M1 and T1 Null Genotypes Are Associated with Hypertension Risk: A Systematic Review and Meta-Analysis of 12 Studies
  50. From assessment to improvement of elderly care in general practice using decision support to increase adherence to ACOVE quality indicators: study protocol for randomized control trial
  51. Evaluation of Protein Ubiquitylation in Heart Tissue of Rats Exposed to Diazinon (an Organophosphate Insecticide) and Crocin (an Active Saffron Ingredient): Role of HIF-1alpha
  52. Evaluation of leishmanicidal effect of Euphorbia erythadenia extract by in vitro leshmanicidal assay using promastigotes of Leishmania major
  53. Evaluation of intravenous lipid emulsion on haloperidol-induced hypotension in rabbits
  54. Evaluation of 11 scoring functions performance on matrix metalloproteinases
  55. Evaluating the Effects and Safety of Intravenous Lipid Emulsion on Haloperidol-Induced Neurotoxicity in Rabbit
  56. Epithelial cell adhesion molecule aptamer conjugated PEG-PLGA nanopolymersomes for targeted delivery of doxorubicin to human breast adenocarcinoma cell line in vitro
  57. Efficacy of orally administered montmorillonite for acute iron poisoning detoxification in rat
  58. Effects of Intraperitoneal Thymoquinone on Chronic Neuropathic Pain in Rats
  59. Effects of chronic crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats
  60. Effect of Nigella sativa on ischemia-reperfusion induced rat kidney damage
  61. Effect of Nigella sativa fixed oil on ethanol toxicity in rats
  62. Effect Of Diabetes Mellitus On The Metabolism Of Drugs And Toxins
  63. Effect of cyanocobalamin (vitamin B12) in the induction and expression of morphine tolerance and dependence in mice
  64. Effect of Crocus sativus L. (Saffron) on Coagulation and Anticoagulation Systems in Healthy Volunteers
  65. Effect of aqueous extract of Crocus sativus L. (saffron) stigma against subacute effect of diazinon on specific biomarkers in rats
  66. Effect of aqueous and ethanolic extracts of Pimpinella anisum L. seeds on milk production in rats
  67. Effect of apple cider Vinegar on blood glucose level in diabetic mice (Article)
  68. Drug-drug interactions in inpatient and outpatient settings in Iran: a systematic review of the literature
  69. Development of ocular drug delivery systems using molecularly imprinted soft contact lenses
  70. Development of computerized clinical decision support to assist in detecting and preventing delirium in the hospital setting (Conference Paper)
  71. Design and fabrication of an aptasensor for chloramphenicol based on energy transfer of CdTe quantum dots to graphene oxide sheet
  72. Delayed combination therapy of local brain hypothermia and decompressive craniectomy on acute stroke outcome in rat
  73. Crocin, the main active saffron constituent, as an adjunctive treatment in major depressive disorder: A randomized, double-blind, placebo-controlled, pilot clinical trial
  74. Crocin improves lipid dysregulation in subacute diazinon exposure through ERK1/2 pathway in rat liver
  75. Crocin effects on human myeloma cells regarding intracellular redox state, DNA fragmentation, and apoptosis or necrosis profile
  76. Conformational switch of insulin-binding aptamer into G-quadruplex induced by K(+) and Na(+): an experimental and theoretical approach
  77. Comparing various techniques to produce micro/nanoparticles for enhancing the dissolution of celecoxib containing PVP
  78. Comparative evaluation of polymersome versus micelle structures as vehicles for the controlled release of drugs
  79. Clinical Applications of Saffron (Crocus sativus) and its Constituents: A Review
  80. Chrysin reduced acrylamide-induced neurotoxicity in both in vitro and in vivo assessments
  81. Central administration of GPR55 receptor agonist and antagonist modulates anxiety-related behaviors in rats
  82. Ceftriaxone, a Beta-Lactam Antibiotic, Modulates Apoptosis Pathways and Oxidative Stress in a Rat Model of Neuropathic Pain
  83. Carum induced hypothyroidism: an interesting observation and an experiment
  84. Brimonidine imprinted hydrogels and evaluation of their binding and releasing properties as new ocular drug delivery systems
  85. Blood bag temperature monitoring system
  86. Black cumin (Nigella sativa) and its constituent (thymoquinone): a review on antimicrobial effects
  87. Attenuation of oxidative stress, inflammation and apoptosis by ethanolic and aqueous extracts of Crocus sativus L. stigma after chronic constriction injury of rats
  88. Aptamer Biosensor for Selective and Rapid Determination of Insulin
  89. Antioxidant and Anti-Inflammatory Properties of the Citrus Flavonoids Hesperidin and Hesperetin: An Updated Review of their Molecular Mechanisms and Experimental Models
  90. Antilithiatic effects of crocin on ethylene glycol-induced lithiasis in rats
  91. Antidepressant Effect of Crocus sativus Aqueous Extract and its Effect on CREB, BDNF, and VGF Transcript and Protein Levels in Rat Hippocampus
  92. An imbalance in serum concentrations of inflammatory and anti-inflammatory cytokines in hypertension
  93. Alteration of protein profile in rat liver of animals exposed to subacute diazinon: A proteomic approach
  94. A study on druggability of MIA as a promising approach for inhibition of metastasis
  95. A review of the effects of Nigella sativa L. and its constituent, thymoquinone, in metabolic syndrome
  96. A Predictive HQSAR Model for a Series of Tricycle Core Containing MMP-12 Inhibitors with Dibenzofuran Ring
  97. A New Versatile Route to the Synthesis of a Novel Series of Highly Substituted 1,1 '-Carbonylbispyrazole Derivatives
  98. A fluorescent aptasensor for potassium ion detection-based triple-helix molecular switch
  99. A diagnostic model for cirrhosis in patients with non-alcoholic fatty liver disease: an artificial neural network approach
     

100. 8-pCPT, an Epac activator, impairs conditioned place preference based on nucleus accumbens amphetamine in rats

 

  • Books

Row

Title

Author

Published Date

1

Drug Bio-Pharmacy and Kinetics

Dr. Mohammad Hassanzadeh Khayat

1992

2

Instrumental Analysis Methods

Dr. Mohammad Hassanzadeh Khayat

2000

3

Pediatric Herbal Therapy

Dr. Mohammad Ramazani

2003

4

Side Effects of Medicinal Herbs (2nd edition)

Dr. Mohsen Tafaqodi

2004

5

Side Effects of Medicinal Herbs (1st edition)

Dr. Tafaqodi – Dr. Amiri

2004

6

Pharmaceutics (Science of Designing Medicinal Forms)

Dr. Afrasiabi – Dr. Tafaqodi – Dr. Sajjadi – Dr. Sadeqi

2005

7

Side Effects of Medicinal Herbs (1st edition)

Dr. Tafaqodi – Dr. Reza Amiri

2006

8

Side Effects of Medicinal Herbs (3rd edition)

Dr. Hosseinzadeh – Dr. Tafaqodi

2006

9

Pharmaceutics (2nd edition)

Dr. Afrasiabi – Dr. Tafaqodi ….

2006

10

Medicinal Biotechnology: Methods of Procuring and Medicinal Products of Biotechnology

Mohammad Ramazani

2007

11

Pediatric Herbal Therapy

Dr. Mohammad Ramazani

2008

12

Laboratory Guide to Molecular Biology

Dr. Ramazani – Dr. Mosafa – Dr. Parhiz – Dr. Montazeri

2009

13

Pharmaceutics: Science of Designing Medicinal Forms

Translators: Dr. Afrasiabi…

2010

14

The ABCs of Diabetes

Dr. Seyed Ahmad Mohajeri – Dr. Hosseinzadeh

2011

15

The Science of Designing Medicinal Forms

Dr. Afrasiabi

2014

 

             

 

ü  Theses

 

Dr. Imen Shahidi

Effects of Dexrazoxane on aluminum posphide cardiotoxicity in rats

Effects of curcumin on prevention of under chronic cardiovascular damages resulting from Bisphenol A in rats

Protective effects of alcohol extract of lemon verbena leaves and verbascoside effective material on indomethacin-induced peptic ulcer in rat

Protective effect of lemon verbena leaf aqueous extract on indomethacin-induced peptic ulcer in rat

Effects of acute Montmorillonite in acute lithium carbonate–induced toxicity in rat

Dr. Ramazani

DNA aptamer isolation for specific identification of PD-L1(CD274) and performance review

Targeted delivery of irinotecan via Aptamer-PEG-acetylated carboxymethyl cellulose complex to colorectal cancer cells

Electrospun nanofibers containing BMP-2 liposomal peptide to increase mesenchymal stem cell differentiation to bone

PLGA-based nanoparticles loaded with doxorubicin and targeted using PNC-27 peptide as a targeted anti-cancer system

Evaluation of targeted pharmaceuticals to breast cancer cells resistant to MCF/7MX drug using ABCG2 specific aptamer transporter

Effects of crocin and crocetin substances extracted from saffron on mesenchymal cell differentiation in bone cells

Effects of saffron-extracted crocetin and PLGA nanoparticles containing crocetin on incidence of multi-drug resistance phenotype

Procurement of antigen-containing exosomal nanocarriers for tumor treatment

Dr. Abnoos

DNA aptamer isolation for specific identification of PD-L1(CD274) and performance review

Carbon paste electrode-based electrochemical sensors modified using polymer molecule framework nanoparticles for determining Diazinon dosage

Targeted delivery of irinotecan via Aptamer-PEG-acetylated carboxymethyl cellulose complex to colorectal cancer cells

Evaluation of targeted pharmaceuticals to breast cancer cells resistant to MCF/7MX drug using ABCG2 specific aptamer transporter

PLGA-based nanoparticles loaded with doxorubicin and targeted using PNC-27 peptide as a targeted anti-cancer system

Procurement of antigen-containing exosomal nanocarriers for tumor treatment

Dr. Mehri

Effects of tropisetron on oxazaphosphorine-induced hemorrhagic cystic (cyclophosphamide or ifosfamide) in rat

Dr. Hosseinzadeh

Mechanism review of protective effects of crocin on cell toxicity resulting from oxidative stress in isolated hepatocytes in rat

Effects of crocin on human lymphocyte proliferation and Thelper1 and Thelper2 balance

Protective effects of Q10 co-enzyme on acrylamide-induced neurotoxicity in in vivo and in vitro models

Effects of safranal on metabolic disorders resulting from olanzapine consumption in rat

Anti-depressant effects of grape seed extract and resveratrol on postpartum forced swimming and depression model in mice

Effects of crocin on inducing phenotype switching of macrophages to anti-inflammatory M2 state

Effects of thymoquinone on D-galactose induced aging model in rat: memory disorders and its mechanisms

Effects of crocin on nerve damage induced by D-galactose induced aging model in cellular (SH-SS5Y) and animal (rat) environment

Anti-depressant effect of aqueous and ethanol extracts of lemon verbena leaves and its primary substance, verbascoside, on postpartum forced swimming and depression model in mice

Dr. Leila Etemad

Effects of cinnamic aldehyde on methamphetamine-induced nerve damage in PC12 cell

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

in vivo evaluation of aromatase enzyme inhibition using a new composition of 4-(1-imidazole-1-Il)methyl-2-4-methoxy-phenyl benzo quinoline in rat

Anticonvulsant effects of Suvorexant in mice

Effects of acute Montmorillonite on acute lithium carbonate-induced toxicity in rat

Effects of curcumin nanomicelles on phosphine-induced cell damage in HepG2 cell

Effects of pregabalin on nerve evolution using mouse embryonic stem cells

Dr. Seyed Adel Moalem

Effects of cinnamic aldehyde on methamphetamine-induced cell damage in PC12 cell

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

Effects of acute Montmorillonite on acute lithium carbonate-induced toxicity in rat

Effects of pregabalin on nerve evolution using mouse embryonic stem cells

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with potential biomarkers effecting atherosclerosis in patients suffering from chronic cardiac ischemia

Dr. Roohbakhsh

Effects of flavonoid dihydromirestin on expression and acquisition of CPP and symptoms of morphine-induced addiction in mice

Dr. Saeed Islami

 

Anti-depressant effects of saffron stigma in pregnant women suffering from postpartum depression

Anti-depressant effects of saffron stigma tablets on pregnant women suffering from non-major postpartum depression

Study on the relationship between NSAIDS consumption and gastrointestinal bleeding in patients with upper gastrointestinal bleeding referring to Qaem Hospital during 2014

Rational prescription of clozapine and prevalence of agranulocytosis in a sample from Ibn Sina Psychiatry Hospital of Mashhad.

Investigation of doctors prescribing behavior pregnant mothers regarding insurance prescriptions in Razavi Khorasan Province in order to assess inappropriate prescriptions of drugs during pregnancy and establish localized drug prescription instructions for pregnancy consistent with national status.

Relationship between anxiety and educational performance in Mashhad Pharmacy School students

Dr. Mohammad Hasanzadeh Khayat

Carbon paste electrode-based electrochemical sensors modified using polymer molecule framework nanoparticles for determining Diazinon dosage

 

Evaluation of serum concentrations of neopterin as an individual cardiovascular biomarker in patients suffering from coronary artery diseases

Amount of ethanol and methanol in alcohol-free beer brands in Iranian markets

Dr. Afrasiabi

Effects of different types and concentrations of plasticizers on characteristics of microcapsules from three different ethyl cellulose viscosities containing sodium diclophenac procured using emulsion-evaporation of solvent method

Procurement and evaluation of slow-release metoprolol microcapsules using eudragit RS polymers and ethyl cellulose

Performance review of Carr’s Index and Hausner Ratio for determining characteristics of powder flows and evaluating the effects of factors such as powder particle size and type and amount of glidant on these indicators

Comparison of the effects of nerolidol and oleic acid as an enhancer for skin permeability of diclophenac D –ethyl amine in patches provided using R-L eudragit base

Dr. Amir Hooshang Mohamadpoor

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

Evaluation of serum concentrations of neopterin as an individual cardiovascular biomarker in patients suffering from coronary artery diseases

Effects of topical creams containing honey and aloe vera in treatment of radiotherapy-induced dermatitis in breast cancer patients

Dr. Seyed Ahmad Mohajeri

Evaluation of vitamin A suppositories for vaginal use

Protective effects of crocin and corcetin against hyperglycemic damage in retina cells

Procurement of fluorometholone molecular molded hydrogels as ocular drug delivery systems and investigation of binding properties of the drug and its release into the environment

 

 

 

 

ü  Main activities

  • Screening teratogenic effects of chemical substances and medicinal herbs
  • Analytical toxicology of nutrients
  • Synthesis and analysis of drug derivatives
  • Basic researches on modern drug delivery systems (liposomes, nanospheres)
  • Isolation and purification of active herbal compounds
  • Investigating pharmacological effects of medicinal herbs and their synthetic derivatives

 

ü  Equipment:

 

  • Department of Nanomedicine

Supervisor: Dr. Mohammadreza Ramazani (Professor of Medicinal Biotechnology)

Equipment include: MPLC, refrigerated centrifuge, optical microscope, UV cabinet, vacuum centrifuge, ELISA reader, freeze dryer, all equipment required for column chromatography and TLC, sonicator, solvent removal device, and soxhlet device. Four computers with high-speed internet along with scanner and printer.

 

  • Department of Analysis

Supervisor: Dr. Mohammad Hassanzadeh Khayat (Professor of Medicinal Chemistry)

Equipment include: UV-VIS spectrophotometer, infra-red spectrophotometer, spectrofluorimeter device, high performance liquid chromatography device (HPLC) for analysis of different substances (qualitatively and quantitatively). 2 computers with internet access.

 

  • Department of Pharmacodynamics

Supervisor: Dr. Hossein Hosseinzadeh (Professor of Pharmacology)

Equipment include: HPLC device, Power Lab device, solvent removal device, hot plate, water maze (MWM), dry heater, oven, microscope with computer connective camera, centrifuge, digital scale, stereotaxy, etc.  Four computers with high-speed internet and one printer.

 

  • Department of Toxicology and Teratology

Supervisor: Dr. Seyed Adel Moalem (Professor of Toxicology)

Equipment include: tom mice fetus and organ culture device, several stereomicroscopes and digital imaging system for investigating fetal abnormalities, microtome, laminar hood, CO2 incubator and invert microscopes for cell culture, ELISA device, spectrophotometer, PCR gradient device, gel sequencing device, electrophoresis device for studying DNA, RNA, and proteins, and liquid nitrogen tanks for long-term preservation of cells. Two computers with high-speed internet along with two printers.



 

       

  

 

 

 

 
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