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Dr . Jamal Shamsara
Assistant Professor of Pharmaceutical Biotechnology
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Address: Tel: 051 37112470 Fax: 051 37112596
shamsaraj[at]mums.ac.ir j_shamsara[at]yahoo.com Updated at: |
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und Educational Background |
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2000-2006 Pharmacy Pharm. D. MUMS |
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2006-2011 Pharmaceutical Biotechnology Ph.D. MUMS |
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Research Interests |
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Virtual screening (structure based and ligand based) |
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QSAR studies |
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Structural bioinformatics |
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Molecular medicine |
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Publications |
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Ramezani, M and Shamsara, J. Application of DPD in the design of polymeric nano-micelles as drug carriers. Journal of Molecular Graphics and Modelling. (2016) 66,1-8. |
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Shamsara, J. CDocker: a tool for performing cross-docking using Autodock Vina. Springerplus. (2016) |
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Shamsara, J and Shahir-Sadr A. Developing a CoMSIA model for inhibition of COX-2 by resveratrol derivatives. Iranian journal of Pharmaceutical Research. (2016) In press. |
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Ramezani, M and Shamsara, J. A Cross-Docking Study on Matrix Metalloproteinase Family. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. (2016) 14, 1-8 |
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Shamsara, J. Considering rotatability of hydroxyl groups for the active site residues of MMP-13 in retrospective virtual screening campaigns. The Open Medicinal Chemistry Journal. (2016), 10: 1-6. |
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Gholami, O and Shamsara, J. Comparison of the cytotoxic effects of umbelliprenin and auraptene. International Journal of Pharmacy and Pharmaceutical Sciences. (2015) 8 (1). |
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Hadizadeh F., Shamsara J. Receptor-based 3D-QSAR approach to find selectivity features of flexible similar binding sites: case study on MMP-12/MMP-13. International Journal of Bioinformatics Research and Applications (2015) 11 (4): 326-346. |
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Shamsara J. Evaluation of 11 Scoring Functions Performance on Matrix Metalloproteinases. International Journal of Medicinal Chemistry (2014) 2014. |
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Shamsara J and Shahir-Sadr A. A Predictive HQSAR Model for a Series of Tricycle Core Containing MMP-12 Inhibitors with Dibenzofuran Ring. International Journal of Medicinal Chemistry (2014) 2014. |
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1Shamsara J. A study on druggability of MIA as a promising approach for inhibition of metastasis. International Journal of Computational Biology and Drug Design (2014) 7: 80-95. |
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Mohammadpour AH, Nazemian F, Khaiat MH, Tafaghodi M, Salari P, Charkazi S, Naghibi M and Shamsara J. Evaluation of the effect of pentoxifylline on erythropoietin-resistant anemia in hemodialysis patients. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (2014) 25: 73-78. |
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Mohammadpour AH, Falsoleiman H, Shamsara J, Abadi GA, Rasooli R and Ramezani M. Pentoxifylline decreases serum level of adhesion molecules in atherosclerosis patients. Iranian Biomedical Journal (2014) 18: 23-27. |
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Mohammadpour AH, Nazemian F, Shamsara J, Baf M, Ghorbani M and Moallem SA. Effects of omega-3 administration on concentration of serum inflammatory makers in renal transplant recipient. African Journal of Pharmacy and Pharmacology (2013) 7: 2021-2024. |
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Mohammadpour AH, Moallem SA, Bafandegan M, Shamsara J and Nazemian F. Effects of omega-3 administration on homocysteine serum concentration in renal transplant recipient. Journal of Pharmaceutical Care (2013) 1: 25-28. |
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Shamsara J, Mohammadpour AH, Behravan J, Falsoleiman H and Ramezani M. Pentoxifylline decreases soluble CD40 ligand concentration and CD40 gene expression in coronary artery disease patients. Immunopharmacology and Immunotoxicology (2012) 34: 523-529. |
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Shamsara J, Behravan J, Falsoleiman H, Mohammadpour AH and Ramezani M. The effects of pentoxifylline administration on NFKB P50 transcription factor expression. ARYA Atherosclerosis (2012) 7: 133-137. |
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Mohammadpour AH, Shamsara J, Nazemi S, Ghadirzadeh S, Shahsavand S and Ramezani M. Evaluation of RANKL/OPG serum concentration ratio as a new biomarker for coronary artery calcification: a pilot study. Thrombosis (2012) 2012. |
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Mohammadpour AH, Nazemi S, Foroughi M, Ghorbani M, Shamsara J and Behravan J. Evaluation of the association between AT 1R1166C polymorphism and the incidence of cad and CAC score in the Iranian population. Archives of Biological Sciences (2012) 64: 401-408. |
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Moallem SA, Hadizadeh F, Abadi FA, Shahraki M and Shamsara J. Synthesis and evaluation of pyridinyltriazoles as inhibitors of p38 MAP kinase. Iranian Journal of Basic Medical Sciences (2012) 15: 945-950. |
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Shamsara J, Behravan J, Falsoleiman H, Mohammadpour AH, Rendeirs J and Ramezani M. Pentoxifylline administration changes protein expression profile of coronary artery disease patients. Gene (2011) 487: 107-111. |
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Ramezani M, Nazemian F, Shamsara J, Koohrokhi R and Mohammadpour AH. Effect of Omega-3 Fatty Acids on Plasma Level of 8-Isoprostane in Kidney Transplant Patients. Journal of Renal Nutrition (2011) 21: 196-199. |
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Mohammadpour N, Elyasi S, Vahdati N, Mohammadpour AH and Shamsara J. A review on therapeutic drug monitoring of immunosuppressant drugs. Iranian Journal of Basic Medical Sciences (2011) 14: 485-498. |
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Mohammadpour AH, Nazemian F, Moallem SA, Alamdaran SA, Asad-Abadi E and Shamsara J. Correlation between heat-shock protein 27 serum concentration and common carotid intima-media thickness in hemodialysis patients. Iranian Journal of Kidney Diseases (2011) 5: 260-266. |
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Mohammadpour AH, Foroughipour M, Azarpazhooh MR, Khayat MH, Rezaee S, Aghebati T and Shamsara J. Comparison of valproic acid clearance between epileptic patients and patients with acute mania. Iranian Journal of Basic Medical Sciences (2011) 14: 546-550. |
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Moallem SA, Nazemian F, Eliasi S, Alamdaran SA, Shamsara J and Mohammadpour AH. Correlation between cathepsin D serum concentration and carotid intima-media thickness in hemodialysis patients. International Urology and Nephrology (2011) 43: 841-848. |
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Lotfi M, Afsharnezhad S, Raziee HR, Ghaffarzadegan K, Sharif S, Shamsara J, Lary S and Behravan J. Immunohistochemical assessment of MGMT expression and p53 mutation in glioblastoma multiforme. Tumori (2011) 97: 104-108. |
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Nazemian F, Karimi G, Moatamedi M, Charkazi S, Shamsara J and Mohammadpour AH. Effect of silymarin administration on TNF-α serum concentration in peritoneal dialysis patients. Phytotherapy Research (2010) 24: 1654-1657. |
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Mohammadpour A, Ramezani M, Nazemi S, Falsoleiman H, Shamsara J and Ghadirzadeh S. RANKL/OPG serum concentration ratio as a new biomarker for coronary artery calcification. in EUROPEAN HEART JOURNAL. 2010. OXFORD UNIV PRESS GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND. |
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Shamsara J, Sharif S, Afsharnezhad S, Lotfi M, Raziee HR, Ghaffarzadegan K, Moradi A, Rahighi S and Behravan J. Association between MGMT promoter hypermethylation and p53 mutation in glioblastoma. Cancer Investigation (2009) 27: 825-829. |
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Shamsara J, Ramezani M and Mohammadpour AH. The RANKL: Osteoprotegerin (OPG) ratio as a new biomarker for coronary artery disease. Iranian Journal of Medical Hypotheses and Ideas (2009) 3. |
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Shamsara J, Ramezani M and Mohammadpour AH. Curcumin as a novel plaque stabilizing agent in prevention of acute coronary syndrome. Iranian Journal of Medical Hypotheses and Ideas (2009) 3. |
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Shamsara J, Ramezani M and Mohammadpoor AH. Why homocysteine-lowering therapy does not have beneficial effects on patients with cardiovascular disease? Bioscience Hypotheses (2009) 2: 13-15. |
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Roohbakhsh A, Shamsara J, Khayyat MH and Karimi G. Inhibition of xanthine oxidase by some Iranian plant remedies used for gout. Pharmacologyonline (2009) 3: 1031-1036. |
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Foroughipour M, Mohammadpour AH, Vahdati Mashhadian N, Hasanzadeh KM, Azarpazhouh MR, Mokhber N, Aghebati T and Shamsara J. Therapeutic drug monitoring of valproic acid in patients with monotherapy at steady state. Iranian Journal of Basic Medical Sciences (2009). |
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Hosseinzadeh H, Jaafari MR and Shamsara J. Selective inhibitory effect of adenosine A1 receptor agonists on the proliferation of human tumor cell lines. Iran Biomed J (2008) 12: 203-8. |
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Presentations |
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Honors & Awards |
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Members hip Membership |
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National Foundation of Exceptional Talents (Bonyad-e Melli-e Nokhbegan, BMN) |
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Administrative Responsibilities |
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Other Skills |
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Teaching: Practical advanced medicinal chemistry Pharmacy training course Computational drug design (workshop) Homology Modeling (workshop)
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Google Scholar profile: https://scholar.google.com/citations?user=VX32ZGEAAAAJ&hl=en
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PubMed: http://www.ncbi.nlm.nih.gov/pubmed/?term=Jamal+Shamsara |
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