Pharmaceutical Research Center

Dr. Mohammadpour

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Dr Amir Hooshang Mohammadpour

 

 

 

Professor of  Clinical Pharmacy

        [at]mums.ac.ir
[at]yahoo.com

 

Address: School of Pharmacy, Mashhad University of Medical Sciences

Tel: +98 5138823255

Fax: +98 5138823251

 

Mohamadpoorah@ mums.ac.ir

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                                                       und Educational Background 

1999  Pharm D, School of Pharmacy, Ahvaz University of Medical Sciences, Iran

 

2004  Board Certified Clinical Pharmacy ,School of Pharmacy, Tehran University of Medical Sciences, Iran

 

2012-2013  Fellowship of Clinical Pharmacokinetic  , School of Pharmacy, University of Rhode Island, USA

 

                                                                   Research Interests

Clinical trials

 Clinical Pharmacokinetic

 Drug Use Evaluation

 

                                                                       Publications

1-     Seyedeh Pardis Jahanbakhsh, Ali Akhondpour Manteghi, Seyed Ahmad Emamic,Saman Mahyaria, Beheshteh Gholampourd, Amir Hooshang Mohammadpour,,Amir hossein Sahebkare. “ Evaluation of the efficacy of Withania somnifera (Ashwagandha) root extract in patients with obsessive-compulsive disorder: A randomized double-blind placebo-controlled trial.” Complementary Therapies in Medicine 27 (2016) 25–29

 

2-     Saman Mahyari , Behnam Mahyari , Seyed Ahmad Emami , Bizhan Malaekeh-Nikouei , Seyedeh Pardis Jahanbakhsh , Amirhossein Sahebkar ,Amir Hooshang Mohammadpour “ Evaluation of the efficacy of a polyherbal mouthwash containing Zingiber officinale, Rosmarinus officinalis and Calendula officinalis extracts in patients with gingivitis: A randomized double-blind placebo-controlled trial “  Complementary

 

Therapies in Clinical Practice 22 (2016) 93-98

 

3-      Mahmoud Hashemzaei, B. Saeed Keykha, C. Fatemeh Shahraki, D. Amir hooshang Mohammadpour and E. Kaveh Tabrizian” EFFECTS OF MAGNESIUM SULFATE ON THE ACQUISITION AND REINSTATEMENT OF MORPHINE-INDUCED CONDITIONED PLACE PREFERENCE IN MICE” J Fundam Appl Sci. 2016, 8(2S), 112-123

 

4-     Seyed Adel Moallem , Amir Hooshang Mohamadpour , Khalil Abnous , Mojtaba Sankian , Hamid Reza Sadeghnia , Aristidis Tsatsakis , Shabnam Shahsavan. “Erythropoietin in the treatment of carbon monoxide neurotoxicity in rat” Food and Chemical Toxicology 86 (2015) 56-64

 

5-     Mitra Asgharian Rezaee, Amir Hooshang Mohammadpour, Mohsen Imenshahidi,Mahmoud Mahmoudi, Mojtaba Sankian, Konstantinos Tsarouhas, Andreas Tsakalof,Aristidis Micheal Tsatsakis, Seyed Adel Moallem “Protective effect of erythropoietin on myocardial apoptosis in rats exposed to carbon monoxide ” Life Sciences 148 (2016) 118–124

6-     Tamara Aghebati, Ali Badiee, Amir Hooshang Mohammadpour, Mohammad Afshar, Mahmoud Reza Jaafari, Khalil Abnous, Sobhan Issazadeh, Saeed Hashemzadeh,Mohammad Zareh, Haydeh Hashemizadeh, Saeed Nazemig “Anti-atherosclerosis effect of different doses of CETP vaccine in rabbit model of atherosclerosis” Biomedicine & Pharmacotherapy ; 81 (2016) 468–473

 

7-    Hashemzaei M, Imen Shahidi M, Moallem SA, Abnous K, Ghorbani M, Mohamadpour AH“Modulation of JAK2, STAT3 and Akt1 proteins by granulocyte colony stimulating factor following carbon monoxide poisoning in male rat” Drug Chem Toxicol. 2016 Jan 25:1-5

 

8-     Maryam Ghorbani, Amir Hooshang Mohammadpour, Khalil Abnous, Ahmad Reza Movassaghi, Javad Raouf Sarshoori, Shabnam Shahsavand, Mahmoud Hashemzaei andSeyed Adel Moallem “G-CSF administration attenuates brain injury in rats following carbon monoxide poisoning via different mechanisms” Environ Toxicol. 2015 Oct 27. doi: 10.1002/tox.22210. [Epub ahead of print

 

 

9-       PARASTOO MIRZABEIGIA, AMIR HOOSHANG MOHAMMADPOURB, MOJTABA SALARIFARC, KHEIROLLAH GHOLAMIA, MOJTABA MOJTAHEDZADEHA AND MOHAMMAD REZA JAVADIA . “The Effect of Curcumin on some of Traditional andNon-traditional Cardiovascular Risk Factors: A Pilot Randomized, Double-blind, Placebo-controlled Trial” . Iranian Journal of Pharmaceutical Research (2015), 14 (2): 479-486

 

 

 

10-  ABOUBAKR RAHMANI, AMIR HOOSHANG MOHAMMADPOUR, ADELEH SAHEBNASAGH, SEYED AHMAD MOHAJERI”  Haloperidol imprinted polymer: preparation, evaluation, and application for drug assay in brain tissue” . Anal Bioanal Chem (2014) 406:7729–7739

 

11-  SEPIDEH ELYASIA, HOSSEIN KHALILIB*, SIMIN DASHTI-KHAVIDAKIB, HAMID EMADI-KOOCHAKC,AMIRHOOSHANG MOHAMMADPOURA AND ALIREZA ABDOLLAHID   “Elevated Vancomycin Trough Concentration:Increased Efficacy and/or Toxicity?” Iranian Journal of Pharmaceutical Research (2014), 13 (4): 1241-1247

 

12-  MARYAM VAHABZADEH , AMIR-HOUSHANG MOHAMMADPOUR “Effect of Diabetes Mellitus on the Metabolism of Drugs and Toxins” J Clin Toxicol 2015, 5:2

 

 

13-  Ali Gholamzadeh; Sara Amini ; Amir Hooshang Mohammadpour;Maryam Vahabzadeh; Amir Farjam Fazelifar; Afsoon Fazlinezhad; Mashalla Dehghani; Mohsen Moohebati; Mostafa Dastani; Bizhan Malaekeh- Nikouie, ; Homa Falsoleiman“Erythropoietin reduces post-PCI arrhythmias in patients with ST elevation myocardial infarction” Journal of Cardiovascular Pharmacology , 65(6):555-561

 

 

14-  Amir Hooshang Mohamadpour,a Leila Abdolrahmani,a Hamed Mirzaei,b Amirhosein Sahebkar,c Mohsen Moohebati,d Maryam Ghorbani,e Gordon A. Ferns,f and Majid Ghayour-Mobarhan “Serum Osteopontin Concentrations in Relation to Coronary Artery Disease”Archive Medical Research, 46 (2015) : 112 – 117

 

15-   Maryam Amirchaghmaghi • Zahra Delavarian1 • Mehrdad Iranshahi2 • Mohammad Taghi Shakeri • Pegah Mosannen Mozafari • Amir Hushang Mohammadpour • Fatemeh Farazi • Milad Iranshahy.” A Randomized Placebo-controlled Double Blind Clinical Trial of Quercetin for Treatment of Oral Lichen Planus” .  Journal of Dental Research, Dental Clinics, Dental Prospects(2015) : 9 (1)

 

 

16-Mahmoudi L , Mohammadpour AH , Niknam R , Ahmadi A , Mojtahedzdeh M . Limited sampling strategy for estimation of amikacin optimal sampling time in critically ill adultsAnaesthesia and Intensive Care , 2014; 42(2):228-233Find all citations by this author (default).Or filter your current search Find all citations by this author (default).Or filter your current search

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  17- Mohammad Moshiri, Amir Hooshang Mohammadpour, Maryam Vahabzadeh,

Leila Etemad, Bahram Memar, and Hossein Hosseinzadeh. Evaluating the Effects and Safety of Intravenous Lipid Emulsion on Haloperidol-Induced Neurotoxicity in Rabbit.2014; 108 : 44-47

 

21-.Milad Iranshahi, Amir Hooshang Mohammadpoor, Mohammad Hassanzadeh Khayyat, Mehrdad Iranshahi. Method validation for the one month stability study of trans resveraterol in human plasma. Jundishapour J Nat Pharm Prod, 2013; 8(2); 65-9

 

22-.Maryam Ghorbani , Amir Hooshang Mohamadpour , Soghra Mehri ,Khalil Abnous , Mohammad Hassanzadeh-Khayyat.  Proteomics screening of molecular targets of granulocyte colony stimulating factor in the mouse brain and PC12 cell line. Life Sciences. 2014 In Press

 

23-. Leila Etemad , Afshar Mohammad , Amir Hooshang Mohammadpour , Nasser Vahdati Mashhadi , Seyed Adel Moallem . Teratogenic Effects of Pregabalin in Mice. Iran J Basic Med Sci. 2013; 16: 1065-1070

 

24-.Mohammadpour AH, Akhlaghi F. Future of Cholesteryl Ester Transfer Protein (CETP) Inhibitors: A Pharmacological Perspective. Clin Pharmacokinet. 2013 52(8):615-626

25-Moshiri M1, Vahabzadeh M, Mohammadpour AH, Hosseinzadeh H.  Evaluation of intravenous lipid emulsion on haloperidol-induced hypotension in rabbits. Toxicol Ind Health. 2014 Jan 20. [Epub ahead of print]

26-Mohammadpour AH, Nazemian F1, Khaiat MH, Tafaghodi M, Salari P, Charkazi S, Naghibi M, Shamsara J.  Evaluation of the effect of pentoxifylline on erythropoietin-resistant anemia in hemodialysis patients. Saudi J Kidney Dis Transpl. 2014 Jan;25(1):73-8.

27-.Maryam Vahabzadeh, Mohammad Moshiri,  Amir Hooshang Mohammadpour, and Hossein Hosseinzadeh,  Promising Effects of Intravenous Lipid Emulsion as an Antidote in Acute Tramadol Poisoning. Regional Anesthesia and Pain Medicine, 2013; 38(5): 425-30

28-Amir Hooshang Mohammadpour, Homa Falsoleiman, Jamal Shamsara, Ghazaleh Allah Abadi, Ramin Rasooli ,Mohammad Ramezani .Pentoxifylline Decreases Serum Level of Adhesion Molecules in Atherosclerosis Patients. Iranian Biomedical Journal. Iran Biomed J. Jan 2014; 18(1): 23–27

29-.Amir Hooshang Mohammadpour, Fatemeh Nazemian, Jamal Shamsara, Maryam Bafandegan, Maryam Ghorbani1 and Seyed Adel Moallem . Effects of omega-3 administration on concentration of serum inflammatory makers in renal transplant recipient .African Journal of  Pharmacy and Pharmacology.  2013; 7 (29): 2021-2024

30-. Amir Hooshang Mohammadpour, Mohammad Ramezani, Nasim Tavakoli Anaraki, Bizhan Malaekeh-Nikouei, Sara Amel Farzad, and Hossein Hosseinzadeh.Development and Validation of HPLC Method for Determination of Crocetin, a constituent of Saffron, in Human Serum Samples. Iran J Basic Med Sci. 2013 January; 16(1): 47–55

31-.Maryam M Ghorbani, Seyyed Adel S Moallem, Khalil K Abnous, Seyyed Abbas SA Tabatabaee Yazdi, Ahmad Reza AR Movassaghi, Mohammad M Azizzadeh, Amir Hooshang AH Mohamadpour* Drug Chem Toxicol 36(1):102-8 (2013), The effect of granulocyte colony-stimulating factor administration on carbon monoxide neurotoxicity in rats. Drug Chem Toxicol.2013; 36(1):102-8

32-.Mahmoudi L, Mohammadpour AH, Ahmadi A, Niknam R, Mojtahedzadeh M. Influence of sepsis on higher daily dose of amikacin pharmacokinetics in critically ill patients Eur Rev Med Pharmacol Sci. 2013 Feb;17(3):285-91.

33-AH Mohamadpour, Z Ayati, MR Parizadeh, O Rajbai, H Hosseinzadeh . Safety Evaluation of Crocin (a constituent of saffron) Tablets in Healthy Volunteers
Iranian journal of basic medical sciences. 2013; 16 (1), 39-46

34-.G Kamalinia, S Brand, P Ghaeli, N Abedi, H Bajoghli, V Sharifi, A Zahiroddin , AH Mohammadpour . Serum Levels of Sodium Valproate in Patients Suffering from Bipolar Disorders: Comparing Acute and Maintenance Phases of Mania
Pharmacopsychiatry. 2013;46(3):83-7

35-AH Mohammadpour, SA Moallem, M Bafandegan, J Shamsara, F Nazemian. Effects of omega-3 administration on homocysteine serum concentration in renal transplant recipient ,Journal of Pharmaceutical Care .2013;1 (1), 25-28

36-25.M Hassanzadeh Bashtian, SA Emami, N Mousavifar, HA Esmaily, M Mahmoudi, AH Mohammadpour Evaluation of Fenugreek Effects (Trigonella foenum-graceum L.) Seeds Extract on Insulin Resistance in Women with Polycystic Ovarian Syndrome . Iranian Journal of Pharmaceutical Research. 2013;12(2):475-481

37-Vahid Jomezadeh, Amir Hooshang Mohammadpour,Omid Rajabi, Alireza Tavassoli, Ghodratolah MaddahEvaluation of Curcumin Effects on Post-Operative Peritoneal Adhesion in Rats. Iran J Basic Med Sci. 2012 Nov-Dec; 15(6): 1162–1167.

38-Shabnam Shahsavand, Amir Hooshang Mohammadpour, Ramin Rezaee, Effat Behravan, Ramin Sakhtianchi,and Seyed Adel Moallem. Effect of Erythropoietin on Serum Brain-derived Biomarkers after Carbon Monoxide Poisoning in Rats. Iran J Basic Med Sci. 2012 Mar-Apr; 15(2): 752–758.

39-Shamsara J,Mohammadpour AH, Behravan J,Falsoleiman H,Ramezani M.”Pentoxifylline decreases soluble CD40 ligand concentration and CD40 gene expression in coronary artery disease patients”Immunopharmacol Immunotoxicol. 2012;34(3)523-9

40-Elyasi S,Khalili H,Dashti-Khavidaki S,Mohammadpour A.”Vancomycin-induced nephrotoxicity:mechanism,incidence,risk factors and special populations.A literature review”.Eur J Clin Pharmacol. 2012 Sep;68(9):1243-55

41-Amir Hooshang Mohammadpour,Jamal Shamsara,Saeed Nazemi,Samira Ghadirzadeh,Shabnam Shahsavand and Mohammad Ramezani.”Evaluation of RANKL/OPG serum concentration ratio as a new biomarker for coronary artery calcification:a pilot study.” Thrombosis. 2012; Epub 2012 Mar 28

42-Mohammad Reza Khakzad,Majid Mirsadraee,Amirhooshang Mohammadpour,Kamran Ghafarzadegan,Raziye Hadi,Mahdiye Saghari,Mojtaba Meshkat.”Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals” Pulmonary Pharmacology & Therapeutics.(2012);25:163-168.

43-Amir Hooshang Mohammadpour,Saeed Nazemi,Maryam Foroughi,Maryam Ghorbani,Jamal Shamsara and Javad Behravan.” Evaluation of the association between AT 1 R1166C polymorphism and the incidence of CAD and CAC score in Iranian population ”.Arch.Biol.Sci,Belgrade,2012;64(2),401-407

44-Jamal Shamsara, Javad Behravan, Homa Falsoleiman, Amir Houshang Mohammadpour, Mohammad Ramezani. The effects of pentoxifylline administration on NFΚB P50 transcription factor expression. ARYA A therosclorosis. 2012;7 (4):133-137

45-.Aghebati T, Foroughipour M, Azarpazhooh MR, Mokhber N, Hasanzadeh Khayat M, Vahdati N, Mohammadpour AH*. Relationship between Patient Demographic Characteristics, Valproic Acid Dosage and Clearance in Adult Iranian Patients. Iran J Basic Med Sci. 2012 Mar;15(2):702-8

46-.Mitra Asgharian Rezaeea, Seyed Adel Moallem, Mohsen Imenshahidi, Mahdi Farzadniac and Amir Hooshang Mohammadpour*Effects of Erythropoietin on Electrocardiogram Changes in Carbon Monoxide Poisoning: an Experimental Study in Rats.  Iranian Journal of Pharmaceutical Research .2012; 11 (4): 1191-1199

47-S Lotfi Noghabi, A Vahidian Kamyad, M Foroughipour, AH Mohammadpour Estimating the Optimal Dosage of Sodium Valproate in Idiopathic Generalized Epilepsy with Adaptive Neuro-Fuzzy Inference System. Basic and Clinical Neuroscience .2012;3 (3): 24-31

48-Jamal Shamsara,Javad Behravan,Homa Falsoleiman,Amir Hooshang Mohammadpour,Joerg Renderis,Mohammad Ramezani.Pentoxifylline administration changes protein expression profile of coronary artery disease patients. 2011 Nov 1;487(1):107-11

49-Amir Hooshang Mohammadpour, Fatemeh Nazemian, Reza K, Reza Kouhrokhi,Mohammad Ramezani , Jamal Shamsara “Effect Of Omega-3 Fatty Acids On Plasma Level Of 8-Isoprostane In Kidney Transplant Patients” Journal of Renal Nutrition , 2011; 21(2): 196-199

 

50-Amir Hooshang Mohammadpour,Fatemeh Nazemian,Seyed Adel Moallem,Seyed Ali Alamdaran,Elham Asad-Abadi,Jamal Shamsara. Correlation between Heat-Shock Protein 27 serum concentration and common carotid intima-media thickness in hemodialysis patients.Iranian Journal of Kidney Diseases.2011; 5:260-6 2011.

51-Mohamadpour AH, Moallem SA, Hashemzaei M, Abnous K, Tabatabaee Yazdi SA, Imenshahidi M.” Effects of granulocyte colony-stimulating factor on electrocardiogram changes after carbon monoxide poisoning in rats” Drug Chem Toxicol. 2012 ; 35(4),353-360.

52-Amir Hooshang Mohammadpour,Mohsen Foroughipour, Mahmoud Reza Azarpazhooh, Mohammad Hasanzadeh Khayat,Saeed Rezaee,Tamara Aghebati,Jamal Shamsara. Comparison of valporic acid clearance between epileptic patients and patients with acute mania.Iranian journal of basic medical sciences. 2011;14(6): 546-550

53-.Niloufar Mohammadpour, Sepideh Elyasi,Naser vahdati,Amir Hooshang Mohammadpour*,Jamal Shamsara.A review on therapeutic drug monitoring of Immunosuppressant drugs. Iranian journal of basic medical sciences, 2011; 14(6), 485-498

54-Seyed adel Moallem, Fatemeh Nazemian , Sepideh Eliasi ,Seyed Ali Alamdaran, Jamal Shamsara, Amir Hooshang Mohammadpour* “Correlation between CathepsinD serum concentration and carotid intima media thickness in hemodialysis patients” Int Urol Nephrol 2011 Sep;43(3):841-8

55-.Mehdi Bakhshaee, Farahzad Jabbari, Saeed Hoseini, Reza Farid, Mohammad Hadi Sadeghian, Mohsen Rajati, Amir Houshang Mohamadpoor, Rahman Movahhed, and Mohammad Ali Zamani. Effect of Silymarin in the Treatment of Allergic Rhinitis. Otolaryngology–Head and Neck Surgery. 2011;145(6) :904–909

56-N.Moosavifar,AH Mohammadpour,M Jallali,G karimi and H saberi.Evaluation of effect of silymarin on granulose cell apoptosis and follicular development in patients undergoing in vitro fertilization.Eastern meditererranean Health Journal.2010; 16(6):642-45.

57- Afshar M, Moallem SA, Houshang Mohammadpour A, Shiravi A, Majid Jalalian S, Jafar Golalipour M.” Teratogenic effects of carbamazepine on embryonic eye development in pregnant mice” Cutan Ocul Toxicol. 2010 Mar;29(1):10-15

58-Amir Hooshang Mohammadpour, Fatemeh Nazemian, Gholamreza Karimi, Mahdi Moatamedi, Somayeh Charkazi, Jamal Shamsara . “ Effect of Silymarin Administration on TNF-α serum concentration in peritoneal dialysis” Phytotherapy Research, 2010; 24: 1654-1657

59-Foroughipour M, Mohammadpour AH*, Azarpajooh MR, Mokhber N, Hasanzadeh Khaiat M, Rezaee S, Aghebati T, Vahdati N, Shamsara J “Therapeutic Drug Monitoring of valproic acid in patients with monotherapy at steady state”: Iranian Journal of Basic Medical science. 2009;12(3):146-149

 

60-Bazzaz BS, Naderinasab M, Mohamadpoor AH, Farshadzadeh Z, Ahmadi S, Yousefi F. The prevalence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae among clinical isolates from a general hospital in Iran. Acta Microbiol Immunol Hung. 2009 Mar;56(1):89-99.

 

61-.J Shamsara, M Ramezani, AH Mohammadpoor*Why homocysteine-lowering therapy does not have beneficial effects on patients with cardiovascular disease?
Bioscience Hypotheses .2009 ;2 (1):13-15

62-Amir Hooshang Mohammadpur, Fatemeh Nazemian, Bahareh Abtahi, Massih Naghibi “Influence of renal graft function on mycophenolic acid pharmacokinetics during the period after kidney transplant”. Experimental and Clinical Transplantation. 2008; 4:276-281

63-Mohammadpour AH, Nazemian F, Abtahi B, Naghibi M, Rezaee S, Rajzbi O “ Estimation of abbreviated Mycophenolic acid area under the concentration time curve during post transplant period by limited sampling strategy” Transplantation Proceeding . 2008,;40:3668-3672 

64-Mohammad Pour AH, Nazemian F, Hassanzadeh Khayat M, Bahrami A.A., Kazemi M. “Effect of Gancyclovir on Pharmacokinetics of Mycophenolate Mofetil in Kidney Transplant Patients” Iranian Journal of Basic Medical Sciences. 2008; 10 (4): 233-238

65-Nazemian F, Mohammadpur AH*, Abtahi B, Naghibi M “Pharmacokinetics of mycophenolic acid during the early period after renal transplant: Exprimental and clinical transplantation. 2007; 5 (2): 658-63

66-M Abbasi Nazari, AH Mohammadpour, J Behjati ardakani, , MR Rouini, KH Gholami The effect  of atenolol on thyroid hormons  in subclinical  hyperthyroidism , Iranian Journal of Pharmaceutical Sciences. 2005;1(4): 243-248

67-Mohammadpoor AH, sadraee S, Ghaeli P, foroughipoor M, Noroozian M, Rezaee S. Comparison of carbamazepin clearance between epileptic patients and paitents with acute Mania, DARU, 2004; 12 (4): 141-144

 

                                                                      Presentations

 

 

 

 

 

 

 

 

 

 

                                                                    Honors & Awards

 

2011  Outstanding Scientist Award, Mashhad University of Medical Sciences

 

2016 Outstanding Educational Award, Mashhad University of Medical Sciences

 

 

 

Membership

 

Rational Use of Drugs Council, Mashhad University of Medical Sciences, Mashhad, Iran

 

Ethic committee  Research Council, Mashhad University of Medical Sciences, Mashhad, Iran

 

 

                                                           Administrative Responsibilities

 

2006-2012 Chair of Department of Pharmacodinamy and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

 

2009-2011 , vice chancellor for research, School of Pharmacy, Mashhad University of Medical

Sciences, Mashhad, Iran

 

2013 -2016 Chair of Department of Clinical Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

 

 

 

 

Other Skills