Pharmaceutical Research Center

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ü Professors and key members

ü Strategic Plan

 

Perspective

Our ultimate goal is to be recognized as a national academic and research hub in pharmaceutical sciences through executing various basic and practical researches in the field of pharmaceutical sciences.

 

Mission

  1. Basic researches in the field of pharmaceutical sciences in order to promote and develop science
  2. Practical researches relative to pharmaceutical sciences in the fields of industry, health, and treatment.
  3. Providing an appropriate environment with necessary equipment and laboratory facilities and inspired and motivated researches in order to perform different researches.
  4. Strong communication with other science centers and attraction of credits from outside the organization.

 

Overall goals

G1. Development and promotion of science through increasing the number of authentic national and international articles.

G2. Performing different practical researches deemed necessary by the society in the fields of treatment, health, and related industries.

G3. Promoting the centers ranking amongst other national science centers.

 

 

ü  Equipment and Facilities

 

Department of Nanomedicine

Supervisor: Dr. Mohammadreza Ramazani (Professor of Medicinal Biotechnology)

Equipment include: MPLC, refrigerated centrifuge, optical microscope, UV cabinet, vacuum centrifuge, ELISA reader, freeze dryer, all equipment required for column chromatography and TLC, sonicator, solvent removal device, and soxhlet device. Four computers with high-speed internet along with scanner and printer.

 

Department of Analysis

Supervisor: Dr. Mohammad Hassanzadeh Khayat (Professor of Medicinal Chemistry)

Equipment include: UV-VIS spectrophotometer, infra-red spectrophotometer, spectrofluorimeter device, high performance liquid chromatography device (HPLC) for analysis of different substances (qualitatively and quantitatively). 2 computers with internet access.

 

Department of Pharmacodynamics

Supervisor: Dr. Hossein Hosseinzadeh (Professor of Pharmacology)

Equipment include: HPLC device, Power Lab device, solvent removal device, hot plate, water maze (MWM), dry heater, oven, microscope with computer connective camera, centrifuge, digital scale, stereotaxy, etc.  Four computers with high-speed internet and one printer.

 

Department of Toxicology and Teratology

Supervisor: Dr. Seyed Adel Moalem (Professor of Toxicology)

Equipment include: tom mice fetus and organ culture device, several stereomicroscopes and digital imaging system for investigating fetal abnormalities, microtome, laminar hood, CO2 incubator and invert microscopes for cell culture, ELISA device, spectrophotometer, PCR gradient device, gel sequencing device, electrophoresis device for studying DNA, RNA, and proteins, and liquid nitrogen tanks for long-term preservation of cells. Two computers with high-speed internet along with two printers.

 

 

 

ü  Research Activities

  • Theses

 

Dr. Imen Shahidi

Effects of Dexrazoxane on aluminum posphide cardiotoxicity in rats

Effects of curcumin on prevention of under chronic cardiovascular damages resulting from Bisphenol A in rats

Protective effects of alcohol extract of lemon verbena leaves and verbascoside effective material on indomethacin-induced peptic ulcer in rat

Protective effect of lemon verbena leaf aqueous extract on indomethacin-induced peptic ulcer in rat

Effects of acute Montmorillonite in acute lithium carbonate–induced toxicity in rat

Dr. Ramazani

DNA aptamer isolation for specific identification of PD-L1(CD274) and performance review

Targeted delivery of irinotecan via Aptamer-PEG-acetylated carboxymethyl cellulose complex to colorectal cancer cells

Electrospun nanofibers containing BMP-2 liposomal peptide to increase mesenchymal stem cell differentiation to bone

PLGA-based nanoparticles loaded with doxorubicin and targeted using PNC-27 peptide as a targeted anti-cancer system

Evaluation of targeted pharmaceuticals to breast cancer cells resistant to MCF/7MX drug using ABCG2 specific aptamer transporter

Effects of crocin and crocetin substances extracted from saffron on mesenchymal cell differentiation in bone cells

Effects of saffron-extracted crocetin and PLGA nanoparticles containing crocetin on incidence of multi-drug resistance phenotype

Procurement of antigen-containing exosomal nanocarriers for tumor treatment

Dr. Abnoos

DNA aptamer isolation for specific identification of PD-L1(CD274) and performance review

Carbon paste electrode-based electrochemical sensors modified using polymer molecule framework nanoparticles for determining Diazinon dosage

Targeted delivery of irinotecan via Aptamer-PEG-acetylated carboxymethyl cellulose complex to colorectal cancer cells

Evaluation of targeted pharmaceuticals to breast cancer cells resistant to MCF/7MX drug using ABCG2 specific aptamer transporter

PLGA-based nanoparticles loaded with doxorubicin and targeted using PNC-27 peptide as a targeted anti-cancer system

Procurement of antigen-containing exosomal nanocarriers for tumor treatment

Dr. Mehri

Effects of tropisetron on oxazaphosphorine-induced hemorrhagic cystic (cyclophosphamide or ifosfamide) in rat

Dr. Hosseinzadeh

Mechanism review of protective effects of crocin on cell toxicity resulting from oxidative stress in isolated hepatocytes in rat

Effects of crocin on human lymphocyte proliferation and Thelper1 and Thelper2 balance

Protective effects of Q10 co-enzyme on acrylamide-induced neurotoxicity in in vivo and in vitro models

Effects of safranal on metabolic disorders resulting from olanzapine consumption in rat

Anti-depressant effects of grape seed extract and resveratrol on postpartum forced swimming and depression model in mice

Effects of crocin on inducing phenotype switching of macrophages to anti-inflammatory M2 state

Effects of thymoquinone on D-galactose induced aging model in rat: memory disorders and its mechanisms

Effects of crocin on nerve damage induced by D-galactose induced aging model in cellular (SH-SS5Y) and animal (rat) environment

Anti-depressant effect of aqueous and ethanol extracts of lemon verbena leaves and its primary substance, verbascoside, on postpartum forced swimming and depression model in mice

Dr. Leila Etemad

Effects of cinnamic aldehyde on methamphetamine-induced nerve damage in PC12 cell

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

in vivo evaluation of aromatase enzyme inhibition using a new composition of 4-(1-imidazole-1-Il)methyl-2-4-methoxy-phenyl benzo quinoline in rat

Anticonvulsant effects of Suvorexant in mice

Effects of acute Montmorillonite on acute lithium carbonate-induced toxicity in rat

Effects of curcumin nanomicelles on phosphine-induced cell damage in HepG2 cell

Effects of pregabalin on nerve evolution using mouse embryonic stem cells

Dr. Seyed Adel Moalem

Effects of cinnamic aldehyde on methamphetamine-induced cell damage in PC12 cell

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

Effects of acute Montmorillonite on acute lithium carbonate-induced toxicity in rat

Effects of pregabalin on nerve evolution using mouse embryonic stem cells

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with potential biomarkers effecting atherosclerosis in patients suffering from chronic cardiac ischemia

Dr. Roohbakhsh

Effects of flavonoid dihydromirestin on expression and acquisition of CPP and symptoms of morphine-induced addiction in mice

Dr. Saeed Islami

 

Anti-depressant effects of saffron stigma in pregnant women suffering from postpartum depression

Anti-depressant effects of saffron stigma tablets on pregnant women suffering from non-major postpartum depression

Study on the relationship between NSAIDS consumption and gastrointestinal bleeding in patients with upper gastrointestinal bleeding referring to Qaem Hospital during 2014

Rational prescription of clozapine and prevalence of agranulocytosis in a sample from Ibn Sina Psychiatry Hospital of Mashhad.

Investigation of doctors prescribing behavior pregnant mothers regarding insurance prescriptions in Razavi Khorasan Province in order to assess inappropriate prescriptions of drugs during pregnancy and establish localized drug prescription instructions for pregnancy consistent with national status.

Relationship between anxiety and educational performance in Mashhad Pharmacy School students

Dr. Mohammad Hasanzadeh Khayat

Carbon paste electrode-based electrochemical sensors modified using polymer molecule framework nanoparticles for determining Diazinon dosage

 

Evaluation of serum concentrations of neopterin as an individual cardiovascular biomarker in patients suffering from coronary artery diseases

Amount of ethanol and methanol in alcohol-free beer brands in Iranian markets

Dr. Afrasiabi

Effects of different types and concentrations of plasticizers on characteristics of microcapsules from three different ethyl cellulose viscosities containing sodium diclophenac procured using emulsion-evaporation of solvent method

Procurement and evaluation of slow-release metoprolol microcapsules using eudragit RS polymers and ethyl cellulose

Performance review of Carr’s Index and Hausner Ratio for determining characteristics of powder flows and evaluating the effects of factors such as powder particle size and type and amount of glidant on these indicators

Comparison of the effects of nerolidol and oleic acid as an enhancer for skin permeability of diclophenac D –ethyl amine in patches provided using R-L eudragit base

Dr. Amir Hooshang Mohamadpoor

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

Evaluation of serum concentrations of neopterin as an individual cardiovascular biomarker in patients suffering from coronary artery diseases

Effects of topical creams containing honey and aloe vera in treatment of radiotherapy-induced dermatitis in breast cancer patients

Dr. Seyed Ahmad Mohajeri

Evaluation of vitamin A suppositories for vaginal use

Protective effects of crocin and corcetin against hyperglycemic damage in retina cells

Procurement of fluorometholone molecular molded hydrogels as ocular drug delivery systems and investigation of binding properties of the drug and its release into the environment

 

 

 

 

  • Articles
    • 2011 publications
  1. Interaction of methylxanthines and gentamicin against Staphylococcus aureus and Pseudomonas aeruginosa: Role of phosphodiesterase inhibition
  2. Euphorbia Microsciadia Percolatio A D Soxhlet Extracts Exhibit A Tiviral Activity
  3. Effects of Aqueous and Ethanolic Leaf Extracts of Mentha Longifolia on Morphine Dependence in Mice
  4. Effects of Crocin on the Acquisition and Reinstatement of Morphine-induced Conditioned Place Preference in Mice
  5. Inhibitory Effect Of Aqueous Extract Of Saffro (Crocus Sativus L.) O Adjuva T-I Duced Arthritis I Wistar Rat
  6. Neuroprotective Effect of Crocin on Acrylamide-induced Cytotoxicity in PC12 cells
  7. Phototoxicity activity of Psoralea drupacea L. using Atremia salina bioassay system
  8. Preparation, Characterization and Evaluation of Sun Protective and Moisturizing Effects of Nanoliposomes Containing Safranal
  9. Study Of A Titumor Effect Of Metha Olic A D Aqueous Extracts Of Allium Stivum L. (Garlic) Cloves Usi G Potato Disc Bioassay
  10. The effect of crocin and safranal, constituents of saffron, against subacute effect of diazinon on hematological and genotoxicity indices in rats
  11. Alginate microspheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN induced partial protection and enhanced immune response against murine model of leishmaniasis
  12. A Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs
  13. Antioxidant activity of the essential oils of different parts of Juniperus excelsa M. Bieb. subsp. excelsa and J. excelsa M. Bieb. subsp. polycarpos (K. Koch) Takhtajan (Cupressaceae)
  14. Correlation between cathepsin D serum concentration and carotid intima-media thickness in hemodialysis patients.
  15. Comparison of physicomechanical properties of films prepared from organic solutions and aqueous dispersion of Eudragit RL
  16. Correlation between heat-shock protein 27 serum concentration and common carotid intima-media thickness in hemodialysis patients
  17. Effect of Zataria multiflora Bois L. on histamine (H1) receptor of guinea pig tracheal chains.
  18. Effects of Saffron (Crocus sativus L.) and its Active Constituent, Crocin, on Recognition and Spatial Memory after Chronic Cerebral Hypoperfusion in Rats
  19. Glutamate racemization and catabolism in Fusobacterium varium
  20. Immunization against leishmaniasis by PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN
  21. Pentoxifylline administration changes protein expression profile of coronary artery disease patients
  22. Prevalence of Exercise Induced Asthma in Female School Students
  23. Pharmacological Effects of Rosa Damascena
  24. Production of Ibuprofen Pellets Containing High Amount of Rate Retarding Eudragit RL Using PEG400 and Investigation of Their Physicomechanical Properties
  25. Pulmonary function tests and respiratory symptoms among smokers in the city of mashhad (north east of Iran)
  26. Quantitative LC Analysis of Cyclosporine A in Ocular Samples
  27. Synthesis of Novel 4-[1-(4-fluorobenzyl)-5-imidazolyl] Dihydropyridines and Studying their Effects on Rat Blood Pressure
  28. The effect of Nigella sativa alone, and in combination with dexamethasone, on tracheal muscle responsiveness and lung inflammation in sulfur mustard exposed guinea pigs
  29. The effect of Crocus sativus extract on human lymphocytes' cytokines and T helper 2/T helper 1 balance.
  30. The effect of carvacrol on muscarinic receptors of guinea-pig tracheal chains.
  31. The effect of Nigella sativa extract on tracheal responsiveness and lung inflammation in ovalbumin-sensitized guinea pigs.
  32. Antioxidant effects of the essential oils of different parts of platycladus orientalis L. (Franco) and their components
  33. Comparison of Valproic acid Clearance between Epileptic Patients and Patients with Acute Mania
  34. Clozapine Recognition via Molecularly Imprinted Polymers; Bulk Polymerization Versus Precipitation Method
  35. Preventive Effect of Vitamin B6 on Developmental Toxicity of Carbamazepine in Mice
  36. Teratogenic effects of HESA-A, a natural anticancer product from Iran, in mice
  37. Zataria multiflora Boiss and Carvacrol Affect beta(2)-Adrenoceptors of Guinea Pig Trachea
  38. Effect of Aqueous-Ethanolic Extract from Rosa damascena on Guinea Pig Isolated Heart
  39. Antioxidant and antimicrobial activity of methanol, dichloromethane, and ethyl acetate extracts of Scutellaria litwinowii
  40. Comparison of Chemical Composition of Achillea eriophora and A. wilhelmsii Grown in Wild and Cultivated Conditions in Iran
  41. Expression of Drug Pump Protein MRP2 in Lipopolysaccharide-Treated Rats and its Impact on the Disposition of Acetaminophen
  42. Identification of Spathulenol in Salvia mirzayanii and the Immunomodulatory Effects
  43. Improvement of cytotoxic and apoptogenic properties of crocin in cancer cell lines by its nanoliposomal form
  44. Liposome-linear polyethyleneimine- DNA Nanocomplexes for Gene Delivery: Preparation, Characterization and In Vitro Transfection Activity
  45. Effect of the two new calcium channel blockers mebudipine and dibudipine on vascular flow of isolated kidney of normal and diabetic rats
  46. Immunoinhibitory effect of teuclatriol a guaiane sesquiterpene from Salvia mirzayanii
  47. Antiviral and antimicrobial activity of Thymus transcaspicus essential oil
  48. New N-aryl-4-(methysulfony)aminobenzenesulfonamid es as selective COX-2 inhibitors
  49. Quantitative LC analysis of Methotrexate and its application in pharmacokinetic study of drug in rat serum samples
  50. Serum vitamin E concentration in Iranian population with angiography defined coronary artery disease
  51. Possible mechanism(s) of the relaxant effect of asafoetida (Ferula assa-foetida) oleo-gum-resin extract on guinea-pig tracheal smooth muscle
  52. Evaluation of nitric oxide or opioid receptors involvement in antinociceptive properties of silymarin
  53. Evaluation of RANKL/OPG Serum Concentration Ratio as a New Biomarker for Coronary Artery Calcification: A Pilot Study
  54. Degradation of Diclofenac in Molecularly Imprinted Polymer Submicron Particles by UV Light Irradiation and HCl Acid Treatment
  55. Effects of sage (Ocimun bacilicum) extract fractions on morphine withdrawal syndrome in mice

 

  • 2012 publications
  1. Virtual screening for finding novel COX-2 inhibitors as antitumor agents
  2. Effect of Erythropoietin on Serum Brain-derived Biomarkers after Carbon Monoxide Poisoning in Rats
  3. Effects of erythropoietin on electrocardiogram changes in carbon monoxide poisoning: An experimental study in rats
  4. Synthesis and Immunomodulation of Human Lymphocyte Proliferation and Cytokine (Interferon-gamma) Production of Four Novel Leflunomide Analogues
  5. Anti-nociceptive and Anti-inflammatory Effects of Cyanocobalamin (Vitamin B12) Against Acute and Chronic Pain and Inflammation in Mice
  6. Epilepsy drugs and effects on fetal development: Potential mechanisms
  7. The effect of granulocyte colony-stimulating factor administration on carbon monoxide neurotoxicity in rats
  8. Anti-cholinergic effect of Zataria multiflora Boiss on guinea pig tracheal chains
  9. The effect of vitamin E on pathological changes in kidney and liver of sulphur mustard-exposed guinea pigs
  10. The effect of the extract of Crocus sativus and its constituent safranal, on lung pathology and lung inflammation of ovalbumin sensitized guinea-pigs
  11. Inhibitory effect of Zataria multiflora Boiss and carvacrol on histamine (H1) receptors of guinea-pig tracheal chains
  12. Exercise induced bronchospasm in physically fit female students of Kerman University and their pulmonary function tests
  13. Relationship between Patient Demographic Characteristics, Valproic Acid Dosage and Clearance in Adult Iranian Patients
  14. Sonodynamic Therapy Using Protoporphyrin IX Conjugated to Gold Nanoparticles: An In Vivo Study on a Colon Tumor Model
  15. Determination of heavy metals in different honey brands from Iranian markets
  16. Nicotine Content of Domestic Cigarettes, Imported Cigarettes and Pipe Tobacco in Iran
  17. Acute and Subacute Toxicity of Safranal, a Constituent of Saffron, in Mice and Rats
  18. Effect of Linalool on Morphine Tolerance and Dependence in Mice
  19. Safranal: From an Aromatic Natural Product to a Rewarding Pharmacological Agent
  20. Safety Evaluation of Crocin (a constituent of saffron) Tablets in Healthy Volunteers
  21. Antioxidant Activity of Pistacia vera Fruits, Leaves and Gum Extracts
  22. Cardioprotective Effect of Saffron Extract and Safranal in Isoproterenol-Induced Myocardial Infarction in Wistar Rats
  23. Crocin Restores Hypotensive Effect of Subchronic Administration of Diazinon in Rats
  24. Development and Validation of HPLC Method for Determination of Crocetin, a constituent of Saffron, in Human Serum Samples
  25. Antinociceptive Evaluation Of Ceftriaxone And Minocycline Alone And In Combination In A Neuropathic Pain Model In Rat
  26. Effect of thymoquinone, a constituent of Nigella sativa L., on ischemia-reperfusion in rat skeletal muscle
  27. Effect of aqueous extract of Crocus sativus L. (saffron) stigma against subacute effect of diazinon on specific biomarkers in rats.
  28. In vitro insulin release from thermosensitive chitosan hydrogel
  29. Affinity-based target deconvolution of safranal
  30. Protective Effect of Silymarin against Acrolein-Induced Cardiotoxicity in Mice
  31. Suppression of MAPKAPK2 during mammalian hibernation
  32. Effects of granulocyte colony-stimulating factor on electrocardiogram changes after carbon monoxide poisoning in rats
  33. Development of a novel histone H1-based recombinant fusion peptide for targeted non-viral gene delivery
  34. Umbelliprenin is cytotoxic against QU-DB large cell lung cancer cell line but anti-proliferative against A549 adenocarcinoma cells
  35. The Effect of Lipopolymer Structure on the Transfection Efficiency of Hydrophobic Polyethylenimine-based Cationic Nanoliposomes
  36. beta-Galactosylated Alkyl-oligoamine Derivatives of Polyethylenimine Enhanced pDNA Delivery into Hepatic Cells with Reduced Toxicity
  37. Pentoxifylline decreases soluble CD40 ligand concentration and CD40 gene expression in coronary artery disease patients
  38. Evaluation of Curcumin Effects on Post-Operative Peritoneal Adhesion in Rats
  39. Determination of parathion, aldicarb, and thiobencarb in tap water and bottled mineral water in Mashhad, Iran
  40. In vitro Leishmanicidal activity of Calotropis gigantea and its fractions against Leishmania major
  41. Application of molecularly imprinted hydrogel for the preparation of lactose-free milk
  42. Preparation and Investigation of Sustained Drug Delivery Systems Using an Injectable, Thermosensitive, In Situ Forming Hydrogel Composed of PLGA-PEG-PLGA
  43. Development of a pH-responsive imprinted polymer for diclofenac and study of its binding properties in organic and aqueous media
  44. The potential effect of the extract of Crocus sativus and safranal on the total and differential white blood cells of ovalbumin-sensitized guinea pigs
  45. Tracheal responsiveness to methacholine and ovalbumin; and lung inflammation in guinea pigs exposed to inhaled lead after sensitization
  46. Respiratory symptoms and pulmonary function testes in lead exposed workers
  47. Evaluation of aqueous and ethanolic extracts of saffron, Crocus sativus L., and its constituents, safranal and crocin in allodynia and hyperalgesia induced by chronic constriction injury model of neuropathic pain in rats
  48. Anxiolytic and Hypnotic Effects of Aqueous and Ethanolic Extracts of Aerial Parts of Echium italicum L. in Mice
  49. Review Of Pharmacological And Toxicological Effects Of Nigella Sativa And Its Active Constituents
  50. Can We Accurately Assess Liver Fibrosis with Fibroscan (R) Using Fewer Valid Measurements?
  51. Prediction of Poor Outcome in Patients with Acute Liver Failure-Systematic Review of Prediction Models
  52. Effect of verapamil on bronchial goblet cells of asthma: An experimental study on sensitized animals
  53. Antiemetic activity of volatile oil from Mentha spicata and Mentha * piperita in chemotherapy-induced nausea and vomiting.
  54. Mucosal Adjuvant Potential of Quillaja saponins and Cross-linked Dextran Microspheres, Co-administered with Liposomes Encapsulated with Tetanus Toxoid
  55. Anticonvulsant effect of Berberis integerrima L. root extracts in mice
  56. Evaluation of RANKL/OPG Serum Concentration Ratio as a New Biomarker for Coronary Artery Calcification: A Pilot Study
  57. The Effect of Cationic Charge Density Change on Transfection Efficiency of Polyethylenimine
  58. The effects of pentoxifylline administration on NFΚB P50 transcription factor expression
  59. Plasmid DNA delivery into hepatocytes using a multifunctional nanocarrier based on sugar-conjugated polyethylenimine
  60. Preparation and analysis of a sustained drug delivery system by PLGA-PEG-PLGA triblock copolymers
  61. Controlled release of prednisolone acetate from molecularly imprinted hydrogel contact lenses
  62. Influence of sepsis on higher daily dose of amikacin pharmacokinetics in critically ill patients
  63. Evaluation Of The Association Between At(1)R1166c Polymorphism And The Incidence Of Cad And Cac Score In The Iranian Population
  64. Organic solution versus aqueous dispersion of Eudragit RS in preparation of sustained release microparticles of theophylline using spray drying

 

  • 2013 publications
  1. Cannabinoid System of the Lateral Septum in the Modulation of Anxiety-like Behaviors in Rats
  2. Traditional Chinese and Indian medicine in the treatment of opioid-dependence: a review
  3. Effect of the Zataria multiflora on systemic inflammation of experimental animals model of COPD.
  4. Protective effect of crocin on diazinon induced cardiotoxicity in rats in subchronic exposure
  5. Co-prescription of Gastroprotective Agents and Their Efficacy in Elderly Patients Taking Nonsteroidal Anti-inflammatory Drugs: A Systematic Review of Observational Studies
  6. Organic solution versus aqueous dispersion of Eudragit RS in preparation of sustained release microparticles of theophylline using spray drying
  7. Preparation of a Molecularly Imprinted Soft Contact Lens as a New Ocular Drug Delivery System for Dorzolamide
  8. Alkylcarboxylate Polyethylenimine-grafted Chitosans as Efficient Gene Vectors with Improved Gene Delivery Activity
  9. Crocetin Attenuates Spatial Learning Dysfunction and Hippocampal Injury in a Model of Vascular Dementia
  10. Effects of rutin on acrylamide-induced neurotoxicity
  11. Synthesis and molecular modeling of six novel monastrol analogues: evaluation of cytotoxicity and kinesin inhibitory activity against HeLa cell line
  12. Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus
  13. Proteomic screening of molecular targets of crocin
  14. Lead exposure affects inflammatory mediators, total and differential white blood cells in sensitized guinea pigs during and after sensitization
  15. Preparation and characterization and release properties of Eudragit RS based ibuprofen pellets prepared by extrusion spheronization: effect of binder type and concentration
  16. Effect of cyanocobalamin (vitamin B12) in the induction and expression of morphine tolerance and dependence in mice
  17. Antiemetic activity of volatile oil from Mentha spicata and Mentha x piperita in chemotherapy-induced nausea and vomiting
  18. Epirubicin loaded super paramagnetic iron oxide nanoparticle-aptamer bioconjugate for combined colon cancer therapy and imaging in vivo
  19. Preparation and Evaluation of Histamine Imprinted Polymer as a Selective Sorbent in Molecularly Imprinted Solid-Phase Extraction Coupled with High Performance Liquid Chromatography Analysis in Canned Fish
  20. Bioactivity assessment and toxicity of crocin: A comprehensive review
  21. Inter-observer and Intra-observer Agreement in Pathological Evaluation of Non-alcoholic Fatty Liver Disease Suspected Liver Biopsies
  22. Umbelliprenin induced production of IFN-gamma and TNF-alpha, and reduced IL-10, IL-4, Foxp3 and TGF-beta in a mouse model of lung cancer
  23. A study on druggability of MIA as a promising approach for inhibition of metastasis
  24. Arginine-rich hydrophobic polyethylenimine: Potent agent with simple components for nucleic acid delivery
  25. From rationally designed polymeric and peptidic systems to sophisticated gene delivery nano-vectors
  26. Non-covalent functionalization of single-walled carbon nanotubes with modified polyethyleneimines for efficient gene delivery
  27. Pentoxifylline Decreases Serum Level of Adhesion Molecules in Atherosclerosis Patients
  28. Synthesis, Anti-Inflammatory and Anti- Nociceptive Activities and Cytotoxic Effect of Novel Thiazolidin-4-ones Derivatives as Selective Cyclooxygenase (COX-2) Inhibitors
  29. Teratogenic Effects of Pregabalin in Mice
  30. Teratogenic Effects of Long Term Consumption of Potassium Benzoate on Eye Development in Balb/c Fetal Mice
  31. The Effects of Low Level Laser Therapy on the Expression of Collagen Type I Gene and Proliferation of Human Gingival Fibroblasts (Hgf3-Pi 53): in vitro Study
  32. Improvement of Physico-mechanical Properties of Partially Amorphous Acetaminophen Developed from Hydroalcoholic Solution Using Spray Drying Technique
  33. The Effect of Carvacrol on Serum Cytokines and Endothelin Levels of Ovalbumin Sensitized Guinea-Pigs
  34. Inter-individual Variability of Coumarin 7-hydroxylation (CYP2A6 activity) in an Iranian Population
  35. Effects of chronic crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats
  36. Failure of Intravenous Lipid Emulsion to Reduce Diazinon-induced Acute Toxicity: a Pilot Study in Rats
  37. Cytotoxic effects of crocin on MOLT-4 human leukemia cells
  38. Targeted delivery of Epirubicin to cancer cells by PEGylated A10 aptamer.
  39. Dummy Template Molecularly Imprinted Polymer for Omeprazole and the Study of Its Drug Binding and Release Properties
  40. Molecular weight-dependent genetic information transfer with disulfide-linked polyethylenimine-based nonviral vectors
  41. Preparation and characterisation of PLGA-PEG-PLGA nanospheres prepared with a new thermogelling method for insulin delivery
  42. Pyrimido 5,4-e tetrazolo 5,1-b 1,3,4 thiadiazines as a new heterocyclic system
  43. Extraction of Lycopene from Tomato Paste by Ursodeoxycholic Acid Using the Selective Inclusion Complex Method
  44. Targeted gene delivery with noncovalent electrostatic conjugates of sgc-8c aptamer and polyethylenimine
  45. Effect of carbamazepine on homocysteine serum level in pregnant mice and fetal malformations outcome
  46. Antihypertensive Effect of Celery Seed on Rat Blood Pressure in Chronic Administration
  47. Saffron: A Herbal Medicine of Third Millennium
  48. Saffron Reduced Toxic Effects of its Constituent, Safranal, in Acute and Subacute Toxicities in Rats
  49. The Effect of Chronic Administration of Saffron (Crocus sativus) Stigma Aqueous Extract on Systolic Blood Pressure in Rats
  50. Antioxidant Activity of Leaves and Fruits of Cultivated Conifers in Iran
  51. Gene Transfer Enhancement by Alkylcarboxylation of Poly(propylenimine)
  52. Evaluation of cyclosporine A eye penetration after administration of liposomal or conventional forms in animal model
  53. A novel label free cocaine assay based on aptamer-wrapped single-walled carbon nanotubes
  54. Tactile Learning within the Early Phase of Experimental Autoimmune Encephalomyelitis in Mice
  55. Hypotensive Effect of a Novel Dihydropyridine with Dual Calcium Channel Blocking and Angiotensin II Antagonistic Properties in a Rat Model
  56. Frequency and nature of drug-drug interactions in the intensive care unit
  57. The effect of intra-ventral hippocampus administration of TRPV1 agonist and antagonist on spatial learning and memory in male rats
  58. Serum Levels of Sodium Valproate in Patients Suffering from Bipolar Disorders: Comparing Acute and Maintenance Phases of Mania
  59. Assessment of Cytotoxic Properties of Safranal and Nanoliposomal Safranal in Various Cancer Cell Lines
  60. Avicenna's (Ibn Sina) the Canon of Medicine and Saffron (Crocus sativus): A Review
  61. Antitumor Activity of PEGylated Nanoliposomes Containing Crocin in Mice Bearing C26 Colon Carcinoma
  62. Promising effects of intravenous lipid emulsion as an antidote in acute tramadol poisoning
  63. Blood Bag emperature Monitoring System
  64. Web-site evaluation tools: a case study in reproductive health information.
  65. Attitudes and Experience of Dutch General Practitioners Regarding Computerized Clinical Decision Support
  66. The consequences of seniors seeking health information using the internet and other sources.
  67. Proteomic analysis of rat cerebral cortex following subchronic acrolein toxicity
  68. Effect of aqueous extract of Crocus sativus L. (saffron) stigma against subacute effect of diazinon on specific biomarkers in rats
  69. From assessment to improvement of elderly care in general practice using decision support to increase adherence to ACOVE quality indicators: study protocol for randomized control trial
  70. Improving stroke prevention in patients with atrial fibrillation
  71. Effect of carbamazepine on homocysteine serum level in pregnant mice and fetal abnormalities
  72. Effect of carbamazepine on homocysteine serum level in pregnant mice and fetal malformations outcome

 

  • 2014 publications
  1. Usability Evaluation of Laboratory and Radiology Information Systems Integrated into a Hospital Information System
  2. Umbelliprenin induced production of IFN-gamma and TNF-alpha, and reduced IL-10, IL-4, Foxp3 and TGF-beta in a mouse model of lung cancer
  3. Ultrasensitive detection of lead (II) based on fluorescent aptamer-functionalized carbon nanotubes
  4. The protective effect of Nigella sativa against liver injury: a review
  5. The impact of computerized decision aid on mode of delivery - a study protocol
  6. The effect of curcumin on some of traditional and non-traditional cardiovascular risk factors: A pilot randomized, double-blind, placebo-controlled trial
  7. The effect of chronic administration of safranal on systolic blood pressure in rats
  8. Targeted Gene Delivery to MCF-7 Cells Using Peptide-Conjugated Polyethylenimine
  9. Synthesis of AS1411-Aptamer-Conjugated CdTe Quantum Dots with High Fluorescence Strength for Probe Labeling Tumor Cells
  10. Synthesis and biological evaluation of novel pyridine derivatives as potential anticancer agents and phosphodiesterase-3 inhibitors
  11. Surelease or organic solution of ethylcellulose in preparation of sustained release theophylline micromatrices or matrices using spray drying technique
  12. Surelease as granulating liquid in preparation of sustained release matrices of ethylcellulose and theophylline
  13. Serum Osteopontin Concentrations in Relation to Coronary Artery Disease
  14. Sensitive and fast detection of tetracycline using an aptasensor
  15. Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid
  16. Review of Plants and Their Constituents in the Therapy of Cerebral Ischemia
  17. Review of Pharmacological Effects of Myrtus communis L. and its Active Constituents
  18. Relationship between serum cytokine and growth factor concentrations and coronary artery disease
  19. Rabbit nasal immunization against influenza by dry-powder form of chitosan nanospheres encapsulated with influenza whole virus and adjuvants
  20. Proteomics screening of molecular targets of granulocyte colony stimulating factor in the mouse brain and PC12 cell line
  21. Protective effects of the aqueous extract of Crocus sativus against ethylene glycol induced nephrolithiasis in rats
  22. Protective effect of crocin on diazinon induced vascular toxicity in subchronic exposure in rat aorta ex-vivo
  23. Promising dissolution enhancement effect of soluplus on crystallized celecoxib obtained through antisolvent precipitation and high pressure homogenization techniques
  24. Preparation, evaluation and application of diazinon imprinted polymers as the sorbent in molecularly imprinted solid-phase extraction and liquid chromatography analysis in cucumber and aqueous samples
  25. Preparation of Effective and Safe Gene Carriers by Grafting Alkyl Chains to Generation 5 Polypropyleneimine
  26. Preparation of a pH-sensitive pantoprazole-imprinted polymer and evaluation of its drug-binding and -releasing properties
  27. Preparation and study of tramadol imprinted micro-and nanoparticles by precipitation polymerization: Microwave irradiation and conventional heating method
  28. Preparation and in-vitro Transfection Efficiency Evaluation of Modified Cationic Liposome-polyethyleneimine-plasmid Nanocomplexes as a Novel Gene Carrier
  29. Preparation and Evaluation of Histamine Imprinted Polymer as a Selective Sorbent in Molecularly Imprinted Solid-Phase Extraction Coupled with High Performance Liquid Chromatography Analysis in Canned Fish
  30. Preparation and characterization of spray-dried powders intended for pulmonary delivery of Insulin with regard to the selection of excipients
  31. Preparation and characterization of celecoxib solid dispersions; comparison of poloxamer-188 and PVP-K30 as carriers
  32. Preparation and characterization of celecoxib dispersions in soluplus((R)): comparison of spray drying and conventional methods
  33. Photochemical Behavior of Sethoxydim in the Presence of Vegetable Oils
  34. Neuroprotective effect of thymoquinone in acrylamide-induced neurotoxicity in Wistar rats
  35. Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin - A mini-review
  36. Morphine Reduces Expression of TRPV1 Receptors in the Amygdala but not in the Hippocampus of Male Rats
  37. Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases
  38. Minocycline potentiates the anti-hyperalgesic effect of ceftriaxone in CCI-induced neuropathic pain in rats
  39. Linalool as a neuroprotective agent against acrylamide-induced neurotoxicity in Wistar rats
  40. Involvement of central TRPV1 receptors in pentylenetetrazole and amygdala-induced kindling in male rats
  41. Inter-observer and Intra-observer Agreement in Pathological Evaluation of Non-alcoholic Fatty Liver Disease Suspected Liver Biopsies
  42. Insecticidal activity of the essential oil of Thymus transcaspicus against Anopheles stephensi
  43. Inhibitory effects of teuclatriol, a sesquiterpene from salvia mirzayanii, on nuclear factor-kappa B activation and expression of inflammatory mediators
  44. Inhibitory effect of Crocus sativus L. ethanol extract on adjuvant-induced arthritis
  45. Inhibitory Effect of Berberis vulgaris Aqueous Extract on Acquisition and Reinstatement Effects of Morphine in Conditioned Place Preferences (CPP) in Mice
  46. In vitro protective effects of Scutellaria litwinowii root extract against H2O2-induced DNA damage and cytotoxicity
  47. Health information-seeking behavior of seniors who use the internet: A survey
  48. Haloperidol imprinted polymer: preparation, evaluation, and application for drug assay in brain tissue
  49. Glutathione-S-Transferase M1 and T1 Null Genotypes Are Associated with Hypertension Risk: A Systematic Review and Meta-Analysis of 12 Studies
  50. From assessment to improvement of elderly care in general practice using decision support to increase adherence to ACOVE quality indicators: study protocol for randomized control trial
  51. Evaluation of Protein Ubiquitylation in Heart Tissue of Rats Exposed to Diazinon (an Organophosphate Insecticide) and Crocin (an Active Saffron Ingredient): Role of HIF-1alpha
  52. Evaluation of leishmanicidal effect of Euphorbia erythadenia extract by in vitro leshmanicidal assay using promastigotes of Leishmania major
  53. Evaluation of intravenous lipid emulsion on haloperidol-induced hypotension in rabbits
  54. Evaluation of 11 scoring functions performance on matrix metalloproteinases
  55. Evaluating the Effects and Safety of Intravenous Lipid Emulsion on Haloperidol-Induced Neurotoxicity in Rabbit
  56. Epithelial cell adhesion molecule aptamer conjugated PEG-PLGA nanopolymersomes for targeted delivery of doxorubicin to human breast adenocarcinoma cell line in vitro
  57. Efficacy of orally administered montmorillonite for acute iron poisoning detoxification in rat
  58. Effects of Intraperitoneal Thymoquinone on Chronic Neuropathic Pain in Rats
  59. Effects of chronic crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats
  60. Effect of Nigella sativa on ischemia-reperfusion induced rat kidney damage
  61. Effect of Nigella sativa fixed oil on ethanol toxicity in rats
  62. Effect Of Diabetes Mellitus On The Metabolism Of Drugs And Toxins
  63. Effect of cyanocobalamin (vitamin B12) in the induction and expression of morphine tolerance and dependence in mice
  64. Effect of Crocus sativus L. (Saffron) on Coagulation and Anticoagulation Systems in Healthy Volunteers
  65. Effect of aqueous extract of Crocus sativus L. (saffron) stigma against subacute effect of diazinon on specific biomarkers in rats
  66. Effect of aqueous and ethanolic extracts of Pimpinella anisum L. seeds on milk production in rats
  67. Effect of apple cider Vinegar on blood glucose level in diabetic mice (Article)
  68. Drug-drug interactions in inpatient and outpatient settings in Iran: a systematic review of the literature
  69. Development of ocular drug delivery systems using molecularly imprinted soft contact lenses
  70. Development of computerized clinical decision support to assist in detecting and preventing delirium in the hospital setting (Conference Paper)
  71. Design and fabrication of an aptasensor for chloramphenicol based on energy transfer of CdTe quantum dots to graphene oxide sheet
  72. Delayed combination therapy of local brain hypothermia and decompressive craniectomy on acute stroke outcome in rat
  73. Crocin, the main active saffron constituent, as an adjunctive treatment in major depressive disorder: A randomized, double-blind, placebo-controlled, pilot clinical trial
  74. Crocin improves lipid dysregulation in subacute diazinon exposure through ERK1/2 pathway in rat liver
  75. Crocin effects on human myeloma cells regarding intracellular redox state, DNA fragmentation, and apoptosis or necrosis profile
  76. Conformational switch of insulin-binding aptamer into G-quadruplex induced by K(+) and Na(+): an experimental and theoretical approach
  77. Comparing various techniques to produce micro/nanoparticles for enhancing the dissolution of celecoxib containing PVP
  78. Comparative evaluation of polymersome versus micelle structures as vehicles for the controlled release of drugs
  79. Clinical Applications of Saffron (Crocus sativus) and its Constituents: A Review
  80. Chrysin reduced acrylamide-induced neurotoxicity in both in vitro and in vivo assessments
  81. Central administration of GPR55 receptor agonist and antagonist modulates anxiety-related behaviors in rats
  82. Ceftriaxone, a Beta-Lactam Antibiotic, Modulates Apoptosis Pathways and Oxidative Stress in a Rat Model of Neuropathic Pain
  83. Carum induced hypothyroidism: an interesting observation and an experiment
  84. Brimonidine imprinted hydrogels and evaluation of their binding and releasing properties as new ocular drug delivery systems
  85. Blood bag temperature monitoring system
  86. Black cumin (Nigella sativa) and its constituent (thymoquinone): a review on antimicrobial effects
  87. Attenuation of oxidative stress, inflammation and apoptosis by ethanolic and aqueous extracts of Crocus sativus L. stigma after chronic constriction injury of rats
  88. Aptamer Biosensor for Selective and Rapid Determination of Insulin
  89. Antioxidant and Anti-Inflammatory Properties of the Citrus Flavonoids Hesperidin and Hesperetin: An Updated Review of their Molecular Mechanisms and Experimental Models
  90. Antilithiatic effects of crocin on ethylene glycol-induced lithiasis in rats
  91. Antidepressant Effect of Crocus sativus Aqueous Extract and its Effect on CREB, BDNF, and VGF Transcript and Protein Levels in Rat Hippocampus
  92. An imbalance in serum concentrations of inflammatory and anti-inflammatory cytokines in hypertension
  93. Alteration of protein profile in rat liver of animals exposed to subacute diazinon: A proteomic approach
  94. A study on druggability of MIA as a promising approach for inhibition of metastasis
  95. A review of the effects of Nigella sativa L. and its constituent, thymoquinone, in metabolic syndrome
  96. A Predictive HQSAR Model for a Series of Tricycle Core Containing MMP-12 Inhibitors with Dibenzofuran Ring
  97. A New Versatile Route to the Synthesis of a Novel Series of Highly Substituted 1,1 '-Carbonylbispyrazole Derivatives
  98. A fluorescent aptasensor for potassium ion detection-based triple-helix molecular switch
  99. A diagnostic model for cirrhosis in patients with non-alcoholic fatty liver disease: an artificial neural network approach
     

100. 8-pCPT, an Epac activator, impairs conditioned place preference based on nucleus accumbens amphetamine in rats

 

  • Books

Row

Title

Author

Published Date

1

Drug Bio-Pharmacy and Kinetics

Dr. Mohammad Hassanzadeh Khayat

1992

2

Instrumental Analysis Methods

Dr. Mohammad Hassanzadeh Khayat

2000

3

Pediatric Herbal Therapy

Dr. Mohammad Ramazani

2003

4

Side Effects of Medicinal Herbs (2nd edition)

Dr. Mohsen Tafaqodi

2004

5

Side Effects of Medicinal Herbs (1st edition)

Dr. Tafaqodi – Dr. Amiri

2004

6

Pharmaceutics (Science of Designing Medicinal Forms)

Dr. Afrasiabi – Dr. Tafaqodi – Dr. Sajjadi – Dr. Sadeqi

2005

7

Side Effects of Medicinal Herbs (1st edition)

Dr. Tafaqodi – Dr. Reza Amiri

2006

8

Side Effects of Medicinal Herbs (3rd edition)

Dr. Hosseinzadeh – Dr. Tafaqodi

2006

9

Pharmaceutics (2nd edition)

Dr. Afrasiabi – Dr. Tafaqodi ….

2006

10

Medicinal Biotechnology: Methods of Procuring and Medicinal Products of Biotechnology

Mohammad Ramazani

2007

11

Pediatric Herbal Therapy

Dr. Mohammad Ramazani

2008

12

Laboratory Guide to Molecular Biology

Dr. Ramazani – Dr. Mosafa – Dr. Parhiz – Dr. Montazeri

2009

13

Pharmaceutics: Science of Designing Medicinal Forms

Translators: Dr. Afrasiabi…

2010

14

The ABCs of Diabetes

Dr. Seyed Ahmad Mohajeri – Dr. Hosseinzadeh

2011

15

The Science of Designing Medicinal Forms

Dr. Afrasiabi

2014

 

             

 

ü  Theses

 

Dr. Imen Shahidi

Effects of Dexrazoxane on aluminum posphide cardiotoxicity in rats

Effects of curcumin on prevention of under chronic cardiovascular damages resulting from Bisphenol A in rats

Protective effects of alcohol extract of lemon verbena leaves and verbascoside effective material on indomethacin-induced peptic ulcer in rat

Protective effect of lemon verbena leaf aqueous extract on indomethacin-induced peptic ulcer in rat

Effects of acute Montmorillonite in acute lithium carbonate–induced toxicity in rat

Dr. Ramazani

DNA aptamer isolation for specific identification of PD-L1(CD274) and performance review

Targeted delivery of irinotecan via Aptamer-PEG-acetylated carboxymethyl cellulose complex to colorectal cancer cells

Electrospun nanofibers containing BMP-2 liposomal peptide to increase mesenchymal stem cell differentiation to bone

PLGA-based nanoparticles loaded with doxorubicin and targeted using PNC-27 peptide as a targeted anti-cancer system

Evaluation of targeted pharmaceuticals to breast cancer cells resistant to MCF/7MX drug using ABCG2 specific aptamer transporter

Effects of crocin and crocetin substances extracted from saffron on mesenchymal cell differentiation in bone cells

Effects of saffron-extracted crocetin and PLGA nanoparticles containing crocetin on incidence of multi-drug resistance phenotype

Procurement of antigen-containing exosomal nanocarriers for tumor treatment

Dr. Abnoos

DNA aptamer isolation for specific identification of PD-L1(CD274) and performance review

Carbon paste electrode-based electrochemical sensors modified using polymer molecule framework nanoparticles for determining Diazinon dosage

Targeted delivery of irinotecan via Aptamer-PEG-acetylated carboxymethyl cellulose complex to colorectal cancer cells

Evaluation of targeted pharmaceuticals to breast cancer cells resistant to MCF/7MX drug using ABCG2 specific aptamer transporter

PLGA-based nanoparticles loaded with doxorubicin and targeted using PNC-27 peptide as a targeted anti-cancer system

Procurement of antigen-containing exosomal nanocarriers for tumor treatment

Dr. Mehri

Effects of tropisetron on oxazaphosphorine-induced hemorrhagic cystic (cyclophosphamide or ifosfamide) in rat

Dr. Hosseinzadeh

Mechanism review of protective effects of crocin on cell toxicity resulting from oxidative stress in isolated hepatocytes in rat

Effects of crocin on human lymphocyte proliferation and Thelper1 and Thelper2 balance

Protective effects of Q10 co-enzyme on acrylamide-induced neurotoxicity in in vivo and in vitro models

Effects of safranal on metabolic disorders resulting from olanzapine consumption in rat

Anti-depressant effects of grape seed extract and resveratrol on postpartum forced swimming and depression model in mice

Effects of crocin on inducing phenotype switching of macrophages to anti-inflammatory M2 state

Effects of thymoquinone on D-galactose induced aging model in rat: memory disorders and its mechanisms

Effects of crocin on nerve damage induced by D-galactose induced aging model in cellular (SH-SS5Y) and animal (rat) environment

Anti-depressant effect of aqueous and ethanol extracts of lemon verbena leaves and its primary substance, verbascoside, on postpartum forced swimming and depression model in mice

Dr. Leila Etemad

Effects of cinnamic aldehyde on methamphetamine-induced nerve damage in PC12 cell

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

in vivo evaluation of aromatase enzyme inhibition using a new composition of 4-(1-imidazole-1-Il)methyl-2-4-methoxy-phenyl benzo quinoline in rat

Anticonvulsant effects of Suvorexant in mice

Effects of acute Montmorillonite on acute lithium carbonate-induced toxicity in rat

Effects of curcumin nanomicelles on phosphine-induced cell damage in HepG2 cell

Effects of pregabalin on nerve evolution using mouse embryonic stem cells

Dr. Seyed Adel Moalem

Effects of cinnamic aldehyde on methamphetamine-induced cell damage in PC12 cell

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

Effects of acute Montmorillonite on acute lithium carbonate-induced toxicity in rat

Effects of pregabalin on nerve evolution using mouse embryonic stem cells

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with potential biomarkers effecting atherosclerosis in patients suffering from chronic cardiac ischemia

Dr. Roohbakhsh

Effects of flavonoid dihydromirestin on expression and acquisition of CPP and symptoms of morphine-induced addiction in mice

Dr. Saeed Islami

 

Anti-depressant effects of saffron stigma in pregnant women suffering from postpartum depression

Anti-depressant effects of saffron stigma tablets on pregnant women suffering from non-major postpartum depression

Study on the relationship between NSAIDS consumption and gastrointestinal bleeding in patients with upper gastrointestinal bleeding referring to Qaem Hospital during 2014

Rational prescription of clozapine and prevalence of agranulocytosis in a sample from Ibn Sina Psychiatry Hospital of Mashhad.

Investigation of doctors prescribing behavior pregnant mothers regarding insurance prescriptions in Razavi Khorasan Province in order to assess inappropriate prescriptions of drugs during pregnancy and establish localized drug prescription instructions for pregnancy consistent with national status.

Relationship between anxiety and educational performance in Mashhad Pharmacy School students

Dr. Mohammad Hasanzadeh Khayat

Carbon paste electrode-based electrochemical sensors modified using polymer molecule framework nanoparticles for determining Diazinon dosage

 

Evaluation of serum concentrations of neopterin as an individual cardiovascular biomarker in patients suffering from coronary artery diseases

Amount of ethanol and methanol in alcohol-free beer brands in Iranian markets

Dr. Afrasiabi

Effects of different types and concentrations of plasticizers on characteristics of microcapsules from three different ethyl cellulose viscosities containing sodium diclophenac procured using emulsion-evaporation of solvent method

Procurement and evaluation of slow-release metoprolol microcapsules using eudragit RS polymers and ethyl cellulose

Performance review of Carr’s Index and Hausner Ratio for determining characteristics of powder flows and evaluating the effects of factors such as powder particle size and type and amount of glidant on these indicators

Comparison of the effects of nerolidol and oleic acid as an enhancer for skin permeability of diclophenac D –ethyl amine in patches provided using R-L eudragit base

Dr. Amir Hooshang Mohamadpoor

Study of the relationship between coronary artery calcification and carotid intima-media thickness (IMT) with decorin and biglycan biomarkers in patients suffering from chronic cardiac ischemia

Evaluation of serum concentrations of neopterin as an individual cardiovascular biomarker in patients suffering from coronary artery diseases

Effects of topical creams containing honey and aloe vera in treatment of radiotherapy-induced dermatitis in breast cancer patients

Dr. Seyed Ahmad Mohajeri

Evaluation of vitamin A suppositories for vaginal use

Protective effects of crocin and corcetin against hyperglycemic damage in retina cells

Procurement of fluorometholone molecular molded hydrogels as ocular drug delivery systems and investigation of binding properties of the drug and its release into the environment

 

 

 

 

ü  Main activities

  • Screening teratogenic effects of chemical substances and medicinal herbs
  • Analytical toxicology of nutrients
  • Synthesis and analysis of drug derivatives
  • Basic researches on modern drug delivery systems (liposomes, nanospheres)
  • Isolation and purification of active herbal compounds
  • Investigating pharmacological effects of medicinal herbs and their synthetic derivatives

 

ü  Equipment:

 

  • Department of Nanomedicine

Supervisor: Dr. Mohammadreza Ramazani (Professor of Medicinal Biotechnology)

Equipment include: MPLC, refrigerated centrifuge, optical microscope, UV cabinet, vacuum centrifuge, ELISA reader, freeze dryer, all equipment required for column chromatography and TLC, sonicator, solvent removal device, and soxhlet device. Four computers with high-speed internet along with scanner and printer.

 

  • Department of Analysis

Supervisor: Dr. Mohammad Hassanzadeh Khayat (Professor of Medicinal Chemistry)

Equipment include: UV-VIS spectrophotometer, infra-red spectrophotometer, spectrofluorimeter device, high performance liquid chromatography device (HPLC) for analysis of different substances (qualitatively and quantitatively). 2 computers with internet access.

 

  • Department of Pharmacodynamics

Supervisor: Dr. Hossein Hosseinzadeh (Professor of Pharmacology)

Equipment include: HPLC device, Power Lab device, solvent removal device, hot plate, water maze (MWM), dry heater, oven, microscope with computer connective camera, centrifuge, digital scale, stereotaxy, etc.  Four computers with high-speed internet and one printer.

 

  • Department of Toxicology and Teratology

Supervisor: Dr. Seyed Adel Moalem (Professor of Toxicology)

Equipment include: tom mice fetus and organ culture device, several stereomicroscopes and digital imaging system for investigating fetal abnormalities, microtome, laminar hood, CO2 incubator and invert microscopes for cell culture, ELISA device, spectrophotometer, PCR gradient device, gel sequencing device, electrophoresis device for studying DNA, RNA, and proteins, and liquid nitrogen tanks for long-term preservation of cells. Two computers with high-speed internet along with two printers.



 

       

  

 

 

 

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Last Name:

First Name:

Eslami (Hassanabadi)

Saeid

 

E-mail address:

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Personal Information

Marital status: Married

Birth date: 02-05-1974/12-02-1353

Place of Birth: Mashhad, Iran

 

Education

Ph.D. and Research Fellow

2004-2012                 Department of Medical Informatics, Faculty of Medicine,

                                  University of Amsterdam, Amsterdam, The Netherlands

Thesis title: “Pharmacotherapy and patient safety in intensive care: impact of guideline-base decision support”

 

Fellowship 1: Safety & quality of care in intensive care

 

Fellowship 2: Safety & quality of care of elderly

 

 

Pharm.D. (Doctor of Pharmacy)

1992-2000                      School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IRAN

Thesis title: “Design and Programming Multimedia database of drug information for the Iranian formulary”

 

Technical Experience

ü  Programming with Visual Basic 6 (professional level), particularly medical and pharmaceutical applications.

ü  Database programming with Visual Basic 6 and SQL

ü  Network Design with Windows NT & Advanced Server 2000 (good level)

ü  Hardware and computer assembly (level: good)

 

 

Teaching Experience

ü  Computer applications in pharmacy (for Ph.D. students in pharmaceutical sciences), 2000-2001

ü  Informatics and Internet (for Ph.D. students in pharmaceutical sciences), 2000-2001

ü  Computer applications in pharmacy and medicine (for Pharm.D. students), 1998-2000

ü  Computer application in dentistry and medicine (for D.D.S. students), 2000

ü  Information and Internet (for Pharm.D. students), 1997-2000

ü  Evaluation of decision support application (Medical informatics students), Amsterdam, 2007-2009

ü  Supervising and co-supervising two Medical Informatics master students, Amsterdam, 2008-2009

ü  Evaluation in Medical Informatics (Medical informatics Ph.D. students), Mashhad, 2011-

ü  Management of Medical Informatics Projects (Medical informatics Ph.D. students), Mashhad, 2011-

ü  Information and Information Sources in Medicine (Ph.D. students), Mashhad, 2012-

ü  Information and Information Sources in Medicine (M.Sc. students), Mashhad, 2012-

ü  Hospital Pharmacy (Pharm.D. students), Mashhad, 2012-

ü  Statistics (Toxicology M.Sc. student) , Mashhad, 2012-

ü  Research design and informatics (Toxicology Ph.D. students), Mashhad, 2012-

ü  Computer (Toxicology Ph.D. students), Mashhad, 2012-

ü  Applied projects (Medical informatics M.Sc. students), Mashhad, 2012-

ü  Decision Support systems (Medical informatics M.Sc. students), Mashhad, 2012-

ü  Statistics by non-mathematical approach, Workshop, Mashhad, 2012

ü  Systematic review, Workshop, Mashhad, 2012

ü  Supervising and co-supervising more than 10 Medical Informatics Ph.D. and Master students, 2012-

ü  Supervising and co-supervising more than 5 pharmacy and medical doctorate student, 2012

ü  …

 

 

Awards

ü  Third prize of Health and Hygiene group in 20th Razi Medial Science Festival, Iran, 2014

ü   Third prize of the Academic Medical Center’s safety projects, Amsterdam, The Netherlands, 2007

ü  Honor Researcher in Medical Informatics at Mashhad University of Medical Sciences, Mashhad, IRAN, 2002

ü  IT Consultant for President of Khorasan Province Food & Drug Administration, Mashhad, IRAN, 2001-2004

ü  Member of Information Technology Committee of Mashhad University of Medical Sciences, Mashhad, IRAN, 2000-2004

ü  Honor Student in Medical Informatics at Mashhad University of Medical Sciences, Mashhad, IRAN, 1998

 

 

Research Projects

ü  Designing a Clinical Registry for ICU Patients and Adopting, Calibrating and Validating APACHE and SAPS Mortality Prediction Models for Intensive Care Units in Iran, 2013-

ü  Designing and Evaluating of an E-learning System for Pharm.D. Students on Reading the Medications in the  Prescriptions, 2013-

ü  Effect of drug therapy on the continuity of care of patients with depressive and/or stress disorders, 2013- 

ü  Designing and Evaluation of Feedbacks Based on Decision Support System on Frequency of Drug-Drug Interactions among Prescriptions in Mashhad, 2013-

ü  Evaluation of the quality of pharmaceutical services in community pharmacies, sources of information and level of knowledge of pharmacists in Mashhad and suggesting reform plans, 2013-

ü  Evaluating the sufficiency of  the ultrasonography reports of patients suspected to NAFLD and developing a valid structured Reporting model, 2013-

ü  Effective factors in information exchange between patient and physician and suggesting IT based interventions to improve, 2013-

ü  Empowering pregnant woman by IT Interventions, 2012-

ü  Clinical decision support system for diagnosis of patients with Non-Alcoholic Fatty Liver Disease (NAFLD), 2012-

ü  Designing and evaluation of an IT-Based feedback system to change the behavior of general practitioners of Kerman province to reduce inappropriate parenteral corticosteroids prescription, 2012-

ü  Designing a registry for occupational hazards in hospitals and investigating the effect of reforms in the way of informing and education on clinical staff safety, 2012-

ü  Improving Care of Vulnerable Elders (ICOVE), 2009-

ü  Effect of four levels of computerized decision support (from non-critiquing and patient non-specific till critiquing and patient-specific) on adherence to aminoglycoside guideline; and frequency of errors and adverse drug events, 2004-

ü  Effect of two levels of decision support on antibiotics prescription - effectiveness and cost-benefit, 2004-

ü  Effect of a critiquing and non-critiquing decision support system for different target groups (physicians, nurses and both) on adherence to lung protective mechanical ventilation strategy, 2005-2011

ü  Effect of two levels of decision support (patient non-specific, patient specific) on adherence to guideline and glucose regulation, 2005-2011

ü  Systematic literature reviews on CPOE in outpatients, CPOE in inpatients, quality indicators for glucose regulation, decision support for glucose regulation, 2004 -2012

ü  Design and development of simulator software for reading prescriptions  in pharmacies, 1998-2000

ü  Design and Programming a Windows-based software for Iranian Outpatient- and Inpatient-Pharmacies, 1994-2004

ü  Design and Programming multimedia database of drug information for the  Iranian formulary, 1998

ü  Design and Programming a Windows-based software for libraries of Mashhad University of Medical Sciences, Mashhad, IRAN, 1996

 

 

Courses and Workshops

ü  Decision Support Systems, Mashhad, Iran, Sep 2012

ü  Electronic Health Records, Mashhad, Iran, Sep 2012

ü  Statistics in Medicine, Mashhad, Iran, Sep 2012

ü  Great Survey Design, Amsterdam, The Netherlands, July 2012 – August 2012

ü  ATC/DDD methodology (organized by WHO), Oslo, Norway, June 2012

ü  Epidemiolgy (organized by European Renal Association - European Dialysis and Transplant Association), Amsterdam, The Netherlands, Jan-Feb 2012

ü  Better use of PubMed, Amsterdam, The Netherlands, Jan 2012

ü  Statistical computing in R, Amsterdam, The Netherlands, Nov 2011

ü  Longitudinal studies, Amsterdam, The Netherlands, 2010

ü  Prognostic models, Amsterdam, The Netherlands, 2010

ü  Introduction to Bioinformatics, Amsterdam, The Netherlands, Feb 2009

ü  Erasmus summer programme, Rotterdam, The Netherlands, Aug 13-31, 2007

-          Clinical Trials

-          Regression Analysis

-          Pharmaco-epidemiology

-          The why and how of readable articles

ü  Advanced Bio-statistics Amsterdam, The Netherlands, Sept 4-Oct 5, 2006

ü  Practical Bio-statistics, Amsterdam, The Netherlands, Oct-Nov, 2005

ü  Oral Presentation in English, Amsterdam, The Netherlands, 2005

ü  Scientific Writing in English for Publication-Writing to be read, Amsterdam, The Netherlands, Oct-Dec, 2005

ü  International Masterclass for Medical Informatics, Heidelberg/Heilbornn/Bad Wimpfen, Germany, July 16-20, 2005

ü  Health Informatics: the role of informatics in health care- the Amsterdam International Medical Summer School, Amsterdam, The Netherlands, July 11-23, 2004

ü  The Netherlands Medical Informatics Ph.D. days:

-          Utrecht, Jan, 2005

-          Mastricht, Jan, 2006

-          Nijmegen, Feb, 2007

-          Zeeland, March, 2008

-          Amsterdam, Jan, 2009

-          Zeeland, March, 2010

-          Amsterdam, March 2011

-          Breukelen, March 2014

 

 

Superviser or Co-superviser

SarafiNejad A, Designing and evaluation of an IT-Based feedback system to change the behavior of general practitioners of Kerman province to reduce inappropriate parenteral corticosteroids prescription-Using SMS, Medical Informatics PhD Thesis, Iran
Nabovati E, Designing and Evaluation of Feedbacks Based on Decision Support System on Frequency of Drug-Drug Interactions among Prescriptions in Mashhad, Medical Informatics PhD Thesis, Iran
Sarbaz M, Designing a web-based registry for occupational incidents in hospitals and investigating the effect of reforms in the way of informing and education on clinical staff safety, Medical Informatics PhD Thesis, Iran
Aslani A, Effects of Information Technology (information system and decision aid) on Empowering Pregnant Woman- Mashhad, 2012, Medical Informatics PhD Thesis, Iran

Pournik O, Computerized decision support system for non alcoholic fatty liver disease diagnosis, Medical Informatics PhD Thesis, Iran (First Iranian graduated student in PhD of Medical Informatics)

Aamer, PharmD Thesis, Iran

Askari M., Investiagting drug-drug interactions and preventing them by a decision support system, Medical Informatics Master Thesis, The Netherlands

Opondo D., Assessing the quality of care for the elderly in gereral practice. Medical Informatics Master Thesis, The Netherlands (selected as the best Medical Informatic Master thesis in 2011 in the Netherlands)

Publications

 

ISI publications

 

1)      Eslami S, Sahebkar A. Glutathione-S-transferase M1 and T1 null genotypes are associated with hypertension risk: a systematic review and meta-analysis of 12 studies. Current hypertension reports. 2014;16(6):432.

2)      Van de Glind EM, Willems HC, Eslami S, Abu-Hanna A, Lems WF, Hooft L, et al. Estimating the Time to Benefit for Preventive Drugs with the Statistical Process Control Method: An Example with Alendronate. Drugs & aging. 2016.

3)      Wlodzimirow KA, Eslami S, Chamuleau RA, Nieuwoudt M, Abu-Hanna A. Prediction of poor outcome in patients with acute liver failure-systematic review of prediction models. PloS one. 2012;7(12):e50952.

4)      Askari M, Eslami S, Medlock S, de Rooij SE, Abu-Hanna A. Fall-related Information seeking behavior of seniors on the web. Studies in health technology and informatics. 2014;205:647-51.

5)      Wlodzimirow KA, Eslami S, Abu-Hanna A, Nieuwoudt M, Chamuleau RA. A systematic review on prognostic indicators of acute on chronic liver failure and their predictive value for mortality. Liver international : official journal of the International Association for the Study of the Liver. 2013;33(1):40-52.

6)      Sahebkar AH, Eslami S. Glutathione-S-Transferase M1 and T1 Null Genotypes Are Associated with Hypertension Risk: A Meta-Analysis of 12 Studies. Current Hypertension Reports 2014, Accepted.

7)      Eslami S et al. From assessment to improvement of elderly care in general practice using decision support to increase adherence to ACOVE quality indicators: study protocol for randomized control trial. Trials 2014, 19;15(1):81.

8)      Nabovati E, Vakili-Arki, H, Eslami S, Khajouei R. Usability Evaluation of Laboratory and Radiology Information Systems Integrated into a Hospital Information System. Journal of Medical Systems 2014, 38:35.

9)      Pournik O, …, Eslami S. A Diagnostic Model for Cirrhosis in Non-Alcoholic Fatty Liver Disease Patients; An Artificial Neural Network Approach. Med J Islamic Republic of Iran 2014, Accepted.

10)  Pournik O, ..., Eslami S. Inter-observer and Intra-observer Agreement in Pathological Evaluation of Non-alcoholic Fatty Liver Disease Suspected Liver Biopsies. Hepat Mon. 2014 January; 14(1): e15167.

11)  Askari M, …, Eslami S et al. Verschil in geneesmiddelengebruik tussen ouderen met een eenmalige val versus frequente vallers (in Dutch). Nederlands Tijdschrift voor Geneeskunde 2014, Accepted.

12)  Arts DL, …, Eslami S, van Weert HCPM. Improving stroke prevention in patients with atrial fibrillation. Trials 2013, 14:193.

13)  Pournik O, ..., Eslami S. Lower intrafamilial transmission rate of hepatitis B in patients with hepatitis D coinfection : A Data-mining approach. Hepatitis Monthly 2013. Accepted

14)  Medlock A, Eslami S et al. Co-prescription of gastroprotective agents and their efficacy in elderly patients taking nonsteroidal anti-inflammatory drugs: a systematic review of observational studies. Gasteroentrology and hepatitis 2013. Accepted.

15)  Askari M, Eslami S et al. Different risk-increasing drugs in recurrent versus single fallers: are recurrent fallers a distinct population? Drugs and Aging 2013, Accepted

16)  Askari M, …, Eslami S et al. A combined disease management and process modeling approach for assessing and improving care processes: A fall management case-study. Int J Med Inform, Accepted

17)  Askari M, Eslami S et al. Frequency and nature of Drug-drug Interaction in the Intensive Care Unit. Pharmacoepidemiology & Drug Safety 2013; Accepted.

18)  Pournik O, Alavian SM, Eslami S. Can We Accurately Assess Liver Fibrosis with Fibroscan® Using Fewer Valid Measurements? Yonsei Med J; Accepted.

19)  Wlodzimirow KA, Eslami S et al. Prediction of poor outcome in patients with acute liver failure-systematic review of prediction models. PLoS ONE  2012; 7(12).

20)  Opondo D, Eslami S et al. Inappropriateness of medication prescriptions to elderly patients in primary care: A Systematic Review. PLoS ONE 2012; 7(8).

21)  Wlodzimirow KA, Eslami S et al. Systematic review: acute liver failure - one disease, more than 40 definitions.  Alimentary Pharmacology & Therapeutics 2012; 35(11):1245-56

22)  Wlodzimirow KA, Eslami S et al. A Systematic Review on prognostic indicators of human Acute on Chronic Liver Failure and their predictive value for mortality. Liver International 2013; 33(1):40-52

23)  Minne L, Eslami S et al. Five years of therapeutic drug monitoring in the intensive care did not change vancomycin prescription behaviour: perceived needs for decision support. Minerva Anestesiologica 2012 Jun;78(6):684-92

24)  Wlodzimirow KA, Eslami S et al. Acute liver failure – What is it? Hepatology 2012; 55(4):1306-7.

25)  Minne L, Eslami S et al. Statistical process control for monitoring standardized mortality ratios of a classification tree model. Methods Inf. Med. 2012;51(4):353-8

26)  Askari M, Wierenga P, Eslami S et al. Assessing Quality of Care of Elderly patients using the ACOVE quality indicator set: A Systematic Review PLoS ONE 2011; 6(12):e2863.

27)  Meynaar IA, Eslami S et al. Blood glucose amplitude variability as predictor for mortality in surgical and medical ICU patients - A multicenter cohort study. J Crit Care 2012; 27(2):119-24

28)  Eslami S et al. Effects of two different levels of computerized decision support on blood glucose regulation in critically ill patients. Int J Med Inform 2011, 81(1):53-60

29)  Minne L, Eslami S et al. Statistical Process Control for validating a classification tree model for predicting mortality - a novel approach towards temporal validation. J Biomedical Informatics 2011; 45(1):37-44

30)  Eslami S et al. Evaluation of consulting and critiquing decision support         systems: Effect on adherence to a lower tidal volume mechanical ventilation strategy. J Crit Care 2012 Aug;27(4):425.e1-8

31)  Askari M, Wierenga PC, Eslami S, et al. Studies Pertaining to the ACOVE Quality Criteria: A Systematic review. Int J for Qual in Health Care 2011; 24(1):80-7

32)  Minne L, Eslami S et al. Effect of changes over time in the performance of a customized SAPS-II model on quality of care assessment. Intensive Care Medicine 2012; 38(1):40-6

33)  Medlock S, Eslami S et al. Improved communication in post-ICU care by improving writing of ICU discharge letters: a longitudinal before-after study. BMJ Quality & Safety 2011; 20(11):967-73

34)  Medlock S,  Opondo D, Eslami S, Askari M, Wierenga P, de Rooij SE, Abu-Hanna A. LERM (Logical Elements Rule Method): A method for assessing and formalizing clinical rules for decision support. Int. J of Med Inform.  2011;  80(4):286-95.

35)  Eslami S, Taherzadeh Z, Schultz MJ, Abu-Hanna A. Glucose variability measures and their effect on mortality – A systematic review. Intensive Care Med. 2011; 37(4):583-93.

36)  Eslami S, Abu-Hanna A. Acceptance of drug-drug interaction alerts and alert system design. Br J Clin Pharmacol. 2010 Oct;70(4):619-20.

37)  Eslami S, Abu-Hanna A, de Keizer NF, Bosman RJ, Spronk PE, de Jonge E, Schultz MJ. Implementing glucose control in intensive care: a multicenter trial using statistical process control. Intensive Care Med. 2010 Sep;36(9):1556-65.

38)  Eslami S, Abu-Hanna A, de Jonge E, de Keizer NF. Tight glycemic control and clinical decision support – A systematic review. Intensive Care Medicine.2009 Sep;35(9):1505-17.

39)  Eslami S, de Keizer NF, de Jonge E, Schultz M, Abu-Hanna A. A systematic review on quality indicators for tight glycaemic control in critically ill patients; the need for unambiguous indicator reference subset. Critical Care 2008;, 12:R139.

40)  Eslami S, Abu-Hanna A, de Keizer NF, de Jonge E, Schultz M. Effect of a clinical decision support system on adherence to a lower tidal volume mechanical ventilation strategy. Journal of Critical Care 2009; 24(4):523-9.

41)  Eslami S, de Keizer NF, Abu-Hanna A. The impact of computerized physician medication order entry in hospitalized patients - A systematic review. Int. J of Med Inform. 2008; 77(6):365-76.

42)  Eslami S, Abu-Hanna A, de Keizer NF. Evaluation of outpatient computerized physician medication order entry systems: a systematic review. J Am Med Inform Assoc. 2007 Jul-Aug;14(4):400-6.

43)  Eslami S, Abu-Hanna A, de Keizer NF, de Jonge E. Errors associated with applying decision support by suggesting default doses for aminoglycosides. Drug Saf. 2006;29(9):803-9.

 

Medline indexed publications

44)  Aslani A, …, Eslami S. Pregnant women's information seeking. Stud Health Technol Inform. 2014; Accepted.

45)  Hejazi Y, …, Eslami S. e-Learning System for PharmD Students-Feasibility and Preliminary Result of a Randomized Controlled Trial. Stud Health Technol Inform. 2014; Accepted.

46)  Pournik O, …, Eslami S. Evaluation of a Computer-based Clinical Decision Support System on physician performance and patient outcome of Non-Alcoholic Fatty Liver Disease Patients. Stud Health Technol Inform. 2014; Accepted.

47)  Aalaei S, …, Eslami S. Blood BagTemperature Monitoring System. Stud Health Technol Inform. 2014; Accepted.

48)  Aslani A, …, Eslami S. Web-site Evaluation Tools: Reproductive Health Information. Stud Health Technol Inform. 2014; Accepted.

49)  Askari M, Eslami S et al. Fall-related Information seeking behavior of seniors on the web. Stud Health Technol Inform. 2014; Accepted.

50)  Aslani A, …, Eslami S. The impact of a computerized decision aids on   mode of delivery-Study protocol. Stud Health Technol Inform. 2014; Accepted.

51)  Medlock S, Eslami S et al. The Consequences of Seniors Seeking Health Information Using the Internet and Other Sources. Stud Health Technol Inform. 2013; Accepted

52)  Medlock S, Eslami S et al. Attitudes and Experience of Dutch General Practitioners Regarding Computerized Clinical Decision Support. Accepted. Stud Health Technol Inform. 2013;186:56-60.

53)  Askari M, Eslami S, et al. Relevance of drug-drug interaction in the ICU - Perceptions of intensivists and pharmacists. Stud Health Technol Inform.  2012;180:716-20

54)  Medlock S, Eslami S, et al. Application of the Logical Elements Rule Method for formalization of clinical rules: case study of ACOVE-NLI. Stud Health Technol Inform. 2012;180:421-6

55)  Abu-Hanna A, Eslami S, Schultz MJ, de Jonge E, de Keizer NF. Analyzing effects of providing performance feedback at ward rounds on guideline adherence - the importance of feedback usage analysis and statistical control charts. Stud Health Technol Inform. 2010;160:826-30.

56)  Tavakkoli M, ..., Eslami S. Omega-3 and Omega-6 Content of Medicinal Foods for Depressed Patients: Implications from the Iranian Traditional Medicine. Avicenna J of Phytomedicine 2014, Accepted.

Embase indexed publications

57)  Wlodzimirow KA, Eslami S et al. A systematic review on prognostic indicators of acute liver failure and their predictive value for poor outcome. British Journal of Medicine & Medical Research. 2014; 4(15):2796-2852.

58)  Medlock S, Eslami S et al. Health information seeking behavior of elderly Internet users in the Netherlands. European Geriatric Medicine 2012; 3 (pp S90-S91) (8th Congress of the European Union Geriatric Medicine Society Brussels Belgium).

59)  Eslami S, Abu-Hanna A, de Keizer NF, de Jonge E, Schultz M. Decision support to increase adherence to a mechanical ventilation guideline: A study protocol and first results. Intensive Care of Medicine 2008; 34 (pp S78) (21st Annual Congress of the European Society of Intensive Care Medicine, ESICM Lisbon Portegal).

60)  Eslami S., De Keizer N.F., Taherzadeh Z., Schultz M.J., Abu-Hanna A. Tight glycaemic control and computerized decision support systems-future and challenges. Diabetes Technology and Therapeutics 2011; 13 (2) (pp 182). (4th International Conference on Advanced Technologies and Treatments for Diabetes, ATTD 2011 London United Kingdom).

61)  Eslami S., Abu-Hanna A., De Keizer N.F., De Jonge E., Dongelmans D., Schultz M.J. Effects of two levels of computerized decision support on glucose regulation in intensive care-using statistical process control. Intensive Care Medicine 2009; 35  (pp S236). (22nd Annual Congress of the European Society of Intensive Care Medicine, ESICM Vienna Austria).

62)  Eslami S., De Keizer N.F., De Jonge E., Abu-Hanna A. Improving medication safety in the intensive care unit by implementing computerized decision support system-using statistical process control. Intensive Care Medicine 2009; 35  (pp S235). (22nd Annual Congress of the European Society of Intensive Care Medicine, ESICM Vienna Austria).  

63)  Eslami S., Abu-Hanna A., De Keizer N.F., Bosman R.J., Spronk P.E., De Jonge E., Schultz M.J. Implementing Glucose regulation guidelines in intensive care - A multicenter trial using statistical process control. Basic and Clinical Pharmacology and Toxicology 2009; 105  (pp 33-34). (9th Congress of the European Association for Clinical Pharmacology and Therapeutics Edinburgh United Kingdom). 

Other publications

64)  Eslami S et al. Lessons learned from implimentating and evaluating computerized decision support systems. Lecture Notes in Artificial Intelligence 2011; 6747:101-108

65)  Medlock S, Eslamia S, Askaria M, de Rooijb S, Abu-Hanna A. Improving Care Of Vulnerable Elders (ICOVE): the road from quality indicators to quality improvement.  VMBI Yearbook 2010.

66)  Eslami S, de Keizer NF, Schultz MJ, de Jonge E, Abu-Hanna A. Pharmacotherapy and patient safety in intensive care-Impact of guideline-based decision support. VMBI Yearbook 2009; 17-21.

67)  Eslami S. (2009) Pharmacotherapy and patient safety in intensive care-Impact of guideline-based decision support. Amsterdam: Ponsen & Looije.

Submitted and ready to submit manuscripts

68)  Amenability of ACOVE quality indicators for automatic evaluation in general practice care in the Netherlands

69)  The association between blood glucose variability and hospital mortality is dependent on the blood glucose control guideline in use

70)  From assessing to improvement – Protocol of a randomized control trial using ACOVE quality indicators to improve quality of elderly care in outpatient setting

71)  A multi-center study on end-of-life decision-making in the Intensive Care: Differences between physicians’ perceptions and clinical practice

72)  Improving stroke prevention in atrial fibrillation – Protocol of A RCT study

73)  Impact of half-life definitions between drug administration times on frequency of DDIs - A novel step toward detecting relevant DDIs

74)  Influence of electronic medical record systems on physicians response to drug safety warnings

75)  Three or more valid measurements for assessing liver fibrosis using FibroScan® in Patients with Chronic Viral Hepatitis

76)  Feasibility of automatic evaluation of quality of care based on quality indicators in general practice

77)  For which tasks do doctors want decision support, and why? A survey of Dutch general practitioners.

78)  …

 

Presentations in seminars

ü  Prognostic models for benchmarking-adaptation and implementation. 3rd Conference on Health Tourism in Islamic Countries, Mashhad, December 2012

ü  Web-site Evaluation Tools: Reproductive Health Information. 13th International Congress of Gynecology & Obstetrics, Tehran, December 2012 (co-author)

ü  Eight Years’ Experience in Designing, Implementation and Evaluation of Computerized Decision Support Systems in the Netherlands – Futures and Challenges; and Lessons Learned for Iran, 1st International Conference on Electronic Health, Tehran, November 2012

ü  Lessons learned from designing, implementing and evaluating decision support system, 1st Seminar on Intelligent Laboratory, Tehran, November 2012

ü  Met Statistical Process Control (SPC) kan de time-to-benefit van preventieve medicatie gemakkelijk en inzichtelijk bepaald worden.  Een voorbeeld met alendronaat. (in Dutch, co-author)

ü  Health information seeking behavior of elderly internet users in the Netherlands, EUGMS, Brussels, Sept 2012 (co-author)

ü  Fall-related information seeking behavior among elderly internet-users 21st Nordic Congress of Gerontology - Dilemmas in Ageing Societies, Copenhagen, June 2012 (co-author)

ü  Lessons learned from implimentating and evaluating computerized decision support systems, Artificial Intelligence in Medicine (AIME), Bled, 2011

ü  ??, International Forum on Quality and Safety in Health Care, Amsterdam, 2010 (co-author)

ü  Tight Glycaemic Control and Computerized Decision Support Systems – future and challenges (invited speaker), Advanced Technologies & Treatments for Diabetes (ATTD), London, 2011

ü   Implementing Glucose Regulation guidelines in Intensive Care – A Multicenter trial Using Statistical Process Control, The 9th Congress of the European Association for Clinical Pharmacology and Therapeutics, Edinburgh, 2009

ü  Critiquing vs. non-critiquing decision support: Effect on adherence to a lung-protective mechanical ventilation protocol, 10th Congress of WFSICCM, Florence, 2009

ü  Effects of two levels of computerized decision support on glucose regulation in intensive care –Using statistical process control, European association of Intensive Care Medicine (ESICM), Vienna, 2009

ü  Improving medication safety in the intensive care unit by implementing computerized decision support system- Using statistical process control, European association of Intensive Care Medicine (ESICM), Vienna, 2009

ü  Decision support to increase adherence to a mechanical ventilation guideline: a study protocol and first results, European association of Intensive Care Medicine (ESICM), Lisbon, 2008

ü  Can Default Dose Introduce New Source of Errors, International Forum on Quality and Safety in Health Care, Barcelona, 2007

ü  Multimedia Database of Iranian Drugs Interactions, 16th Iranian Congress of Physiology & Pharmacology, Tehran, 2003

ü  Simulator software for prescription reading in pharmacies, 8th Iranian Pharmaceutical Sciences Seminar, Shiraz, 2002

ü  Reform of drug distribution in hospitals with computer, 1th Food and Drug Usage Seminar, Sari, 2000

ü  Multimedia searcher for pharmaceutical and toxic agents in Iran, 6th Iranian Toxicology and Drug Poisoning Congress , Ahvaz, 1999

ü  Lecturer in various continuing education courses for Iranian pharmacists, topics include computer applications in pharmacy, 1999-2004

ü    Multimedia database of drug information in Iranian formulary, 5th Iranian Pharm.D. Student Seminar, Tehran, 1999

ü  Education Technology in Iran, 5th Iranian Pharm.D. Student Seminar, Tehran, 1999

ü  Multimedia database of Iranian medicinal plants, 1th Medicinal Plant and Industry, Tehran, 1997

ü    Antimicrobial activity of Iranian plant (Khorasan province), 3th Iranian Pharm.D. Student Seminar, Tehran, 1996

ü    Library management software, 2th Iranian Phrm.D. Student Seminar, Mashhad, 1995

ü  Anti HIV drug advice,1th Iranian Pharm.D. Student Seminar, Tabriz, 1994

ü    Design of Iranian plant systematic poster, 1th Iranian Pharm.D. Student Seminar, Tabriz, 1994

 

Membership

ü  Presidency of Islamic Republic of Iran National Elites Foundation, 2016-

ü  Dutch Association of Medical Informatics, 2008-

 

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Mohsen Tafaghodi (Pharm.D., Ph.D.)

 

Professor in Pharmaceutics and Nanotechnology

 

 

Address:

School of Pharmacy,

Nanotechnology Research Center,

Mashhad University of Medical Sciences,

Mashhad-Iran

Tel: ++98-51-38823255-66 (Office)

Fax: ++98-51-38823251

tafaghodim[at]mums.ac.ir

Updated at:  June 2016                         

                                                       und Educational Background 

Pharm.D.: School of Pharmacy, Mashhad University of Medical Sciences (1991-1997).

Ph.D. (Pharmaceutics): School of Pharmacy, Mashhad University of Medical Sciences (1997-2003). Ph.D. thesis title: Nasal immunization using biodegradable microspheres and liposomes: Tetanus toxoid as a model

 

Research fellowships:

1-      School of Pharmacy, University of Alberta, Canada (cancer vaccination using nano- and microparticulate drug delivery systems). 2001.

2-      Leiden/Amsterdam center for Drug Research, University of Leiden, Netherland (preparation and characterization and in vivo study of TMC:HBsAg and chitosan:HBsAg nanoparticles as a nasal delivery /adjuvant system). 2011.

 

 

 

Research Interests

Mucosal and systemic vaccine and drug delivery by nanoparticulate and microparticulate delivery systems (nanospheres, microspheres and liposomes)

 

 

 

 

Publications

Books

1. Tafaghodi, M., Amiri, R., Hosseinzadeh, H., 1998. Adverse Effects of Herbal Drugs. Volume 1, MUMS Press, Mashhad. (Translation), 4th print 2007.

2. Tafaghodi, M., Hosseinzadeh, H., 2002. Adverse Effects of Herbal Drugs. Volume 2, MUMS Press, Mashhad. (Translation), 3rd print, 2007.

3. Hosseinzadeh, H., Tafaghodi, M., 2006. Adverse Effects of Herbal Drugs. Volume 3, MUMS Press, Mashhad. (Translation).

4. Afrasiabi, H., Tafaghodi, M., Sajadi, S.A., Sadeghi, F., 2006. Pharmacetics, the science of dosage form design. Volume 1, MUMS Press, Mashhad. (Translation, 2nd print, 2009).

5. Afrasiabi, H., Tafaghodi, M., Sajadi, S.A., Sadeghi, F., Fazly, B.S., 2007. Pharmacetics, the science of dosage form design. Volume 2. (Translation), 2nd print, 2010.

6. Imenshahidi, M., Moallem, S.A., Tafaghodi, M., Rezaei, Ramin, Firouzi, Zohreh, 2011. Nonprescription Drug Therapy. MUMS press, Mashhad. (Translation)

7. Afrasiabi, H., Tafaghodi, M., Sajadi, S.A., Sadeghi, F., Fazly, B.S., 2013. Aulton’s Pharmacetics, the design and manufacture of medicines. Volume 1, MUMS Press, Mashhad. (Translation, 2015).

8. Afrasiabi, H., Tafaghodi, M., Sajadi, S.A., Sadeghi, F., Fazly, B.S., 2013. Aulton’s Pharmacetics, the design and manufacture of medicines. Volume 2, MUMS Press, Mashhad. (Translation, 2015).

 

Papers

1- Diwan, M., Tafaghodi, M., Samuel, J., 2002. Enhancement of immune responses by co-delivery of a CpG oligodeoxynucleotide and tetanus toxoid in biodegradable nanospheres. Journal of Controlled Release, 85, 247-262

2- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2002. Drug delivery from nasal route. Razi,, 155, 32-42.

3- Tafaghodi, M., Hasanzadeh, M., Rahimizadeh, M., 2003. Isolation and identification of Hyoscyamus insanus alkaloids. Iranian journal of Medicinal Plants, 2(7), 29-36.

4- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R.., 2004. Utilization of particulate and immuno-modulating adjuvants for enhancement of immune responses against tumors antigenic markers. Iranian Journal of Basic Medical Sciences, 6(4), 336-345.

5- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., Zakavi, S.R., Momen-nejad, M., 2004. Evaluation of the clearance characteristics of various microspheres in the human nose by gamma-scintigraphy. International Journal of Pharmaceutics, 280, 125-135.

6- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R.., 2004. Mucosal immunization. Razi, 175, 17-24.

7- Tafaghodi, M., Jaafari, M.R.., Sajadi Tabasi, S.A., 2004. Adjuvants. Razi, 174, 34-45.

8- Sajadi Tabasi, S.A., Tafaghodi, M., Jaafari, M.R., 2004. Dextran microspheres encapsulated with tetanus toxoid as a delivery system for nasal immunization: in vitro and in vivo characterization.  Iranian Journal of Basic Medical Sciences, 7(2), 88-98.

9- Jaafari, M.R., Tafaghodi, M., Sajadi Tabasi, S.A., 2005. Evaluation of the clearance characteristics of liposomes in the human nose by gamma-scintigraphy. Iranian Journal of Pharmaceutical Research, 4(1), 3-11.

10- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2006. Formulation and characterization and release studies of alginate microsphere encapsulated with tetanus toxoid. Journal of Biomaterials Science. Polymer Edition., 17(8), 909-924.

11- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2006. Induction of systemic and mucosal immune responses by intranasal administration of alginate microspheres encapsulated with tetanus toxoid and CpG-ODN. International Journal of Pharmaceutics, 319, 37-43.

12- Tafaghodi, M., Jaafari, M.R., Sajadi Tabasi, S.A., 2006. Nasal immunization studies by liposomes encapsulated with tetanus toxoid and CpG-ODN. European Journal of Pharmaceutics and Biopharmaceutics, 64, 138-145.

13- Tafaghodi, M., Jaafari, M.R., Nikouzadeh, A. 2007. Evaluation of systemic and mucosal immune responses following the nasal immunization by various sizes of liposomes encapsulated with tetanus toxoid. Iranian Journal of Basic Medical Sciences, 9, 4(32), 307-315.

14- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2007. Nasal immunization study by PLGA nanospheres encapsulated with tetanus toxoid and CpG-ODN. Iranian Journal of Pharmaceutical Research, 6(3), 151-158.

15- Ghiasi, Z., Sajadi Tabasi, S.A., Tafaghodi, M., 2007. Preparation and In Vitro  Characterization of Alginate Microspheres Encapsulated with Autoclaved Leishmania major (ALM) and CpG –ODN. Iranian Journal of Basic Medical Sciences, 10(2), 90-98.

16- Tafaghodi, M., Sajadi Tabasi, S.A., Payan, M., 2007. Alginate microspheres as delivery system and adjuvant for autoclaved Leishmania major (ALM) and Quillaja saponin (QS) - Preparation and characterization. Iranian Journal of Pharmaceutical Sciences, 3(2), 61-68.

17- Nazemian, F., Mohammad-Poor, A-H, Naghibi, M, Hasanzadeh-Khayat, M., Tafaghodi, M., Charkazi, S, Abrisham, S., 2007. The effect of pentoxiphylline on hemoglobin levels in patients with erythropoietin resistant anemia in hemodialysis patients. Nephrology Dialysis Transplantation, 22(Supplement 6), 355-355.

18- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2008. Nasal immunization studies by cationic, fusogenic and cationic-fusogenic liposomes encapsulated with tetanus toxoid. Current Drug Delivery, 5, 108-113.

19- Tafaghodi, M., Sajadi Tabasi, S.A., Kharazizadeh, M., 2008. Preparation and characterization of PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and Quillaja saponin. Saudi Pharmaceutical Journal, 16(1), 43-49.

20- Sajadi Tabasi, S.A., Tafaghodi, M., Jaafari, M.R., 2008. Induction of high antitoxin titers against tetanus toxoid in rabbits by intranasal immunization with dextran  microspheres. International Journal of Pharmaceutics, 360, 12-17.

21- Tafaghodi, M., Hadizadeh, F., Farahmand, F., 2008. Comparison of spectrophotometry and spectroflourimetry methods in determination of encapsulation efficiencies of TT in microspheres and liposomes, Pharmaceutical Sciences, summer, 53-59.

22- Tafaghodi, M., Sajadi Tabasi, S.A., Amiri, N., 2008. PLGA nanospheres loaded with Autoclaved Leishmania Major (ALM) and CpG-ODN: Preparation and in vitro characterization. Iranian Journal of basic medical Sciences, 11(2), 112-119.

23- Deldar, K., Nazemi, E., Balali Mood, M., Emami, S.A., Mohammadpour, A.H., Tafaghodi, M., Afshari, R., 2008. Effect of Coriandrum sativum L. extract on lead excretion in 3-7 year old children, Journal of Birjand University of Medical Sciences, 15, 11-19.   

24- Amin, M.R., Jaafari, M.R., Tafaghodi, M., 2009. Nasal immunization studies in rabbits by anionic and chitosan coated liposomes encapsulated with tetanus toxoid as a model antigen. Colloids and Surfaces B. Biointerfaces, 74, 225-229.

25- Khadivzadeh, T., Samadi, S., Emami, A., Tafaghodi, M., Sanjar Moosavi, N., Behnam, H.R., 2010. The Effect of Hypericum Perforatum on the Wound Healing and Scar of Cesarean. Journal of Alternative and Complementary Medicine, 16(1), 113-117.

26- Tafaghodi, M., Rastegar, S., 2010. Preparation and in vivo study of dry powder microspheres for nasal immunization. Journal of Drug Targeting, 18(3), 235-242.

27- Emami, S.A., Fakhrjafary, M., Tafaghodi, M., Hassanzadeh, M.K., 2010. Chemical Composition and Antioxidant Activities of the Essential Oils of Different Parts of Cupressus arizonica Greene. Journal of Essential Oil Research, 22, 193-199.

28- Tafaghodi, M., Jaafari, M.R., Eskandari, M., Khamesipour, A., 2010. Immunization against leishmaniasis by PLGA nanospheres loaded with an experimental Autoclaved Leishmania major (ALM) and Quillaja saponins. Tropical Biomedicine, 27, 639-650.

29- Alipour, S., Montaseri, H., Tafaghodi, M., 2010. Preparation and characterization of paclitaxel loaded alginate microparticles for pulmonary delivery. Colloids and Surfaces B. Biointerfaces, 81, 521-529.

30- Mohaghegh, M., Tafaghodi, M., 2011. Dextran microspheres could enhance immune responses against PLGA nanospheres encapsulated with tetanus toxoid and Quillaja saponins after nasal immunization in rabbit. Pharmaceutical Development and Technology, 16, 36-43.

31- Tafaghodi, M., Khamesipour, A., Jaafari, M.R., 2011. Immunization against leishmaniasis by PLGA nanospheres encapsulated with Autoclaved Leishmania major (ALM) and CpG-ODN. Parasitology Research, 108, 1265-1273.

32- Tafaghodi, M., Eskandari, M., Khamesipour, A., Jaafari, M.R., 2011. Alginate microspheres encapsulated with Autoclaved Leishmania major (ALM) and CpG-ODN induced partial protection and enhanced immune response against murine model of leishmaniasis. Experimental Parasitology, 129, 107-114.

 33- Maleki, M., Karimi, G., Tafaghodi, M., Raftari, S., Nahidi, Y., 2012. Comparison of Intralesional 2% zinc sulfate and Glucantime injection in treatment of acute cutaneous Leishmaniasis. Indian Journal of Dermatology, 57, 118-122.

34- Tafaghodi, M., Eskandari, M., 2012. The mucosal adjuvant potential of cross-linked dextran microspheres (CDM) as dry powder. Iranian Journal of Basic Medical Sciences, 15, 873-879.

35- Moghadam Aryaee, F., Tafaghodi, M., 2012. Mucosal adjuvant potential of Quillaja saponins and cross-linked dextran microspheres, co-administered with liposomes encapsulated with tetanus toxoid. Iranian Journal of Pharmaceutical Research, 11(3), 723-732.

36- Khodaverdi, E., Tafaghodi, M., Ganji, F., Abnoos, K., Naghizadeh, H., 2012. In vitro insulin release from thermosensitive chitosan hydrogel.  AAPS PharmSciTech, 13, 460-466.

37- Tafaghodi, M., Saluja, V., Kersten, G.F.A., Kraan, H., Slütter, B., Amorij, J.-P., Jiskoot W., 2012. Hepatitis B surface antigen nanoparticles coated with chitosan and trimethyl chitosan: impact of formulation on physicochemical and immunological characteristics. Vaccine, 30, 5341-5348.

38- Moghimipour, E., Tafaghodi, M., Balouchi, A., Handali, S., 2013. Formulation and in vitro Evaluation of Topical Liposomal Gel of Triamcinolone Acetonide. Research Journal of Pharmaceutical, Biological and Chemical Sciences (RJPBCS), 4, 101-107.

39- Hosseinzadeh, H., Tafaghodi, M., Moosavi, M.J., Taghiabadi, E., 2013. Effect of Aqueous and Ethanolic Extracts of Nigella sativa Seeds on Milk Production in Rats. JAMS Journal of Acupuncture and Meridian Studies, 6, 18-23. 

40- Zarifpour, M., Hadizadeh, F., Iman, M., Tafaghodi, M., 2013. Preparation and characterization of trimethylchitosan (TMC) nanospheres encapsulated with tetanus toxoid. Pharmaceutical Sciences, 1(2), 13-18.

41- Dehghan, S., Tavassoti Kheiri, M., Tabatabaiean, M., Darzi, S., Tafaghodi, M., 2013. Dry-powder form of chitosan nanospheres containing infulenza virus and adjuvants for nasal immunization. Archives of Pharmacal Research, 36:981-992.

42- Ganji, F., Khodaverdi, E., Tafaghodi, M., Sadoogh, M., 2013. Effects of Formulation Properties on Sol-Gel Behavior of Chitosan/glycerolphosphate Hydrogel. Iranian Polymer Journal, 22:785-790.

43- Khodaverdi, E., Tafaghodi, M., Beizaei, S., Abnous, Kh., Alibolandi, M., and Hadizadeh, F., 2013. Preparation and Characterization of PLGA-PEG-PLGA nanospheres prepared with a new thermogelling method for Insulin Delivery. Journal of Chemical and Pharmaceutical Research, 5, 311-319.

44- Khameneh Bagheri, B., Momen-nejad, M., Tafaghodi, M., 2014. In vivo evaluation of mucoadhesive properties of nanoliposomal formulations upon coating with trimethylchitosan polymer. Nanomedicine Journal, 1(3), 147-154.

45- Mohammadpour, A.H., Nazemian, F., Hasanzadeh, M., Tafaghodi, M., Salari, P., Charkazi, S., Naghibi, M., Shamsara, J., 2014. Evaluation of the effect of pentoxifylline on erythropoietin-resistant anemia in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation, 25, 73-78.

46- Razavi Rohani, S.S., Abnous, K., Tafaghodi, M., 2014. Preparation and characterization of spray-dried powders intended for pulmonary delivery of Insulin with regard to the selection of excipients. International Journal of Pharmaceutics, 465, 464-478.

47- Tafaghodi, M., Kersten, G.F.A, Jiskoot, W., 2014. Nano-adjuvanted polio vaccine: Preparation and characterization of chitosan and trimethyl chitosan (TMC) nanoparticles loaded with inactivated polio virus and coated with sodium alginate. Nanomedicine Journal, 1(4), 220-228.

48- Hosseinzadeh, H., Tafaghodi, M., Abedzadeh, S., Taghiabadi, E., 2014. Effect of Aqueous and Ethanolic Extracts of Pimpinella anisum L. Seeds on Milk Production in Rats. Journal of Acupuncture and Meridian Studies, 7(4), 211-216.

49- Ghoochi Atashbeyk, D., Khameneh Bagheri, B., Tafaghodi, M., Fazly Bazzaz, B.S., 2014. Eradication of methicillin-resistant Staphylococcus aureus infection by nanoliposomes loaded with gentamicin and oleic acid. Pharmaceutical Biology, 52 (11), 1423-1428.

50- Mohajer, M., Khameneh, B., Tafaghodi, M., 2014. Preparation and characterization of PLGA nanospheres loaded with inactivated influenza virus, CpG-ODN and Quillaja saponin. 17, 722-726.

51- Khodaverdi, E., Heidari, Z., Sajadi Tabassi, S.A., Tafaghodi, M., Alibolandi, M., Mirzazadeh Tekie, F.S., Khameneh, B., Hadizadeh, F., 2014. Injectable supramolecular hydrogel from insulin-loaded triblock PCL-PEG-PCL copolymer and γ-cyclodextrin with sustained-release property. AAPS PharmSciTech, 16(1), 141-149.

52- Dehghan, S., Tafaghodi, M., Bolourieh, T., Mazaheri, V., Torabi, A., Abnous, KH., Tavassoti Kheiri, M., 2014. Nasal immunaization against influenza by chitosan nanospheres encapsulated with Influenza whole virus and adjuvants in dry-powder form. International Journal of Pharmaceutics, 475, 1-8.

53- Kazemi-Beydokhti, A., Zinali heris, S., Tafaghodi, M., Jaafari, M.R., Hatamipoor, M., 2014. Microwave functionalized single-walled carbon nanotube as nanocarrier for the delivery of anticancer drug cisplatin: in vitro and in vivo evaluation. Journal of Drug Delivery Science and Technology, 24(6), 572-578.

54- Moayedian, T., Mosaffa, F., Khameneh-Bagheri, B., Tafaghodi, M., 2015. Combined effects of PEGylation and particle size on uptake of PLGA particles by macrophage cells. Nanomedicine Journal, 2(4), 299-304.

55- Mehravaran, A., Jaafari, M.R., Jalali, S.A., Khamesipour, A., Tafaghodi, M., Hojatizade, M., Badiee, A., 2015. The role of surface charge of ISCOMATRIX nanoparticles on the type of immune response generated against Leishmaniasis in BALB/c mice. Nanomedicine Journal, 2(4), 249-260.

56- Montaseri, H., Alipour, S., Tafaghodi, M., 2015. Inhalable, large porous PLGA microparticles loaded with pcalitaxel: Preparation, in vitro and in vivo characterization. Journal of Microencapsulation, 32(7), 661-668.

57- Rady Raz, N., Akbarzadeh-T, M.R., Tafaghodi, M., 2015. Bio-inspired Nanonetworks for Targeted Cancer Drug Delivery. IEEE Transaction of Nanobiosience, 14(8), 894-906.

58- Mehravaran, A., Jaafari, M.R., Jalali, S.A., Khamesipour, A., Tafaghodi, M., Hojatizade, M., Badiee, A., 2015. The role of surface charge of ISCOMATRIX nanoparticles on the type of immune response generated against Leishmaniasis in BALB/c mice. Nanomedicine Journal 2 (4), 249-260.

59- Mehravaran, A., Jaafari, M.R., Jalali, S.A., Khamesipour, A., Tafaghodi, M., Hojatizade, M., Abbasi, A., Badiee, A., 2015. Cationic Immune Stimulating Complexes Containing Soluble Leishmania Antigens: Preparation, Characterization and in Vivo Immune Response Evaluation. Iranian Journal of Immunology 12 (4), 274.

60- Radvar, M., Moeintaghavi, A., Tafaghodi, M., Ghanbari, H., Fatemi, H., Mokhtari, M.R., Najafi, F., Hoseinipour, Z., Dastmalchi, P., Farazi, F., 2016. Clinical efficacy of herbal mouth wash composed of Salix alba, Malva sylvestris and Althaea officinalis in chronic periodontitis patients. Journal of Herbal Medicine, 6, 24-27.

61- Shiehzadeh, F., Tafaghodi, M., 2016. Dry powder form of polymeric nanoparticles for pulmonary drug delivery. Current Pharmaceutical Design, 22(17), 2549-2560.

62- Amirnasr, M., Fallah-tafti, T., Sankian, M., Rezaei, A., Tafaghodi, M., 2016. Immunization against HTLV-1 with CHT and TMC nanoparticles loaded with recombinant env23 and env13 antigens of envelope protein gp46. Microbial Pathogenesis, 97, 38-44.

63- Alipour, S., Montaseri, H., Nekouian, A.A., Khalili Azad, A., Mohamadpour, A.H., Tafaghodi, M., 2016. Non-invasive endotracheal delivery of paclitaxel loaded alginate microparticles: pharmacokinetic study. Journal of Chemotherapy (In Press).

64- Tafaghodi, M., Jaafari, M-R. Eskandari, M., Khamesipour, A., 2016. Immunization against cutaneous leishmaniasis by Alginate microspheres loaded with Autoclaved Leishmania major (ALM) and Quillaja saponins. Iranian Journal of Pharmaceutical Research (In Press).

65- Hadizadeh, F., Khodaverdi, E., Javan, M., Tafaghodi, M., Sajadi Tabassi, S.A., Chamani, J., Khameneh, B., Mirzazadeh Tekie, F.S., 2016. Sustained Drug Delivery System for Insulin using Supramolecular Hydrogels Composed of Tri-block Copolymers. Submitted to IJPR.

66- Amini, Y., Moradi, B., Tafaghodi, M., Meshkat, Z., Ghazvini, K., Fasihi-Ramandi, M., 2016. TB trifusion antigen adsorbed on calcium phosphate nanoparticles stimulated strong cellular immunity in mice. Submitted to experimental nanoscience.

67- Karimi, S.M., Sankian, M., Khademi, F., Tafaghodi, M., 2016. Chitosan (CHT) and trimethylchitosan (TMC) nanoparticles as adjuvant/delivery system for parenteral and nasal immunization against Mycobacterium tuberculosis (MTb) ESAT-6 antigen. Submitted to Microbiology and Immunology.

68- Pirouzmand, H., Khameneh, B., Tafaghodi, M., 2016. Evaluation of immunoadjuvant potential of dry powder form of cross-linked dextran microspheres (CDM) mixed with chitosan ‎nanospheres encapsulated with tetanus toxoid, after nasal ‎immunization in rabbits. Submitted to Pharmaceutical Biology.

69- Amini, Y., Tafaghodi, M., Amel Jamehdar, S., Meshkat, Z., Moradi, B., Sankian, M., 2016. Heterologous expression, purification and characterization of the HspX, Ppe44 and EsxV proteins of Mycobacterium tuberculosis as a vaccine candidate in prokaryotic system. Submitted to Asian Pacific Journal of Tropical Medicine.

70- Dehghan, S., Kheiri, M.T., … , Tafaghodi, M., 2016. Dry powder vaccine preparation, characterization and immunogenic evaluation of Alginate-based whole inactivated influenza nasal vaccine in rabbits. Submitted to journal of Colloids and Surfaces B.

71- Mosafer, J., Abnous, Kh., Tafaghodi, M., Ramezani, M., 2016. In vitro and in vivo evaluation of anti-nucleolin-targeted magnetic PLGA nanoparticles loaded with doxorubicin as a theranostic agent for enhanced targeted cancer imaging and therapy. Submitted to Applied surface Science.

 

 

 

 

 

 

 

 

 

 

Presentations

1- Tafaghodi, M. Shokouhi Nejad, H., 1995. Evaluation of different methods of determination of poor soluble substances. Proceeding of the 2nd congress of Iranian pharmacy students, Mashhad, Iran.

2- Moghimipour E., Dehghan G. and Tafaghodi M., 1998. The study of HPMC concentrations on physical properties of coated tablets. Proceeding of the 6th Iranian Congress of Pharmaceutical Sciences, Tehran, Iran.

3- Tafaghodi M., Rahimizadeh M., Hassanzadeh M., 2000. Isolation and characterization of alkaloids of Hyoscyamus insanus. Proceeding of the 7th Iranian Congress of Pharmaceutical Sciences, Mashhad, Iran.

4- Tafaghodi, M., Jaafari, M.R., Sajadi Tabasi, S.A., 2000. Formulation and characterization of liposomes containing tetanus toxoid. Proceeding of the 7th Iranian Congress of Pharmaceutical Sciences, Mashhad, Iran.

5- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2002. Preparation and characterization of alginate microspheres encapsulated with tetanus toxoid for nasal delivery. Proceeding of the 8th Iranian Congress of Pharmaceutical Sciences, Shiraz, Iran.

6- Tafaghodi, M., Diwan, M., Samuel, J., Jaafari, M.R., Sajadi Tabasi, S.A., 2002. Increasing the immune responses by co-delivery of tetanus toxoid and CpG ODN encapsulated in PLGA nanospheres­. Proceeding of the 8th Iranian Congress of Pharmaceutical Sciences, Shiraz, Iran.

7- Tafaghodi, M., Zakavi, S.R., Sajadi Tabasi, S.A., Jaafari, M.R., Momen Nejad, H., 2002. Gamma-Scintigraphy as a novel method to study the distribution and clearance rate of different mucoadhesive nasal delivery systems. Proceeding of the 6th Annual Meeting of Nuclear Medicine, Mashhad, Iran.

8- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R.., 2003. Nasal immunization using alginate microspheres encapsulated with tetanus toxoid (TT). Proceeding of the 1st Congress of New Drug Delivery Systems, Tehran, Iran.

9- Sajadi Tabasi, S.A., Tafaghodi, M., Jaafari, M.R.., 2003. Nasal immunization using cross-linked dextran microspheres encapsulated with tetanus toxoid (TT). Proceeding of the 1st Congress of New Drug Delivery Systems, Tehran, Iran.

10- Tafaghodi, M., Jaafari, M.R.., Sajadi Tabasi, S.A., 2003. Nasal immunization using neutral, cationic, fusogenic and cationic-fusogenic liposomes encapsulated with tetanus toxoid (TT). Proceeding of the 1st Congress of New Drug Delivery Systems, Tehran, Iran.........

11- Tafaghodi, M., Samuel, J., Diwan, M., Sajadi, S.A., Jaafari, M.R., 2003. Utilization of particulate and immunomodulating adjuvants for enhancement of immune response against tumors antigenic markers. Proceeding of the 3rd Congress of National Biotechnology, Mashhad, Iran.

12- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R.., 2006. Nasal immunization studies by alginate and cross-linked dextran microspheres and PLGA nanospheres encapsulated with tetanus toxoid (TT). Proceeding of the 10th Iranian Congress of Pharmaceutical Sciences, Tehran, Iran.

13- Tafaghodi, M., Sajadi Tabasi, S.A., Kharazizadeh, M., 2007. Preparation and characterization of PLGA nonospheres encapsulated with autoclaved Leishmania major (ALM) and saponin adjuvant. Proceeding of the 3rd Congress of New Drug Delivery Systems, Tehran, Iran.

14- Tafaghodi, M., Hadizadeh, H., Farahmand, F., 2007. Determination of encapsulation efficiency of fluorescent tetanus toxoid in microsphere and Liposome drug delivery systems by spectrofluorimetery method. Proceeding of the 3rd Congress of New Drug Delivery Systems, Tehran, Iran.

15- Tafaghodi, M., Jaafari, M.R., Amin, M.R., 2007. Nasal Immunization Studies in Rabbits by Anionic and Chitosan Coated Liposomes Encapsulated with Tetanus Toxoid as a Model Antigen. Proceeding of the 1st Vaccine Congress, Amsterdam, Netherland.

16- Tafaghodi, M., Jaafari, M.R., Sajadi Tabasi, S.A., 2008. Preparation, characterization and immunization studies with PLGA nonospheres encapsulated with autoclaved Leishmania major (ALM) and saponin adjuvant. Proceeding of the 11th Iranian Congress of Pharmaceutical Sciences, Kerman, Iran.

17- Tafaghodi, M., 2009. Nanoparticulate drug delivery systems as vaccine adjuvant and delivery system. Proceeding of the Nanodrugs, nano-biotechnology, nano-biosensors and nano-materials in medical sciences. Mashhad, Iran.

18- Tafaghodi, M., Jaafari, M.R., Sajadi, S.A., Khamesipour, A., Amiri, N., 2009. Immunization against leishmaniasis by PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN. ICRC 2009, Zanjan, Iran.

19- Tafaghodi, M., Mohaghegh, M., 2009. Dextran microspheres could enhance immune responses against PLGA nanospheres encapsulated with tetanus toxoid and Quillaja saponins after nasal immunization in rabbit. ICRC 2009, Zanjan, Iran. 

20- Tafaghodi, M., Jaafari, M.R., Sajadi Tabasi, S.A., 2009. Induction of immune responses against leishmaniasis by alginate microspheres encapsulated with autoclaved Leishmania major (ALM) antigen and CpG-ODN.  Proceeding of the 3rd Modern vaccine adjuvant and delivery systems, Vienna, Austeria.

21- Tafaghodi, M., Jiskoot, W., Saluja, V., 2011. Hepatitis B surface antigen (HBsAg) nanoparticles coated with chitosan and trimethyl chitosan (TMC): impact of formulation on physicochemical and immunological characteristics.

 

22- Tafaghodi, M., 2016. Polymer based nanoparticles as adjuvant/vaccine delivery system for systemic and mucosal immunizations. 13th International Congress of Immunology and allergy of Iran. Tabriz, Iran.

 

 

 

 

 

 

 

 

 

 

Honors & Awards

Honored investigator (student) in medicinal sciences, Ferdowsi Festival, Mashhad, 2001 (Offered by MUMS and FUM).

Honored Pharmacist, Mashhad, 2002 (Offered by Khorasan Association of Pharmacists).

The best presentation in 8th Iranian Seminar of Pharmaceutical Scientists (Ph.D. student), Shiraz, 2002 (Offered by Iranian Association of Pharmaceutical Scientists).

Honored young researcher, 9th Iranian Seminar of Pharmaceutical Sciences, Tabriz, 2004 (Offered by Iranian Association of Pharmaceutical Scientists).

The best book translation (Adverse effects of herbal drugs vol. 1 and 2), Research week festival, Mashhad, 2004 (Offered by MUMS)

Three awards from Iranian Nanotechnology Initiative for supervision of two Pharm.D. thesis.

The best book translation (Pharmaceutics, vol. 1), Research week festival, Mashhad, 2006 (Offered by MUMS)

Honored lecturer, MOALEM week festival, Mashhad, 2007 (Offered by MUMS)

The best book translation (Pharmaceutics, vol. 2), Research week festival, Tehran, 2007 (Offered by University of Tehran)

The best book translation (Pharmaceutics, vol. 2), Research week festival, Mashhad, 2007 (Offered by MUMS)

The best presentation in ICRC 2011, Mashhad, 2011 (Offered by Iranian Controlled Release Society).

The best book translation (Nonprescription Drug Therapy), Research week festival, Mashhad, 2011 (Offered by MUMS)

The best book translation (Pharmaceutics, vol. 1), Research week festival, Mashhad, 2015 (Offered by MUMS).

 

 

 

 

 

Members                                                  hip Membership

Member of “Nanotechnology Research Center”, Mashhad University of Medical Sciences

Member of “Pharmaceutical Research Center”, Mashhad University of Medical Sciences

Member of “Controlled Release Society of Iran”

Editorial member of Asian Pacific Journal of Tropical Medicine (2009-2011)

Editorial member of Nanomedicine Journal

Reviewer of Drug Development and Industrial Pharmacy journal

Reviewer of Journal of Drug Targeting

Reviewer of Journal of Microencapsulation

Reviewer of Journal of the Taiwan Institute of Chemical Engineers

Reviewer of Iranian Journal of Pharmaceutical Research

Reviewer of Iranian Journal of Basic Medical Sciences

Reviewer of DARU journal

Reviewer of Colloids and Surfaces, B journal

 

 

 

Administrative Responsibilities

 

 

 

 

 

 

Other Skills

 

 

 

 

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Dr Amir Hooshang Mohammadpour

 

 

 

Professor of  Clinical Pharmacy

        [at]mums.ac.ir
[at]yahoo.com

 

Address: School of Pharmacy, Mashhad University of Medical Sciences

Tel: +98 5138823255

Fax: +98 5138823251

 

Mohamadpoorah@ mums.ac.ir

This email address is being protected from spambots. You need JavaScript enabled to view it.

Updated at:                           

                                                       und Educational Background 

1999  Pharm D, School of Pharmacy, Ahvaz University of Medical Sciences, Iran

 

2004  Board Certified Clinical Pharmacy ,School of Pharmacy, Tehran University of Medical Sciences, Iran

 

2012-2013  Fellowship of Clinical Pharmacokinetic  , School of Pharmacy, University of Rhode Island, USA

 

                                                                   Research Interests

Clinical trials

 Clinical Pharmacokinetic

 Drug Use Evaluation

 

                                                                       Publications

1-     Seyedeh Pardis Jahanbakhsh, Ali Akhondpour Manteghi, Seyed Ahmad Emamic,Saman Mahyaria, Beheshteh Gholampourd, Amir Hooshang Mohammadpour,,Amir hossein Sahebkare. “ Evaluation of the efficacy of Withania somnifera (Ashwagandha) root extract in patients with obsessive-compulsive disorder: A randomized double-blind placebo-controlled trial.” Complementary Therapies in Medicine 27 (2016) 25–29

 

2-     Saman Mahyari , Behnam Mahyari , Seyed Ahmad Emami , Bizhan Malaekeh-Nikouei , Seyedeh Pardis Jahanbakhsh , Amirhossein Sahebkar ,Amir Hooshang Mohammadpour “ Evaluation of the efficacy of a polyherbal mouthwash containing Zingiber officinale, Rosmarinus officinalis and Calendula officinalis extracts in patients with gingivitis: A randomized double-blind placebo-controlled trial “  Complementary

 

Therapies in Clinical Practice 22 (2016) 93-98

 

3-      Mahmoud Hashemzaei, B. Saeed Keykha, C. Fatemeh Shahraki, D. Amir hooshang Mohammadpour and E. Kaveh Tabrizian” EFFECTS OF MAGNESIUM SULFATE ON THE ACQUISITION AND REINSTATEMENT OF MORPHINE-INDUCED CONDITIONED PLACE PREFERENCE IN MICE” J Fundam Appl Sci. 2016, 8(2S), 112-123

 

4-     Seyed Adel Moallem , Amir Hooshang Mohamadpour , Khalil Abnous , Mojtaba Sankian , Hamid Reza Sadeghnia , Aristidis Tsatsakis , Shabnam Shahsavan. “Erythropoietin in the treatment of carbon monoxide neurotoxicity in rat” Food and Chemical Toxicology 86 (2015) 56-64

 

5-     Mitra Asgharian Rezaee, Amir Hooshang Mohammadpour, Mohsen Imenshahidi,Mahmoud Mahmoudi, Mojtaba Sankian, Konstantinos Tsarouhas, Andreas Tsakalof,Aristidis Micheal Tsatsakis, Seyed Adel Moallem “Protective effect of erythropoietin on myocardial apoptosis in rats exposed to carbon monoxide ” Life Sciences 148 (2016) 118–124

6-     Tamara Aghebati, Ali Badiee, Amir Hooshang Mohammadpour, Mohammad Afshar, Mahmoud Reza Jaafari, Khalil Abnous, Sobhan Issazadeh, Saeed Hashemzadeh,Mohammad Zareh, Haydeh Hashemizadeh, Saeed Nazemig “Anti-atherosclerosis effect of different doses of CETP vaccine in rabbit model of atherosclerosis” Biomedicine & Pharmacotherapy ; 81 (2016) 468–473

 

7-    Hashemzaei M, Imen Shahidi M, Moallem SA, Abnous K, Ghorbani M, Mohamadpour AH“Modulation of JAK2, STAT3 and Akt1 proteins by granulocyte colony stimulating factor following carbon monoxide poisoning in male rat” Drug Chem Toxicol. 2016 Jan 25:1-5

 

8-     Maryam Ghorbani, Amir Hooshang Mohammadpour, Khalil Abnous, Ahmad Reza Movassaghi, Javad Raouf Sarshoori, Shabnam Shahsavand, Mahmoud Hashemzaei andSeyed Adel Moallem “G-CSF administration attenuates brain injury in rats following carbon monoxide poisoning via different mechanisms” Environ Toxicol. 2015 Oct 27. doi: 10.1002/tox.22210. [Epub ahead of print

 

 

9-       PARASTOO MIRZABEIGIA, AMIR HOOSHANG MOHAMMADPOURB, MOJTABA SALARIFARC, KHEIROLLAH GHOLAMIA, MOJTABA MOJTAHEDZADEHA AND MOHAMMAD REZA JAVADIA . “The Effect of Curcumin on some of Traditional andNon-traditional Cardiovascular Risk Factors: A Pilot Randomized, Double-blind, Placebo-controlled Trial” . Iranian Journal of Pharmaceutical Research (2015), 14 (2): 479-486

 

 

 

10-  ABOUBAKR RAHMANI, AMIR HOOSHANG MOHAMMADPOUR, ADELEH SAHEBNASAGH, SEYED AHMAD MOHAJERI”  Haloperidol imprinted polymer: preparation, evaluation, and application for drug assay in brain tissue” . Anal Bioanal Chem (2014) 406:7729–7739

 

11-  SEPIDEH ELYASIA, HOSSEIN KHALILIB*, SIMIN DASHTI-KHAVIDAKIB, HAMID EMADI-KOOCHAKC,AMIRHOOSHANG MOHAMMADPOURA AND ALIREZA ABDOLLAHID   “Elevated Vancomycin Trough Concentration:Increased Efficacy and/or Toxicity?” Iranian Journal of Pharmaceutical Research (2014), 13 (4): 1241-1247

 

12-  MARYAM VAHABZADEH , AMIR-HOUSHANG MOHAMMADPOUR “Effect of Diabetes Mellitus on the Metabolism of Drugs and Toxins” J Clin Toxicol 2015, 5:2

 

 

13-  Ali Gholamzadeh; Sara Amini ; Amir Hooshang Mohammadpour;Maryam Vahabzadeh; Amir Farjam Fazelifar; Afsoon Fazlinezhad; Mashalla Dehghani; Mohsen Moohebati; Mostafa Dastani; Bizhan Malaekeh- Nikouie, ; Homa Falsoleiman“Erythropoietin reduces post-PCI arrhythmias in patients with ST elevation myocardial infarction” Journal of Cardiovascular Pharmacology , 65(6):555-561

 

 

14-  Amir Hooshang Mohamadpour,a Leila Abdolrahmani,a Hamed Mirzaei,b Amirhosein Sahebkar,c Mohsen Moohebati,d Maryam Ghorbani,e Gordon A. Ferns,f and Majid Ghayour-Mobarhan “Serum Osteopontin Concentrations in Relation to Coronary Artery Disease”Archive Medical Research, 46 (2015) : 112 – 117

 

15-   Maryam Amirchaghmaghi • Zahra Delavarian1 • Mehrdad Iranshahi2 • Mohammad Taghi Shakeri • Pegah Mosannen Mozafari • Amir Hushang Mohammadpour • Fatemeh Farazi • Milad Iranshahy.” A Randomized Placebo-controlled Double Blind Clinical Trial of Quercetin for Treatment of Oral Lichen Planus” .  Journal of Dental Research, Dental Clinics, Dental Prospects(2015) : 9 (1)

 

 

16-Mahmoudi L , Mohammadpour AH , Niknam R , Ahmadi A , Mojtahedzdeh M . Limited sampling strategy for estimation of amikacin optimal sampling time in critically ill adultsAnaesthesia and Intensive Care , 2014; 42(2):228-233Find all citations by this author (default).Or filter your current search Find all citations by this author (default).Or filter your current search

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  17- Mohammad Moshiri, Amir Hooshang Mohammadpour, Maryam Vahabzadeh,

Leila Etemad, Bahram Memar, and Hossein Hosseinzadeh. Evaluating the Effects and Safety of Intravenous Lipid Emulsion on Haloperidol-Induced Neurotoxicity in Rabbit.2014; 108 : 44-47

 

21-.Milad Iranshahi, Amir Hooshang Mohammadpoor, Mohammad Hassanzadeh Khayyat, Mehrdad Iranshahi. Method validation for the one month stability study of trans resveraterol in human plasma. Jundishapour J Nat Pharm Prod, 2013; 8(2); 65-9

 

22-.Maryam Ghorbani , Amir Hooshang Mohamadpour , Soghra Mehri ,Khalil Abnous , Mohammad Hassanzadeh-Khayyat.  Proteomics screening of molecular targets of granulocyte colony stimulating factor in the mouse brain and PC12 cell line. Life Sciences. 2014 In Press

 

23-. Leila Etemad , Afshar Mohammad , Amir Hooshang Mohammadpour , Nasser Vahdati Mashhadi , Seyed Adel Moallem . Teratogenic Effects of Pregabalin in Mice. Iran J Basic Med Sci. 2013; 16: 1065-1070

 

24-.Mohammadpour AH, Akhlaghi F. Future of Cholesteryl Ester Transfer Protein (CETP) Inhibitors: A Pharmacological Perspective. Clin Pharmacokinet. 2013 52(8):615-626

25-Moshiri M1, Vahabzadeh M, Mohammadpour AH, Hosseinzadeh H.  Evaluation of intravenous lipid emulsion on haloperidol-induced hypotension in rabbits. Toxicol Ind Health. 2014 Jan 20. [Epub ahead of print]

26-Mohammadpour AH, Nazemian F1, Khaiat MH, Tafaghodi M, Salari P, Charkazi S, Naghibi M, Shamsara J.  Evaluation of the effect of pentoxifylline on erythropoietin-resistant anemia in hemodialysis patients. Saudi J Kidney Dis Transpl. 2014 Jan;25(1):73-8.

27-.Maryam Vahabzadeh, Mohammad Moshiri,  Amir Hooshang Mohammadpour, and Hossein Hosseinzadeh,  Promising Effects of Intravenous Lipid Emulsion as an Antidote in Acute Tramadol Poisoning. Regional Anesthesia and Pain Medicine, 2013; 38(5): 425-30

28-Amir Hooshang Mohammadpour, Homa Falsoleiman, Jamal Shamsara, Ghazaleh Allah Abadi, Ramin Rasooli ,Mohammad Ramezani .Pentoxifylline Decreases Serum Level of Adhesion Molecules in Atherosclerosis Patients. Iranian Biomedical Journal. Iran Biomed J. Jan 2014; 18(1): 23–27

29-.Amir Hooshang Mohammadpour, Fatemeh Nazemian, Jamal Shamsara, Maryam Bafandegan, Maryam Ghorbani1 and Seyed Adel Moallem . Effects of omega-3 administration on concentration of serum inflammatory makers in renal transplant recipient .African Journal of  Pharmacy and Pharmacology.  2013; 7 (29): 2021-2024

30-. Amir Hooshang Mohammadpour, Mohammad Ramezani, Nasim Tavakoli Anaraki, Bizhan Malaekeh-Nikouei, Sara Amel Farzad, and Hossein Hosseinzadeh.Development and Validation of HPLC Method for Determination of Crocetin, a constituent of Saffron, in Human Serum Samples. Iran J Basic Med Sci. 2013 January; 16(1): 47–55

31-.Maryam M Ghorbani, Seyyed Adel S Moallem, Khalil K Abnous, Seyyed Abbas SA Tabatabaee Yazdi, Ahmad Reza AR Movassaghi, Mohammad M Azizzadeh, Amir Hooshang AH Mohamadpour* Drug Chem Toxicol 36(1):102-8 (2013), The effect of granulocyte colony-stimulating factor administration on carbon monoxide neurotoxicity in rats. Drug Chem Toxicol.2013; 36(1):102-8

32-.Mahmoudi L, Mohammadpour AH, Ahmadi A, Niknam R, Mojtahedzadeh M. Influence of sepsis on higher daily dose of amikacin pharmacokinetics in critically ill patients Eur Rev Med Pharmacol Sci. 2013 Feb;17(3):285-91.

33-AH Mohamadpour, Z Ayati, MR Parizadeh, O Rajbai, H Hosseinzadeh . Safety Evaluation of Crocin (a constituent of saffron) Tablets in Healthy Volunteers
Iranian journal of basic medical sciences. 2013; 16 (1), 39-46

34-.G Kamalinia, S Brand, P Ghaeli, N Abedi, H Bajoghli, V Sharifi, A Zahiroddin , AH Mohammadpour . Serum Levels of Sodium Valproate in Patients Suffering from Bipolar Disorders: Comparing Acute and Maintenance Phases of Mania
Pharmacopsychiatry. 2013;46(3):83-7

35-AH Mohammadpour, SA Moallem, M Bafandegan, J Shamsara, F Nazemian. Effects of omega-3 administration on homocysteine serum concentration in renal transplant recipient ,Journal of Pharmaceutical Care .2013;1 (1), 25-28

36-25.M Hassanzadeh Bashtian, SA Emami, N Mousavifar, HA Esmaily, M Mahmoudi, AH Mohammadpour Evaluation of Fenugreek Effects (Trigonella foenum-graceum L.) Seeds Extract on Insulin Resistance in Women with Polycystic Ovarian Syndrome . Iranian Journal of Pharmaceutical Research. 2013;12(2):475-481

37-Vahid Jomezadeh, Amir Hooshang Mohammadpour,Omid Rajabi, Alireza Tavassoli, Ghodratolah MaddahEvaluation of Curcumin Effects on Post-Operative Peritoneal Adhesion in Rats. Iran J Basic Med Sci. 2012 Nov-Dec; 15(6): 1162–1167.

38-Shabnam Shahsavand, Amir Hooshang Mohammadpour, Ramin Rezaee, Effat Behravan, Ramin Sakhtianchi,and Seyed Adel Moallem. Effect of Erythropoietin on Serum Brain-derived Biomarkers after Carbon Monoxide Poisoning in Rats. Iran J Basic Med Sci. 2012 Mar-Apr; 15(2): 752–758.

39-Shamsara J,Mohammadpour AH, Behravan J,Falsoleiman H,Ramezani M.”Pentoxifylline decreases soluble CD40 ligand concentration and CD40 gene expression in coronary artery disease patients”Immunopharmacol Immunotoxicol. 2012;34(3)523-9

40-Elyasi S,Khalili H,Dashti-Khavidaki S,Mohammadpour A.”Vancomycin-induced nephrotoxicity:mechanism,incidence,risk factors and special populations.A literature review”.Eur J Clin Pharmacol. 2012 Sep;68(9):1243-55

41-Amir Hooshang Mohammadpour,Jamal Shamsara,Saeed Nazemi,Samira Ghadirzadeh,Shabnam Shahsavand and Mohammad Ramezani.”Evaluation of RANKL/OPG serum concentration ratio as a new biomarker for coronary artery calcification:a pilot study.” Thrombosis. 2012; Epub 2012 Mar 28

42-Mohammad Reza Khakzad,Majid Mirsadraee,Amirhooshang Mohammadpour,Kamran Ghafarzadegan,Raziye Hadi,Mahdiye Saghari,Mojtaba Meshkat.”Effect of verapamil on bronchial goblet cells of asthma: an experimental study on sensitized animals” Pulmonary Pharmacology & Therapeutics.(2012);25:163-168.

43-Amir Hooshang Mohammadpour,Saeed Nazemi,Maryam Foroughi,Maryam Ghorbani,Jamal Shamsara and Javad Behravan.” Evaluation of the association between AT 1 R1166C polymorphism and the incidence of CAD and CAC score in Iranian population ”.Arch.Biol.Sci,Belgrade,2012;64(2),401-407

44-Jamal Shamsara, Javad Behravan, Homa Falsoleiman, Amir Houshang Mohammadpour, Mohammad Ramezani. The effects of pentoxifylline administration on NFΚB P50 transcription factor expression. ARYA A therosclorosis. 2012;7 (4):133-137

45-.Aghebati T, Foroughipour M, Azarpazhooh MR, Mokhber N, Hasanzadeh Khayat M, Vahdati N, Mohammadpour AH*. Relationship between Patient Demographic Characteristics, Valproic Acid Dosage and Clearance in Adult Iranian Patients. Iran J Basic Med Sci. 2012 Mar;15(2):702-8

46-.Mitra Asgharian Rezaeea, Seyed Adel Moallem, Mohsen Imenshahidi, Mahdi Farzadniac and Amir Hooshang Mohammadpour*Effects of Erythropoietin on Electrocardiogram Changes in Carbon Monoxide Poisoning: an Experimental Study in Rats.  Iranian Journal of Pharmaceutical Research .2012; 11 (4): 1191-1199

47-S Lotfi Noghabi, A Vahidian Kamyad, M Foroughipour, AH Mohammadpour Estimating the Optimal Dosage of Sodium Valproate in Idiopathic Generalized Epilepsy with Adaptive Neuro-Fuzzy Inference System. Basic and Clinical Neuroscience .2012;3 (3): 24-31

48-Jamal Shamsara,Javad Behravan,Homa Falsoleiman,Amir Hooshang Mohammadpour,Joerg Renderis,Mohammad Ramezani.Pentoxifylline administration changes protein expression profile of coronary artery disease patients. 2011 Nov 1;487(1):107-11

49-Amir Hooshang Mohammadpour, Fatemeh Nazemian, Reza K, Reza Kouhrokhi,Mohammad Ramezani , Jamal Shamsara “Effect Of Omega-3 Fatty Acids On Plasma Level Of 8-Isoprostane In Kidney Transplant Patients” Journal of Renal Nutrition , 2011; 21(2): 196-199

 

50-Amir Hooshang Mohammadpour,Fatemeh Nazemian,Seyed Adel Moallem,Seyed Ali Alamdaran,Elham Asad-Abadi,Jamal Shamsara. Correlation between Heat-Shock Protein 27 serum concentration and common carotid intima-media thickness in hemodialysis patients.Iranian Journal of Kidney Diseases.2011; 5:260-6 2011.

51-Mohamadpour AH, Moallem SA, Hashemzaei M, Abnous K, Tabatabaee Yazdi SA, Imenshahidi M.” Effects of granulocyte colony-stimulating factor on electrocardiogram changes after carbon monoxide poisoning in rats” Drug Chem Toxicol. 2012 ; 35(4),353-360.

52-Amir Hooshang Mohammadpour,Mohsen Foroughipour, Mahmoud Reza Azarpazhooh, Mohammad Hasanzadeh Khayat,Saeed Rezaee,Tamara Aghebati,Jamal Shamsara. Comparison of valporic acid clearance between epileptic patients and patients with acute mania.Iranian journal of basic medical sciences. 2011;14(6): 546-550

53-.Niloufar Mohammadpour, Sepideh Elyasi,Naser vahdati,Amir Hooshang Mohammadpour*,Jamal Shamsara.A review on therapeutic drug monitoring of Immunosuppressant drugs. Iranian journal of basic medical sciences, 2011; 14(6), 485-498

54-Seyed adel Moallem, Fatemeh Nazemian , Sepideh Eliasi ,Seyed Ali Alamdaran, Jamal Shamsara, Amir Hooshang Mohammadpour* “Correlation between CathepsinD serum concentration and carotid intima media thickness in hemodialysis patients” Int Urol Nephrol 2011 Sep;43(3):841-8

55-.Mehdi Bakhshaee, Farahzad Jabbari, Saeed Hoseini, Reza Farid, Mohammad Hadi Sadeghian, Mohsen Rajati, Amir Houshang Mohamadpoor, Rahman Movahhed, and Mohammad Ali Zamani. Effect of Silymarin in the Treatment of Allergic Rhinitis. Otolaryngology–Head and Neck Surgery. 2011;145(6) :904–909

56-N.Moosavifar,AH Mohammadpour,M Jallali,G karimi and H saberi.Evaluation of effect of silymarin on granulose cell apoptosis and follicular development in patients undergoing in vitro fertilization.Eastern meditererranean Health Journal.2010; 16(6):642-45.

57- Afshar M, Moallem SA, Houshang Mohammadpour A, Shiravi A, Majid Jalalian S, Jafar Golalipour M.” Teratogenic effects of carbamazepine on embryonic eye development in pregnant mice” Cutan Ocul Toxicol. 2010 Mar;29(1):10-15

58-Amir Hooshang Mohammadpour, Fatemeh Nazemian, Gholamreza Karimi, Mahdi Moatamedi, Somayeh Charkazi, Jamal Shamsara . “ Effect of Silymarin Administration on TNF-α serum concentration in peritoneal dialysis” Phytotherapy Research, 2010; 24: 1654-1657

59-Foroughipour M, Mohammadpour AH*, Azarpajooh MR, Mokhber N, Hasanzadeh Khaiat M, Rezaee S, Aghebati T, Vahdati N, Shamsara J “Therapeutic Drug Monitoring of valproic acid in patients with monotherapy at steady state”: Iranian Journal of Basic Medical science. 2009;12(3):146-149

 

60-Bazzaz BS, Naderinasab M, Mohamadpoor AH, Farshadzadeh Z, Ahmadi S, Yousefi F. The prevalence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae among clinical isolates from a general hospital in Iran. Acta Microbiol Immunol Hung. 2009 Mar;56(1):89-99.

 

61-.J Shamsara, M Ramezani, AH Mohammadpoor*Why homocysteine-lowering therapy does not have beneficial effects on patients with cardiovascular disease?
Bioscience Hypotheses .2009 ;2 (1):13-15

62-Amir Hooshang Mohammadpur, Fatemeh Nazemian, Bahareh Abtahi, Massih Naghibi “Influence of renal graft function on mycophenolic acid pharmacokinetics during the period after kidney transplant”. Experimental and Clinical Transplantation. 2008; 4:276-281

63-Mohammadpour AH, Nazemian F, Abtahi B, Naghibi M, Rezaee S, Rajzbi O “ Estimation of abbreviated Mycophenolic acid area under the concentration time curve during post transplant period by limited sampling strategy” Transplantation Proceeding . 2008,;40:3668-3672 

64-Mohammad Pour AH, Nazemian F, Hassanzadeh Khayat M, Bahrami A.A., Kazemi M. “Effect of Gancyclovir on Pharmacokinetics of Mycophenolate Mofetil in Kidney Transplant Patients” Iranian Journal of Basic Medical Sciences. 2008; 10 (4): 233-238

65-Nazemian F, Mohammadpur AH*, Abtahi B, Naghibi M “Pharmacokinetics of mycophenolic acid during the early period after renal transplant: Exprimental and clinical transplantation. 2007; 5 (2): 658-63

66-M Abbasi Nazari, AH Mohammadpour, J Behjati ardakani, , MR Rouini, KH Gholami The effect  of atenolol on thyroid hormons  in subclinical  hyperthyroidism , Iranian Journal of Pharmaceutical Sciences. 2005;1(4): 243-248

67-Mohammadpoor AH, sadraee S, Ghaeli P, foroughipoor M, Noroozian M, Rezaee S. Comparison of carbamazepin clearance between epileptic patients and paitents with acute Mania, DARU, 2004; 12 (4): 141-144

 

                                                                      Presentations

 

 

 

 

 

 

 

 

 

 

                                                                    Honors & Awards

 

2011  Outstanding Scientist Award, Mashhad University of Medical Sciences

 

2016 Outstanding Educational Award, Mashhad University of Medical Sciences

 

 

 

Membership

 

Rational Use of Drugs Council, Mashhad University of Medical Sciences, Mashhad, Iran

 

Ethic committee  Research Council, Mashhad University of Medical Sciences, Mashhad, Iran

 

 

                                                           Administrative Responsibilities

 

2006-2012 Chair of Department of Pharmacodinamy and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

 

2009-2011 , vice chancellor for research, School of Pharmacy, Mashhad University of Medical

Sciences, Mashhad, Iran

 

2013 -2016 Chair of Department of Clinical Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

 

 

 

 

Other Skills

 

 

 

 

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Dr. Gholamreza Karimi

 

 

 

Professor of Pharmacology and Toxicology

 

        [at]mums.ac.ir
[at]yahoo.com

 

Address:

Tel:

Fax

 

karimig [at]mums.ac.ir

……….[at]yahoo.com

Updated at:                           

                                                       und Educational Background 

 

Cardiovascular pharmacology and toxicology

 

 

 

                                                                   Research Interests

 

Cardiovascular pharmacology and toxicology

 

 

 

                                                                       Publications

 

  1. Kobra Shirani, Faezeh Vahdati Hassani, Kamal Razavi Azar-Khiavi, Zohreh Samie Moghaddam and Gholamreza Karimi*. Determination of methanol in Iranian herbal distillates. J Complement Integr Med. 2016; aop
  2.  Nafiseh Sadat Alamolhodaei  ,Kobra Shirani  ,Gholamreza Karimi ,∗.Arsenic cardiotoxicity :An overview,Environmental Toxicology and Pharmacology 40(2015)1005–1014
  3. Maryam Rahnama, Mahmoud Mahmoudi, Shahrzad Zamani Taghizadeh Rabe, Mahdi Balali-Mood, Gholamreza Karimi, Nafiseh Tabasi, and Bamdad Riahi-Zanjani. Evaluation of anti-cancer and immunomodulatory effects of carnosol in a Balb/c WEHI-164 fibrosarcoma model. J Immunotoxicol, Volume 12, Issue 3, 1 July 2015, Pages 231-238. (IF:1.22)
  4.  Mahmoudi M, Zamani Taghizadeh Rabe S, Balali-Mood M, Karimi G, Memar B, Rahnama M, Tabasi N, Khazaee M, Riahi-Zanjani B. Immunotoxicity induced in mice by subacute exposure to berberine. J Immunotoxicol. Volume 13, Issue 2, 3 March 2016, Pages 255-262.  (IF:1.22)
  5. Hassani FV, Rezaee R, Sazegara H, Hashemzaei M, Shirani K, Karimi G. Effects of silymarin on neuropathic pain and formalin-induced nociception in mice. Iran J Basic Med Sci. 2015 Jul;18(7):715-20.
  6.  Bamdad Riahi-Zanjani, Mahdi Balali-Mood, Elaheh Mohammadi, Hassan Badie-Bostan, Bahram Memar, Gholamreza Karimi*. Safranal as a safe compound to mice immune system. AJP, Vol. 5, No. 5, Sep-Oct 2015. ISC 
  7.  Mahmoud Mahmoudi; Shahrzad Zamani Taghizadeh Rabe; Maryam Rahnama ; Mahdi Balali Mood; Gholamreza Karimi  ; Bamdad Riahi-Zanjani ,*. Use of Carnosol as a Highly Immunosuppressive Agent.  Jundishapur J Nat Pharm Prod. 2015 August; 10(3): e20824.  Pubmed
  8. Gholami, M.  ; Moallem, S.A.;  Afshar, M. ; Etemad, L. * ; Karimi, G. Maternal Exposure to  Silymarin  Leads to  Phatological Changes in mouse  Foetuses. Pharmacology online, Volume 2, 2015, Pages 38-43. Scopus
  9. Faezeh Vahdati Hassani   , Ramin Rezaee         , Hasan Sazegara , Mahmoud    Hashemzaei , Kobra  Shirani   , Gholamreza Karimi   * . Effects     of  silymarin   on           neuropathic  pain     and     formalin‐induced        nociception      in         mice. Iran J Basic Med Sci, Vol. 18, No. 7, Jul 2015 .ISI
  10. Amir  Hooshang  Mohammadpour, Alireza  Tavassoli, Mohammad  Reza  Khakzad,  Elahe  Zibaee, Mohammad ,AfsharMahmoud Hashemzaei , Gholamreza Karimi*. Effect of gold nanoparticles on  postoperative peritoneal adhesions in rats. Nanomed J, Vol. 2, No. 3, Summer 2015.ISC 
  11. Kobra Shirani a ,Faezeh Vahdati Hassani a ,Kamal Razavi-Azarkhiavi a ,Somayeh Heidari a ,Bamdad Riahi Zanjani b ,Gholamreza Karimi c,∗ Phytotrapy of cyclophosphamide-induced immunosuppression.  Enviromental toxicology  and pharmacology . 2015 May;39(3):1262-1275. IF:2.084
  12. Mahmoud Mahmoudi, Shahrzad Zamani Taghizadeh Rabe, Mahdi Balali-Mood, Gholamreza Karimi , Nafiseh Tabasi and Bamdad Riahi-Zanjani* . Ursolic acid induced apoptotic cell death following activation of caspases in isolated human melanoma cells. Cell Biol Int,39(2015) 230–236. IF:1.933 
  13.  Parisa Mirhoseini Moosavi, Ali Reza Astaraei ,Alireza Karimi, Mohammad Moshiri, Leila Etemad, Majid Zeinalid, Gholamreza Karimi. Efficacy of orally administered montmorillonite for acute iron poisoning detoxification in rat. Applied Clay Science 103 (2015) 62–66. IF:2.467
  14. Ramin Rezaee, Khadijeh Jamialahmadi , Bamdad Riahi Zanjani, Mahmoud Mahmoudi .Crocin Effects on Human Myeloma Cells Regarding Intracellular Redox State, DNA Fragmentation, and Apoptosis or Necrosis Profile. Jundishapur J Nat Pharm Prod. 2014 November; 9(4). Pubmed
  15. Bamdad Riahi-Zanjani, Mahdi Balali-Mood, Seyed-Reza Mousavi, Gholamreza Karimi, Mahmood Sadeghia, Elham Shirmast, Mahmoud Mahmoudi. Serum cytokine profiles of Khorasan veterans 23 years after sulfur mustard exposure. Cytokine. 2014 Dec;70(2):161-4.
  16. Kobra Shirani, Javad Behravan, Fatemeh Mosaffa, Mehrdad Iranshahi, Babak  Mehmankhah, Kamal Razavi-Azarkhiavi, Karimi, G*,.Evaluating the effects of galbanic acid on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes. AJP, Vol. 4, No. 5, Sep-Oct 2014

 

  1. R.   Jabini . R.   Jaafari . F.   Vahdati Hasani .F.   Ghazizadeh .A.   Khamesipour , G.   Karimi

Effects of Combined Therapy with Silymarin and Glucantime on Leishmaniasis Induced by Leishmania  major in BALB/c Mice. Drug Res. 2014 Mar 12

  1. Adeleh Sahebnasagh , Karimi, G*, Seyed Ahmad Mohajeri.  Preparation and Evaluation of Histamine Imprinted Polymer as a Selective Sorbent in Molecularly Imprinted Solid-Phase Extraction Coupled with High Performance Liquid Chromatography Analysis in Canned Fish. Food Anal. Methods (2014) 7:1–8. (IF:1.969)
  2. Maryam Rahnama, Mahmoud Mahmoudi, Shahrzad Zamani Taghizadeh Rabe, Mahdi Balali-Mood, Gholamreza Karimi, Nafiseh Tabasi and Bamdad Riahi-Zanjani. Evaluation of anti-cancer and immunomodulatory effects of carnosol in a Balb/c WEHI-164 fibrosarcoma model. J Immunotoxicol, Volume 12, Issue 3, 1 July 2015, Pages 231-238
  3.  Khadijeh Jamialahmadia,, Omid Arastehc, Maryam Matbou Riahi, Soghra Mehrid, Bamdad Riahi-Zanjanie, Karimi, G*,. Protective effects of glucosamine hydrochlorideagainst free radical-induced erythrocytes damage. Damage. Environmental Toxicology and Pharmacology 3 8 ( 2 0 1 4 ) 212–219(IF: 1.862)
  4.  Z Tayarani-Najaran , A Amiri , Karimi, G, SA Emami , J Asili, S H Mousavi. Comparative Studies of Cytotoxic and Apoptotic Properties of Different Extracts and the Essential Oil of Lavandula angustifolia on Malignant and Normal Cells. Nutrition and Cancer, 2014 Apr;66(3):424-34(IF: 2.47)
  5.  Shiezadeh F, Mousavi SH, Sadegh Amiri M, ranshahi M, Tayarani-Najaran Z and Karimi, G* .Cytotoxic and Apoptotic Potential of Rheum turkestanicum Janisch Root Extract on Human Cancer and Normal Cells. Iranian journal of pharmaceutical science . 2013: 12( 4), Autumn 2013, 811-819
  6. Razavi-Azarkhiavi K, Behravan J, Mosaffa F, Sehatbakhsh S, Shirani K, Karimi G. Protective effects of aqueous and ethanol extracts of rosemary on H2O2-induced oxidative DNA damage in human lymphocytes by comet assay. J Complement Integr Med. 2014 Feb 4;11(1):27-33. doi: 10.1515/jcim-2013-0063.
  7. Hamid Reza Sadeghnia, Faezeh Vahdati Hassani, Hamid Sadeghian, Maryam Miandehi, Farzin Hadizadeh and Karimi, G*. Evaluation of in vitro toxicity of peptide 3 (N-acetyl-Leu-Gly-Leu-COOH)-substituted-β- 4 cyclodextrin derivative, a novel drug carrier, in 5 PC-12 cells. Sadeghnia et al. DARU Journal of Pharmaceutical Sciences 2013, 21:75. (IF:1.11)
  8. Ali Reza Hosseininia , Maryam Vahabzadeh , Marziyeh Rashedinia , Bamdad Riahi-Zanjani,

Karimi, G*. A survey of aflatoxins in sesame seeds imported into Khorasan Province, Iran. Mycotoxin Res. 2013, DOI 10.1007/s12550-013-0186-7.

 

  1. Ramin Rezaee, Mahmoud Mahmoudi, Khalil Abnous, Shahrzad Zamani, Taghizadeh Rabe,

Nafiseh Tabasi, Mahmoud Hashemzaei and Karimi, G *.Cytotoxic effects of crocin on MOLT-4 human leukemia cells. J Complement Integr Med. 2013; 10(1): 1–8

  1. Taghiabadi E, M Imenshahidi, Kh Abnous, F Mosafa, M Sankian,B Memar,6 and Karimi G*. Protective Effect of Silymarin against Acrolein-Induced Cardiotoxicity in Mice.  Evidence-Based Complementary and Alternative Medicine. Volume 2012, 14  pages. (IF:2.18)
  2. HosseinBoskabady M , karimi G , Samarghandian S , Farkhondeh T. Tracheal responsiveness to methacholine and ovalbumin; and lung inflammation in guinea pigs exposed to inhaled lead after sensitization. Ecotoxicology and Environmental Safety ,2012, 86 : 233–238(IF:2.294)
  3. Maleki M, Karimi G, Tafaghodi M, Raftari S, Nahidi Y. Comparison of Intralesional Two Percent Zinc Sulfate and Glucantime Injection in Treatment of Acute Cutaneous Leishmaniasis. Indian Journal of Dermatology, 2012, 57;118-122. (IF:0.388)
  4. Akbari B   , Gharanfoli F , Hassanzadeh Khayyat M, Khashyarmanesh Z  ,  Rezaee R , Karimi G*. Determination of heavy metals in different honey brands from Iranian market, Food Additives and Contaminants, 2012 , 5: 1-7. (IF:1.765)
  5. Rezaee R, Hassanzadeh-Khayyat M, Khashyarmanesh Z, Moallemzadeh Z, F Mehri F, Karimi G*. Determination of parathion, aldicarb and thiobencarb in tap water and bottled mineral water in Mashhad , Iran. Drug and Chemical Toxicology, 2012, 35:1-7.(IF:1.082)
  6.  Karimi G*,aghasizadeh M, razavi M, taghiabadi E. Protective effects of aqueous and ethanolic extracts of Nigella sativa L.and portulaca oleracea L. on free radical induced hemolysis of RBCs.DARU,2011,19:295-300. .(IF:0.773)
    1. Mohajeri S, Karimi G, Aghamohammadian J, Rajabnia khansari M. Clozapine recognition via molecularly imprinted polymers;bulk polymerization versus precipitation method. Journal of Applied Polymer Science, 2011, 121:3590-3595. (IF:1.289)
    2. Karimi G*, Vahabzadeh M, Lari P, Rashedinia M, Moshiri M. Silymarin a promising pharmacological agent for treatment of disease. IJBMS, 2011, 14:308-317. (IF:0)
    3. Mohammadi H, Karimi G, Rezayat SM, Dehpour AR, Shafiee H, Nikfar S, Baeeri M, Sabzevari O, Abdollahi M. Benefit of nanocarrier of magnetic magnesium in rat malathion-induced toxicity and cardiac failure using non-invasive monitoring of electrocardiogram and blood pressure. Toxicol Ind Health.2011, 27:417-429(IF:1.423)
    4.  Hosseinzadeha L, Behravanb J, Mosaffab F, Bahramic G, Bahramidand A, Karimi G*. Curcumin potentiates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells through generation of reactive oxygen species. Food and Chemical Toxicology. 2011, 49: 1102-1109(IF:2.999)
    5.  Riahi, B., Rafatpanah, H., Mahmoudi, M., Memar, B., Brook, A., Tabasi, N., Karimi, G.* Evaluation of suppressive effect of paraquat on innate immunity in Balbc mice. J Immunotoxicology, 2011, 8:39-45(IF:1.22)
    6.  Hosseinzadeh L, Behravan J, Mosaffa F, Karimi G*. Effect of curcumin on doxorubicin induced cytotoxicity in H9C2 cardiomyocyte cells. IJBMS, 2011, 14:49-56(IF:0)
    7. Mohajeri A, Karimi G, Rajabnia m.Clozapine imprinted polymers: synthesis, ccharacterization and application for drug assay In human serum. Analytica Chimica Acta, 2010, 683: 143-148. (IF:4.555)
    8. Karimi G*, Hosseinzadeh h, Rassoulzadeh M, Razavi M, Taghiabadi E. Antinociceptive effect of Elaeagnus angustifolia fruits on sciatic nerve ligated mice. IJBMS, 2010, 13: 97-101. (IF:0)
    9. Nazemian F, Karimi G. Moatamedi M, Charkazi S, Shamsara J, Mohamadpoor A. Effects of Silymarin administration on TNF-α Serum concentration in peritoneal dialysis patients. Phytotherapy Res, 2010, 24:1654-1657(IF:2.086)
    10.  Karimi G*, Khoei A, Omidi A, Kalantari M, Babaei J, Taghiabadi E, Razavi M. Protective Effects of Aqueous and Ethanolic Extracts of Portulaca oleraceae against cisplatin induced nephrotoxicity. IJBMS, 2010, 13: 31-35. (IF:0)
    11.  Karimi G*, Moallem A, Hasanzadeh M, Bozorgi M, Nilli-Ahmadabadi A, Nazari F. Exposure assessment for mercury from consumption of marine fish in Iran. Toxicological & Environmental Chemistry . 2010, 92: 1213-1218. (IF:2.809)
    12.  Imenshahidi, M., Karimi, G., Kazemzadeh, E.Effects of atorvastatin on nitrate tolerance in diabetic rats. Iranian Journal of Pharmaceutical Research. 2010, 9: 55-59. (IF:0. 637)
    13. Riahi, B., Rafatpanah, H., Mahmoudi, M., Memar, B., Brook, A., Tabasi, N., Karimi, G*.- Immunotoxicity of paraquat after subacute exposure to mice.Food and Chemical Toxicology. 2010, 48: 1627-1631.(IF:2.999)
    14.  Soltani, F., Mosaffa, F., Iranshahi, M., Karimi, G., Malekaneh, M., Haghighi, F., Behravan, J. Auraptene from Ferula szowitsiana protects human peripheral lymphocytes against oxidative stress. Phytotherapy Research. 2010, 24: 85-89. (IF:2.086)
    15. Hadizadeh F., Rahimi B., Taghiabadi E.  , Razavi M., Karimi G*. Evaluation of anticonvulsant effect of two novels 4-[1-(4-fluorobenzyl)-5-imidazolyl] dihydropyridine derivatives in mice. Research in Pharmaceutical Sciences, May 2013; 8(2): 91-95
    16. -Imenshahidi M 1, Rezaee R 2, MostofI A , Karimi G  *. Evaluation of nitric oxide or opioid receptors involvement in antinociceptive properties of silymarin1. AJP, 2012 , 2:39-45

 

  1. Iranshahi M, Khoshangosht M, Mohammadkhani Z, Karimi G*. Protective effect of aqueous and ethanolic extract of saffron stigma and petal on liver toxicity in duced by carbon tetrachloride in mice. Pharmacologyonline , 2011,1: 203-212
    1. Behravan J, Mosaffa F, Soudmand N, Taghiabadi E, Razavi M,Karimi G*. Protective effects of aqueous and ethanolic extracts of Portulaca oleracea L. aerial parts H2O2-induced DNA damage in lymphocytes by comet assay. J Acupunct Meridian Stud( jams) .2011,4:193-197
    2. Karimi G*, Iranshahi M, Hosseinzadeh F, Riahi B, Sahebkar A. Screening of acetylcholinesterase inhibitory activity of terpenoid and coumarin derivatives from the gens ferula. Pharmacologyonline, 2010, 1: 566-574
    3. Moosavifar N, Mohammad poor A, Jalali M, Karimi G, Saberi H. Evaluation of silymarin effect on granulose cell apoptosis and follicular development inpatients in patients undergoing IVF. EMHJ, 2010, 16 : 460-463
    4. Karimi, G*., Tabrizian, K., Rezaee, R.Evaluation of the Analgesic Effect of Dextromethorphan and its Interaction With Nitric Oxide on Sciatic Nerve Ligated Rats. Journal of Acupuncture and Meridian Studies. 2010, 3: 38-42
    5. Roohbakhsh, A., Karimi, G*.- In vitro evaluation of xanthine oxidase inhibitory activity of aqueous extracts of six medicinal plants. Journal of Medicinal Plants. 2009, 8: 84-91.
    6. -Karimi, G.*, Imenshahidi, M., Jafarizaveh, E., Asgharian Rezaee, M.Vasodilator effect of olive leaf aqueous extract and involvment of cyclooxygenase in the rat aorta. Pharmacologyonline. 2009, 2: 365-371
    7. Karimi, G*.., Hassanzadeh, M., Shahidi, N., Samie, Z.Quantitative determination of methanol in plant water produced in Mashhad by spectrophotometry method. Journal of Medicinal Plants. 2008, 7:56-59
    8. Karimi, G*., Saradeghi Keisari, M. Evaluation of antidepressant effect of ethanolic and aqueous extracts of Silybum marianum L. seed in mice. Journal of Medicinal Plants. 2007, 6: 38-43
    9. Behravan, J., Mosaffa, F., Karimi, G.Iranshahi, M. In vitro protective effects of Satureja hortensis L. essential oil and ethanolic extract on lymphocytes DNA. Journal of Medicinal Plants. 2007, 6: 64-70
    10. -Karimi, G*., Hassanzadeh, M., Mehri, S. Protective effects of silymarin against free radical-induced erythrocyte lysis. Journal of Complementary and Integrative Medicine. 2006, 3: 1553-3840
    11.  Karimi, G*., Taiebi, N., Hosseinzadeh, Shirzad, F.Evaluation of subacute toxicity of aqueous extract of Crocus sativus L. stigma and petal in rats.Journal of Medicinal Plants. 2004, 3: 29-35
    12. Hosseinzadeh, H., Karimi, G., Niapoor, M.- Antidepressant effects of Crocus sativus stigma extracts and its constituents, crocin and safranal, in mice.Journal of Medicinal Plants. 2004, 3: 48-58
    13. Hosseinzadeh, H., Karimi, G., Rakhshanizadeh, M.Anticonvulsant effects of aqueous and ethanolic extracts of Hypericum perforatum L. in mice.Journal of Medicinal Plants. 2004, 3: 23-30
    14. Hosseinzadeh, H., Karimi, G., Ameri, M.Effects of Anethum graveolens L. seed extracts on experimental gastric irritation models in mice. BMC Pharmacology. 2002, 19; 2-21.
    15. Iranshahi, M., Noroozi, S., Behravan, J., Karimi, G., Schneider, B.Persicasulphide C, a new sulphur-containing derivative from Ferula persica. Natural Product Research .2009, 23: 1584-1588(IF:1.009)
    16. Soltani, F., Mosaffa, F., Iranshahi, M., Karimi, G., Malekaneh, M., Haghighi, F., Behravan, J. Evaluation of antigenotoxicity effects of umbelliprenin on human peripheral lymphocytes exposed to oxidative stress.Cell Biology and Toxicology. 2009,25: 291-296. (IF:2.511)
    17. Noroozi, S., Mosaffa, F., Soltani, F., Iranshahi, M., Karimi, G., Malekaneh, M., Haghighi, F., Behravan, J. Antigenotoxic effects of the disulfide compound persicasulfide A (PSA) on rat lymphocytes exposed to oxidative stress. Planta Medica. 2009,75::32-36. (IF:2.04)
    18. Karimi, G*, Hassanzadeh, M., Yazdanpanah, H., Nazari, F., Iranshahi, M., Nili, A.Contamination of patulin in clear apple juice in Mashhad, Iran. Journal of Food Safety. 2008, 28: 413-421. (IF:1.9)
    19. Karimi, G*, Fatehi, Z., Gholamnejad, Z.The role of nitric oxide and protein kinase C in lipopolysaccharide- mediated vascular hyporeactivity. Journal of Pharmacy and Pharmaceutical Sciences. 2006, 9: 119-123. (IF:1. 914)
    20. Mosaffa, F., Behravan, J., Karimi, G., Iranshahi, M.Antigenotoxic effects of Satureja hortensis L. on rat lymphocytes exposed to oxidative stress. Archives of Pharmacal Research. 2006, 29:159-164. (IF:1.592)
    21. Karimi, G*., Ramezani, M., Abdi, A. Protective effects of lycopene and tomato extract against doxorubicin-induced cardiotoxicity. Phytotherapy Research. 2005, 19: 912-914. (IF:2.08)
    22. Karimi, G*., Ramezani, M., Tahoonian, Z. Cisplatin nephrotoxicity and protection by milk thistle extract in rats. Evidence-based Complementary and Alternative Medicine. 2005, 2: 383-386. (IF:4.7)
    23. Hosseinzadeh, H., Karimi, G .Rakhshanizadeh, M.- Anticonvulsant effect of Hypericum perforatum: Role of nitric oxide. Journal of Ethnopharmacology. 2005, 98: 207-208(IF:3.7)
    24. Karimi, G*., Hosseinzadeh, H., Ettehad, N.Evaluation of the gastric antiulcerogenic effects of Portulaca oleracea L. extracts in mice. Phytotherapy Research. 2004, 18: 484-487.(IF: 2.08)
    25. Karimi, G*., Khoshbaten, A., Abdollahi, M., Sharifzadeh, M., Namiranian, K., Dehpour, A.R. Effects of subacute lead acetate administration on nitric oxide and cyclooxygenase pathways in rat isolated aortic ring. Pharmacological Research. 2002, 46: 31-37(IF:2.6)
    26. Abdollahi, M., Jalali, N., Sharifzadeh, M., Karimi, G. Attempted suicide by insulin injection treated with hypertonic glucose solution. Medical Journal of the Islamic Republic of Iran .1998, 12: 85-87

 

                                                                      Presentations

  • Karimi G, Behravan J, Mosaffa F, Hosseinzadeh L, Bahrami G. Curcumin potentiates doxorubicin induced apoptosis in h cardiac muscle cells through generation of reactive oxygen spec.12 th Iranian congress of biochemistry & 4 th International congress of biochemistry and molecular biology.Mashhad ,Iran, 6-9 September, 2011. PP(357)
  • -Hosseinzadeh L, Karimi G .Vation of nuclear factor kappab by doxorubicin leads to ibition of extrinsic pathway of apoptosis in H9c2 cells. 12 th Iranian congress of biochemistry & 4 th International congress of biochemistry and molecular biology.Mashhad ,Iran, 6-9 September, 2011. PP(44)
  • Hosseinzadeh L, Karimi G. Effect of crocin and thymoquinone on doxorubicin- induced cytotoxicity in H9c2 CELLS. Proceeding of 10th Annual Congress of  Asia Pacific Association of medical toxicology, Penang, Malaysia, 11-14 November 2011. PP(101)
  • Mehri F, Rezaee R, Hassanzadeh-Khayyat M, Karimi G . Assay of thiobencarb, aldicarb and parathion in tap water and bottled mineral water in Mashhad, Iran. 11th International congress of Toxicology, Mashhad, Iran, 13-15 September, 2011.(p195)
  • Myelin damage after CO poisoning was recovered by erythropoietin. 12th Iranian Congress of Toxicology, Sari, Iran, 15-17 May 2013.

 

  • The role of microRNA in cardiovascular disease. 12th Iranian Congress of Toxicology, Sari, Iran, 15-17 May 2013.
  • Protective effects of glucosamine hydrochloride against AAPH induced hemolysis. 12th Iranian Congress of Toxicology, Sari, Iran, 15-17 May 2013.
  • Should crocin be regarded as an effective medicine against Human Myeloma cells? 12th Iranian Congress of Toxicology, Sari, Iran, 15-17 May 2013.
  • Preparation and evaluation of histamine imprinted polymer as a selective sorbent in molecularly imprinted solid-phase extraction coupled with high performance liquid chromatography analysis in canned fish. 12th Iranian Congress of Toxicology, Sari, Iran, 15-17 May 2013.
  • Protective effect of vitamin E against acrolein-inducedcardiotoxicity in mice. 12th Iranian Congress of Toxicology, Sari, Iran, 15-17 May 2013.
  • Immunotoxicity of paraquat after subacute exposure to mice. 12th Iranian Congress of Toxicology, Sari, Iran, 15-17 May 2013.

 

 

                                                                    Honors & Awards

 

 

 

 

 

Members                                                  hip Membership

 

 

                                                           Administrative Responsibilities

 

Head of pharmacology and toxicology department,  2000-2002

Manager of pharmacology Lab, 2000 up to now

Manager of Mashhad drug and poison information center, 2000 up to 2012

Deputy food and drug organization in Mashhad University 2005 up to 2012

 

Head of pharmacology and toxicology department,  2014-2016

 

 

 

 

 

Other Skills